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H Jane Dyson
Department of Molecular Biology MB2, The Scripps Research Institute, La Jolla, United States of America

Faculty Member: Structural Biology > Protein Folding [ since 24 July 2001 ]
[ Homepage ] [ Evaluations ]
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http://www.scripps.edu/mb/dyson/

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Evaluations

Hidden alternative structures of proline isomerase essential for catalysis.
Fraser JS, Clarkson MW, …, Kern D, Alber T
Nature 2009 Dec 3 462(7273):669-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fred Dyda / Gira Bhabha and H Jane Dyson / David Cowburn
Evaluated 18 Jan 2010

A minimal sequence code for switching protein structure and function.
Alexander PA, He Y, …, Orban J, Bryan PN
Proc Natl Acad Sci U S A 2009 Dec 15 106(50):21149-54 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Alina Peterson and Adolfo Garcia-Sastre / Gira Bhabha and H Jane Dyson
Evaluated 12 Jan 2010

Molecularly imprinted microgels as enzyme inhibitors.
Cutivet A, Schembri C, Kovensky J, Haupt K
J Am Chem Soc 2009 Oct 21 131(41):14699-702 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bethany Buck-Koehntop and H Jane Dyson / Sivakumar Annadurai and Daniel Canney
Evaluated 19 Oct 2009

The structural role of the zinc ion can be dispensable in prokaryotic zinc-finger domains.
Baglivo I, Russo L, …, Fattorusso R, Pedone PV
Proc Natl Acad Sci U S A 2009 Apr 28 106(17):6933-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bethany Buck-Koehntop and H Jane Dyson
Evaluated 23 Jul 2009

Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, …, Segal DJ, Ghosh I
Bioorg Med Chem Lett 2009 Jul 15 19(14):3748-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bethany Buck-Koehntop and H Jane Dyson
Evaluated 23 Jul 2009

Synergy of NMR, computation, and X-ray crystallography for structural biology.
Szymczyna BR, Taurog RE, …, Johnson JE, Williamson JR
Structure 2009 Apr 15 17(4):499-507 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson / Vicky Higman and Linda Ball
Evaluated 10 Jun 2009

Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering.
An Y, Chen CY, …, Wilson IA, Balch WE
J Mol Biol 2009 Aug 7 391(1):26-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson / Bruno Goud
Evaluated 1 Jun 2009

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex.
Ortega-Roldan JL, Jensen MR, …, Blackledge M, van Nuland NA
Nucleic Acids Res 2009 Apr 9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bethany Buck-Koehntop and H Jane Dyson
Evaluated 22 Apr 2009

Characterization of the intrinsic and TSC2-GAP-regulated GTPase activity of Rheb by real-time NMR.
Marshall CB, Ho J, …, Ikura M, Stambolic V
Sci Signal 2009 2(55):ra3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bethany Buck-Koehntop and H Jane Dyson
Evaluated 12 Mar 2009

Sensing peptide-oligonucleotide interactions by a two-color fluorescence label: application to the HIV-1 nucleocapsid protein.
Shvadchak VV, Klymchenko AS, de Rocquigny H, Mély Y
Nucleic Acids Res 2009 Feb 37(3):e25 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bethany Buck-Koehntop and H Jane Dyson
Evaluated 11 Feb 2009

The nature of the globular- to fibrous-actin transition.
Oda T, Iwasa M, …, Maéda Y, Narita A
Nature 2009 Jan 22 457(7228):441-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Sept / Gira Bhabha and H Jane Dyson / Linda Amos
Evaluated 29 Jan 2009

Conformational flexibility of metazoan fatty acid synthase enables catalysis.
Brignole EJ, Smith S, Asturias FJ
Nat Struct Mol Biol 2009 Jan 18 [abstract on PubMed] [related articles] [full text]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 29 Jan 2009

Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening.
Li M, Hays FA, …, Sali A, Stroud RM
J Mol Biol 2009 Jan 23 385(3):820-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bethany Buck-Koehntop and H Jane Dyson
Evaluated 22 Jan 2009

Multiple receptors involved in human rhinovirus attachment to live cells.
Rankl C, Kienberger F, …, Blaas D, Hinterdorfer P
Proc Natl Acad Sci U S A 2008 Nov 18 105(46):17778-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 5 Jan 2009

Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor.
Mittag T, Orlicky S, …, Tyers M, Forman-Kay JD
Proc Natl Acad Sci U S A 2008 Nov 18 105(46):17772-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gira Bhabha and H Jane Dyson / Wolfgang Jahnke / Vincent Hilser
Evaluated 24 Nov 2008

The Promiscuity of beta-Strand Pairing Allows for Rational Design of beta-Sheet Face Inversion.
Makabe K, Koide S
J Am Chem Soc 2008 Oct 9 [abstract on PubMed] [related articles] [full text]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 23 Oct 2008

NMR structures of two designed proteins with high sequence identity but different fold and function.
He Y, Chen Y, …, Bryan PN, Orban J
Proc Natl Acad Sci U S A 2008 Sep 23 105(38):14412-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gira Bhabha and H Jane Dyson / Mario Pujato and Andras Fiser / Nick Grishin
Evaluated 23 Oct 2008

Dynamics of Ligand Binding from (13)C NMR Relaxation Dispersion at Natural Abundance.
Zintsmaster JS, Wilson BD, Peng JW
J Am Chem Soc 2008 Oct 4 [abstract on PubMed] [related articles] [full text]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 20 Oct 2008

Intrinsically Unstructured Domains of Arf and Hdm2 Form Bimolecular Oligomeric Structures In Vitro and In Vivo.
Sivakolundu SG, Nourse A, …, Lahti J, Kriwacki RW
J Mol Biol 2008 Sep 16 [abstract on PubMed] [related articles] [full text]
Selected by | H Jane Dyson
Evaluated 8 Oct 2008

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug.
Boeckler FM, Joerger AC, …, Veprintsev DB, Fersht AR
Proc Natl Acad Sci U S A 2008 Jul 29 105(30):10360-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 8 Aug 2008

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.
Tang Y, Holbert MA, …, Cole PA, Marmorstein R
Nat Struct Mol Biol 2008 Jul 15(7):738-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson / Stephen Jackson / Xiaodong Cheng
Evaluated 17 Jul 2008

Characterization of the Prefusion and Transition States of Severe Acute Respiratory Syndrome Coronavirus S2-HR2.
McReynolds S, Jiang S, …, Rong L, Caffrey M
Biochemistry 2008 Jul 1 47(26):6802-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 26 Jun 2008

TROSY-based NMR evidence for a novel class of 20S proteasome inhibitors.
Sprangers R, Li X, …, Schimmer AD, Kay LE
Biochemistry 2008 Jul 1 47(26):6727-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson / Wolfgang Jahnke
Evaluated 26 Jun 2008

Quantifying Two-Bond (1)HN-(13)CO and One-Bond (1)H(alpha)-(13)C(alpha) Dipolar Couplings of Invisible Protein States by Spin-State Selective Relaxation Dispersion NMR Spectroscopy.
Hansen DF, Vallurupalli P, Kay LE
J Am Chem Soc 2008 Jun 3 0 [abstract on PubMed] [related articles] [full text]
Selected by | Gira Bhabha and H Jane Dyson
Evaluated 12 Jun 2008

Simultaneous NMR Study of Protein Structure and Dynamics Using Conservative Mutagenesis.
Yao L, Vögeli B, Torchia DA, Bax A
J Phys Chem B 2008 Mar 22 [abstract on PubMed] [related articles] [full text]
Selected by | H Jane Dyson
Evaluated 7 Apr 2008

Structure and dynamics of a molten globular enzyme.
Pervushin K, Vamvaca K, Vögeli B, Hilvert D
Nat Struct Mol Biol 2007 Dec 14(12):1202-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 26 Nov 2007

Probing supramolecular structure from measurement of methyl (1)H-(13)C residual dipolar couplings.
Sprangers R, Kay LE
J Am Chem Soc 2007 Oct 24 129(42):12668-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | H Jane Dyson
Evaluated 12 Oct 2007

Substitutions of prolines examine their role in kinetic trap formation of the caspase recruitment domain (CARD) of RICK.
Chen YR, Clark AC
Protein Sci 2006 Mar 15(3):395-409 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 7 Mar 2006

Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings.
Bouvignies G, Bernadó P, …, Brüschweiler R, Blackledge M
Proc Natl Acad Sci U S A 2005 Sep 27 102(39):13885-90 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 4 Oct 2005

