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Cheng-Ming Chiang
Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, United States of America

Faculty Member: Cell Biology > Control of Gene Expression [ since 19 January 2004 ]
[ Homepage ] [ Evaluations ]
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http://www.utsouthwestern.edu/findfac/professional/0,2356,95126,00.html

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Evaluations

C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
Wethmar K, Bégay V, …, Calkhoven CF, Leutz A
Genes Dev 2010 Jan 1 24(1):15-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 19 Jan 2010

Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells.
Xu J, Watts JA, …, Zaret KS, Smale ST
Genes Dev 2009 Dec 15 23(24):2824-38 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 5 Jan 2010

DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation.
Chen Y, Yamaguchi Y, …, Hisatake K, Handa H
Genes Dev 2009 Dec 1 23(23):2765-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Dinah Singer
Evaluated 10 Dec 2009

SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.
Huang C, Han Y, …, Tang X, Yi J
EMBO J 2009 Aug 13 [abstract on PubMed] [related articles] [full text]
Selected by | Cheng-Ming Chiang
Evaluated 25 Aug 2009

Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint.
Huang W, Ghisletti S, …, Rosenfeld MG, Glass CK
Mol Cell 2009 Jul 10 35(1):48-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 20 Jul 2009

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.
Ghisletti S, Huang W, …, Rosenfeld MG, Glass CK
Genes Dev 2009 Mar 15 23(6):681-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 17 Apr 2009

Histone modifications at human enhancers reflect global cell-type-specific gene expression.
Heintzman ND, Hon GC, …, Kellis M, Ren B
Nature 2009 May 7 459(7243):108-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alon Goren and Brad Bernstein / Cheng-Ming Chiang / Stephen Schwartz / Jason B. Wright and Michael Cole
Evaluated 6 Apr 2009

Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1.
Zhu S, Goeres J, …, Salvesen GS, Matunis MJ
Mol Cell 2009 Mar 13 33(5):570-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 25 Mar 2009

Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling.
Stehmeier P, Muller S
Mol Cell 2009 Feb 13 33(3):400-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 27 Feb 2009

Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA.
Huang B, Yang XD, …, Ozato K, Chen LF
Mol Cell Biol 2009 Mar 29(5):1375-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 18 Feb 2009

Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes.
Wang HK, Duffy AA, Broker TR, Chow LT
Genes Dev 2009 Jan 8 [abstract on PubMed] [related articles] [full text]
Selected by | Cheng-Ming Chiang
Evaluated 19 Jan 2009

The SIRT2 Deacetylase Regulates Autoacetylation of p300.
Black JC, Mosley A, …, Washburn M, Carey M
Mol Cell 2008 Nov 7 32(3):449-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 12 Nov 2008

Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.
Yamagata K, Daitoku H, …, Kasuya Y, Fukamizu A
Mol Cell 2008 Oct 24 32(2):221-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Junjie Chen
Evaluated 30 Oct 2008

Caudal, a key developmental regulator, is a DPE-specific transcriptional factor.
Juven-Gershon T, Hsu JY, Kadonaga JT
Genes Dev 2008 Oct 15 22(20):2823-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 28 Oct 2008

CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response.
Filippi S, Latini P, …, Egly JM, Proietti-De-Santis L
EMBO J 2008 Oct 8 27(19):2545-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 27 Oct 2008

TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription.
Hsu JY, Juven-Gershon T, …, Tjian R, Kadonaga JT
Genes Dev 2008 Sep 1 22(17):2353-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 9 Sep 2008

Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3.
Sen GL, Webster DE, …, Chang HY, Khavari PA
Genes Dev 2008 Jul 15 22(14):1865-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 25 Jul 2008

The bromodomain protein brd4 stimulates G1 gene transcription and promotes progression to S phase.
Mochizuki K, Nishiyama A, …, Yao H, Ozato K
J Biol Chem 2008 Apr 4 283:9040-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 17 Apr 2008

FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.
Heo K, Kim H, …, Yang AS, An W
Mol Cell 2008 Apr 11 30(1):86-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 16 Apr 2008

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription.
LeRoy G, Rickards B, Flint SJ
Mol Cell 2008 Apr 11 30(1):51-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 16 Apr 2008

Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression.
Yang Z, He N, Zhou Q
Mol Cell Biol 2008 Feb 28(3):967-76 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 16 Apr 2008

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity.
Zhao X, Jankovic V, …, Tempst P, Nimer SD
Genes Dev 2008 Mar 1 22(5):640-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 13 Mar 2008

Human Alu RNA is a modular transacting repressor of mRNA transcription during heat shock.
Mariner PD, Walters RD, …, Kugel JF, Goodrich JA
Mol Cell 2008 Feb 29 29(4):499-509 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Sui Huang / Anne-Catherine Dock-Bregeon
Evaluated 6 Mar 2008

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus.
Jing H, Vakoc CR, …, Zheng X, Blobel GA
Mol Cell 2008 Feb 1 29(2):232-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 27 Feb 2008

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo.
Kurash JK, Lei H, …, Li E, Gaudet F
Mol Cell 2008 Feb 15 29(3):392-400 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 20 Feb 2008

Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor.
Reinke H, Saini C, …, Benjamin IJ, Schibler U
Genes Dev 2008 Feb 1 22(3):331-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Andrew D. Sharrocks / Mark Caddick
Evaluated 13 Feb 2008

Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation.
Zhou W, Zhu P, …, Glass CK, Rosenfeld MG
Mol Cell 2008 Jan 18 29(1):69-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 5 Feb 2008

Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Takahashi K, Tanabe K, …, Tomoda K, Yamanaka S
Cell 2007 Nov 30 131(5):861-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Graf / Cheng-Ming Chiang / John Mullins / Maria Blasco / Michael Cole
Evaluated 30 Nov 2007


Induced pluripotent stem cell lines derived from human somatic cells.
Yu J, Vodyanik MA, …, Slukvin II, Thomson JA
Science 2007 Dec 21 318(5858):1917-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 30 Nov 2007

An acetylation switch in p53 mediates holo-TFIID recruitment.
Li AG, Piluso LG, …, Ladurner AG, Liu X
Mol Cell 2007 Nov 9 28(3):408-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tony Weil / Cheng-Ming Chiang / Dinah Singer / Rivka Dikstein
Evaluated 26 Nov 2007

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.
Anindya R, Aygün O, Svejstrup JQ
Mol Cell 2007 Nov 9 28(3):386-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 26 Nov 2007

SIRT1 deacetylates and positively regulates the nuclear receptor LXR.
Li X, Zhang S, …, Krieger M, Guarente L
Mol Cell 2007 Oct 12 28(1):91-106 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 5 Nov 2007

Modulation of p53 function by SET8-mediated methylation at lysine 382.
Shi X, Kachirskaia I, …, Appella E, Gozani O
Mol Cell 2007 Aug 17 27(4):636-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 30 Aug 2007

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.
Bisgrove DA, Mahmoudi T, Henklein P, Verdin E
Proc Natl Acad Sci U S A 2007 Aug 21 104(34):13690-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 23 Aug 2007

SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress.
Scher MB, Vaquero A, Reinberg D
Genes Dev 2007 Apr 15 21(8):920-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 1 May 2007

MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.
Rinaldo C, Prodosmo A, …, Moretti F, Soddu S
Mol Cell 2007 Mar 9 25(5):739-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 2 Apr 2007

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.
Taira N, Nihira K, …, Miki Y, Yoshida K
Mol Cell 2007 Mar 9 25(5):725-38 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 2 Apr 2007

The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms.
Lassot I, Latreille D, …, Benkirane M, Kiernan RE
Mol Cell 2007 Feb 9 25(3):369-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 2 Mar 2007

