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Karen Anderson
Department of Pharmacology, Yale University School of Medicine, New Haven, United States of America

Faculty Member: Chemical Biology > Biocatalysis [ since 4 July 2001 ]
[ Evaluations ]
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Evaluations

Phosphorylation of alpha6-tubulin by protein kinase Calpha activates motility of human breast cells.
Abeyweera TP, Chen X, Rotenberg SA
J Biol Chem 2009 Jun 26 284(26):17648-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karen Anderson
Evaluated 8 Sep 2009

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients.
Gajiwala KS, Wu JC, …, Zhang HM, Demetri GD
Proc Natl Acad Sci U S A 2009 Feb 3 106(5):1542-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karen Anderson
Evaluated 1 Apr 2009

Dynamic binding orientations direct activity of HIV reverse transcriptase.
Abbondanzieri EA, Bokinsky G, …, Le Grice SF, Zhuang X
Nature 2008 May 8 453(7192):184-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karen Anderson
Evaluated 2 Jul 2008


Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3.
Sergina NV, Rausch M, …, Shokat KM, Moasser MM
Nature 2007 Jan 25 445(7126):437-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Abraham / Ruth Roberts / Len Neckers / Karen Anderson
Evaluated 18 Jul 2007


Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, …, Mortensen P, Mann M
Cell 2006 Nov 3 127(3):635-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D Sharrocks / Karen Anderson / Channing Der
Evaluated 24 Nov 2006

Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action.
Jochmans D, Deval J, …, Götte M, Hertogs K
J Virol 2006 Dec 80(24):12283-92 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karen Anderson
Evaluated 20 Oct 2006

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
Zhang X, Gureasko J, …, Cole PA, Kuriyan J
Cell 2006 Jun 16 125(6):1137-49 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Superti-Furga / Stevan Hubbard / Xiayang Qiu / Gourisankar Ghosh / Karen Anderson / Elizabeth Goldsmith / Friedemann Kiefer / Jane Endicott / Frank Sicheri
Evaluated 28 Jun 2006

Functional human mitochondrial DNA polymerase gamma forms a heterotrimer.
Yakubovskaya E, Chen Z, …, Kisker C, Bogenhagen DF
J Biol Chem 2006 Jan 6 281(1):374-82 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karen Anderson
Evaluated 25 Apr 2006

Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.
Tao WA, Wollscheid B, …, Hood L, Aebersold R
Nat Methods 2005 Aug 2(8):591-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Chernoff / Karen Anderson
Evaluated 4 Apr 2006

Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14.
Depetris RS, Hu J, …, Daly RJ, Hubbard SR
Mol Cell 2005 Oct 28 20(2):325-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karen Anderson
Evaluated 3 Nov 2005

Direct characterization of enzyme-substrate complexes by using electrosonic spray ionization mass spectrometry.
Wiseman JM, Takáts Z, …, Davisson VJ, Cooks RG
Angew Chem Int Ed Engl 2005 Jan 28 44(6):913-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karen Anderson
Evaluated 11 Mar 2005

A mechanism-based cross-linker for the identification of kinase-substrate pairs.
Maly DJ, Allen JA, Shokat KM
J Am Chem Soc 2004 Aug 4 126(30):9160-1 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ross Weatherman / Thomas Kodadek / Manfred Schliwa / Wen-hong Li / Karen Anderson
Evaluated 4 Oct 2004

Phylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthase.
O'Neil RH, Lilien RH, …, Stroud RM, Anderson AC
J Biol Chem 2003 Dec 26 278(52):52980-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Edna Kaneshiro / Karen Anderson / Buddy Ullman
Evaluated 23 Mar 2004

Analysis of protein tyrosine phosphorylation by nanoelectrospray ionization high-resolution tandem mass spectrometry and tyrosine-targeted product ion scanning.
Salek M, Alonso A, Pipkorn R, Lehmann WD
Anal Chem 2003 Jun 1 75(11):2724-9 [abstract on PubMed] [related articles] [order article]
Selected by | Karen Anderson
Evaluated 3 Oct 2003

Insights into antifolate resistance from malarial DHFR-TS structures.
Yuvaniyama J, Chitnumsub P, …, Walkinshaw MD, Yuthavong Y
Nat Struct Biol 2003 May 10(5):357-65 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carol Sibley / Vivian Cody / Karen Anderson / Patricia C Weber
Evaluated 13 May 2003

ARTICLE PARTIALLY RETRACTED: Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor.
Zhang L, Yu W, …, Lopez P, Ho DD
Science 2002 Nov 1 298:995-1000 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karen Anderson / Charles Bevins / John Moore / Rino Rappuoli / Mary Carrington / Stefan Kaufmann / Sarah Rowland-Jones
Evaluated 15 Nov 2002

Divergent regulation of dihydrofolate reductase between malaria parasite and human host.
Zhang K, Rathod PK
Science 2002 Apr 19 296(5567):545-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Matthews / Ruma Banerjee / Patricia C Weber / Karen Anderson
Evaluated 7 Jun 2002

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