13C NMR relaxation studies of RNA base and ribose nuclei reveal a complex pattern of motions in the RNA binding site for human U1A protein.
Shajani Z, Varani G
J Mol Biol 2005 Jun 17 349(4):699-715 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | H Jane Dyson
Evaluated 20 May 2005

Probing site-specific conformational distributions in protein folding with solid-state NMR.
Havlin RH, Tycko R
Proc Natl Acad Sci U S A 2005 Mar 1 102(9):3284-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 28 Feb 2005

The kinetics of conformational fluctuations in an unfolded protein measured by fluorescence methods.
Chattopadhyay K, Elson EL, Frieden C
Proc Natl Acad Sci U S A 2005 Feb 15 102(7):2385-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 22 Feb 2005

Multiple time scale backbone dynamics of homologous thermophilic and mesophilic ribonuclease HI enzymes.
Butterwick JA, Patrick Loria J, …, Rance M, Palmer AG
J Mol Biol 2004 Jun 11 339(4):855-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | H Jane Dyson / Kathleen Hall
Evaluated 10 Jun 2004

Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".
Friedler A, DeDecker BS, …, Rüdiger S, Fersht AR
J Mol Biol 2004 Feb 6 336(1):187-96 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson / Janet Thornton
Evaluated 9 Feb 2004

Quantitative NMR studies of high molecular weight proteins: application to domain orientation and ligand binding in the 723 residue enzyme malate synthase G.
Tugarinov V, Kay LE
J Mol Biol 2003 Apr 11 327(5):1121-33 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 8 May 2003

Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril.
Jaroniec CP, MacPhee CE, …, Dobson CM, Griffin RG
Proc Natl Acad Sci U S A 2002 Dec 24 99(26):16748-53 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 3 Jan 2003

Co-evolutionary analysis reveals insights into protein-protein interactions.
Goh CS, Cohen FE
J Mol Biol 2002 Nov 15 324(1):177-92 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 20 Dec 2002

Long-range magnetization transfer between uncoupled nuclei by dipole-dipole cross-correlated relaxation: a precise probe of beta-sheet geometry in proteins.
Boisbouvier J, Bax A
J Am Chem Soc 2002 Sep 18 124(37):11038-45 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 24 Sep 2002

Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings.
Koenig BW, Kontaxis G, …, Litman BJ, Bax A
J Mol Biol 2002 Sep 13 322(2):441-61 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 17 Sep 2002

Deuterium spin probes of side-chain dynamics in proteins. 2. Spectral density mapping and identification of nanosecond time-scale side-chain motions.
Skrynnikov NR, Millet O, Kay LE
J Am Chem Soc 2002 Jun 5 124(22):6449-60 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 14 Jun 2002

Deuterium spin probes of side-chain dynamics in proteins. 1. Measurement of five relaxation rates per deuteron in (13)C-labeled and fractionally (2)H-enriched proteins in solution.
Millet O, Muhandiram DR, Skrynnikov NR, Kay LE
J Am Chem Soc 2002 Jun 5 124(22):6439-48 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 13 Jun 2002

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation.
Beglova N, Blacklow SC, Takagi J, Springer TA
Nat Struct Biol 2002 Apr 9(4):282-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kristina Downing / Martin Humphries / Robert Liddington / H Jane Dyson
Evaluated 13 May 2002

TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain.
Frickel EM, Riek R, …, Wuthrich K, Ellgaard L
Proc Natl Acad Sci U S A 2002 Feb 19 99(4):1954-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 22 Feb 2002

Backbone dynamics of the ribonuclease binase active site area using multinuclear ((15)N and (13)CO) NMR relaxation and computational molecular dynamics.
Pang Y, Buck M, Zuiderweg ER
Biochemistry 2002 Feb 26 41(8):2655-66 [abstract on PubMed] [related articles] [order article]
Selected by | H Jane Dyson
Evaluated 22 Feb 2002

NMR structure reveals intramolecular regulation mechanism for pheromone binding and release.
Horst R, Damberger F, …, Leal WS, Wüthrich K
Proc Natl Acad Sci U S A 2001 Dec 4 98(25):14374-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | H Jane Dyson
Evaluated 6 Dec 2001

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
Peretz D, Williamson RA, …, Burton DR, Prusiner SB
Nature 2001 Aug 16 412(6848):739-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | H Jane Dyson
Evaluated 21 Sep 2001

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