Structure of the papillomavirus DNA-tethering complex E2:Brd4 and a peptide that ablates HPV chromosomal association.
Abbate EA, Voitenleitner C, Botchan MR
Mol Cell 2006 Dec 28 24(6):877-89 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 10 Jan 2007

ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance.
Parish JL, Bean AM, Park RB, Androphy EJ
Mol Cell 2006 Dec 28 24(6):867-76 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 10 Jan 2007

Repression of p53 activity by Smyd2-mediated methylation.
Huang J, Perez-Burgos L, …, Jenuwein T, Berger SL
Nature 2006 Nov 30 444(7119):629-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 7 Dec 2006

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.
Le Cam L, Linares LK, …, Coux O, Sardet C
Cell 2006 Nov 17 127(4):775-88 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 7 Dec 2006

The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity.
Okorokov AL, Sherman MB, …, Milner J, Orlova EV
EMBO J 2006 Nov 1 25(21):5191-200 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 6 Nov 2006

A mechanism for coordinating chromatin modification and preinitiation complex assembly.
Black JC, Choi JE, Lombardo SR, Carey M
Mol Cell 2006 Sep 15 23(6):809-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 23 Oct 2006

MafG sumoylation is required for active transcriptional repression.
Motohashi H, Katsuoka F, …, Engel JD, Yamamoto M
Mol Cell Biol 2006 Jun 26(12):4652-63 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 31 Aug 2006

Myc influences global chromatin structure.
Knoepfler PS, Zhang XY, …, McMahon SB, Eisenman RN
EMBO J 2006 Jun 21 25(12):2723-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Andreas Trumpp / Cheng-Ming Chiang
Evaluated 18 Aug 2006

Structural basis of DNA recognition by p53 tetramers.
Kitayner M, Rozenberg H, …, Haran TE, Shakked Z
Mol Cell 2006 Jun 23 22(6):741-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 7 Aug 2006

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage.
Wang H, Zhai L, …, Xiong Y, Zhang Y
Mol Cell 2006 May 5 22(3):383-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 18 May 2006

Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications.
Nathan D, Ingvarsdottir K, …, Johnson ES, Berger SL
Genes Dev 2006 Apr 15 20(8):966-76 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 28 Apr 2006

Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair.
Heale JT, Ball AR, …, Earnshaw WC, Yokomori K
Mol Cell 2006 Mar 17 21(6):837-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 21 Apr 2006

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription.
Zhou H, Spicuglia S, …, Korsmeyer SJ, Stunnenberg HG
Mol Cell Biol 2006 Apr 26(7):2728-35 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 12 Apr 2006

Transcription regulation from a TATA and INR-less promoter: spatial segregation of promoter function.
George AA, Sharma M, …, Sahoo NC, Rao KV
EMBO J 2006 Feb 22 25(4):811-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 20 Feb 2006

Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes.
Bossis G, Melchior F
Mol Cell 2006 Feb 3 21(3):349-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Ron Prywes
Evaluated 14 Feb 2006

p8/TTD-A as a repair-specific TFIIH subunit.
Coin F, Proietti De Santis L, …, Stefanini M, Egly JM
Mol Cell 2006 Jan 20 21(2):215-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 9 Feb 2006

Reconstitution of chromatin transcription with purified components reveals a chromatin-specific repressive activity of p300.
Santoso B, Kadonaga JT
Nat Struct Mol Biol 2006 Feb 13(2):131-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Fisher / Cheng-Ming Chiang
Evaluated 1 Feb 2006

The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.
Lee D, Ezhkova E, …, Tansey WP, Workman JL
Cell 2005 Nov 4 123(3):423-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Susan Forsburg / Benoit Coulombe / Rivka Dikstein / Cheng-Ming Chiang / Dinah Singer / Tony Weil / Michael Meisterernst
Evaluated 22 Nov 2005

Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein.
Zhang XY, DeSalle LM, …, Thomas-Tikhonenko A, McMahon SB
Proc Natl Acad Sci U S A 2005 Sep 27 102(39):13968-73 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 16 Nov 2005

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.
Pascual G, Fong AL, …, Rosenfeld MG, Glass CK
Nature 2005 Sep 29 437(7059):759-63 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Curt Sigmund / Andrew D Sharrocks / Michael Gold / Cheng-Ming Chiang
Evaluated 9 Nov 2005

A core promoter element downstream of the TATA box that is recognized by TFIIB.
Deng W, Roberts SG
Genes Dev 2005 Oct 15 19(20):2418-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang / Benoit Coulombe
Evaluated 2 Nov 2005

p53 isoforms can regulate p53 transcriptional activity.
Bourdon JC, Fernandes K, …, Saville MK, Lane DP
Genes Dev 2005 Sep 15 19(18):2122-37 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 5 Oct 2005

In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation.
Perini G, Diolaiti D, Porro A, Della Valle G
Proc Natl Acad Sci U S A 2005 Aug 23 102(34):12117-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 22 Sep 2005

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4.
Yang Z, Yik JH, …, Ozato K, Zhou Q
Mol Cell 2005 Aug 19 19(4):535-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 2 Sep 2005

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
Jang MK, Mochizuki K, …, Brady JN, Ozato K
Mol Cell 2005 Aug 19 19(4):523-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 2 Sep 2005

Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin.
Kravchenko JE, Rogozin IB, Koonin EV, Chumakov PM
Nature 2005 Aug 4 436(7051):735-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler / Carl Thummel / Pamela Geyer / Cheng-Ming Chiang / Tony Weil
Evaluated 23 Aug 2005

A novel human p53 isoform is an essential element of the ATR-intra-S phase checkpoint.
Rohaly G, Chemnitz J, …, Deppert W, Dornreiter I
Cell 2005 Jul 15 122(1):21-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Jane Endicott
Evaluated 27 Jul 2005

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.
Kovacs JJ, Murphy PJ, …, Pratt WB, Yao TP
Mol Cell 2005 May 27 18(5):601-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Len Neckers / Cheng-Ming Chiang
Evaluated 8 Jun 2005

The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing.
Muratani M, Kung C, Shokat KM, Tansey WP
Cell 2005 Mar 25 120(6):887-99 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Reinhard Luehrmann / Ronald Conaway / Cheng-Ming Chiang
Evaluated 27 Apr 2005

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator.
Pavri R, Lewis B, …, Chambon P, Reinberg D
Mol Cell 2005 Apr 1 18(1):83-96 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 21 Apr 2005

A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73.
Asher G, Tsvetkov P, Kahana C, Shaul Y
Genes Dev 2005 Feb 1 19(3):316-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 9 Mar 2005

Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway.
Ju BG, Solum D, …, Glass CK, Rosenfeld MG
Cell 2004 Dec 17 119(6):815-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Means / Cheng-Ming Chiang
Evaluated 17 Jan 2005

Regulation of p53 activity through lysine methylation.
Chuikov S, Kurash JK, …, Barlev NA, Reinberg D
Nature 2004 Nov 18 432(7015):353-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Jenuwein / Cheng-Ming Chiang
Evaluated 7 Jan 2005

Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53.
Dornan D, Eckert M, …, Hupp TR, Ball KL
Mol Cell Biol 2004 Nov 24(22):10083-98 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 26 Nov 2004

A common set of gene regulatory networks links metabolism and growth inhibition.
Cam H, Balciunaite E, …, Kluger Y, Dynlacht BD
Mol Cell 2004 Nov 5 16(3):399-411 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 22 Nov 2004

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes.
Korenjak M, Taylor-Harding B, …, Dyson N, Brehm A
Cell 2004 Oct 15 119(2):181-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 4 Nov 2004

Human PAD4 regulates histone arginine methylation levels via demethylimination.
Wang Y, Wysocka J, …, Allis CD, Coonrod SA
Science 2004 Oct 8 306(5694):279-83 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Thomas Kodadek / Cheng-Ming Chiang / Robert Dutnall
Evaluated 29 Oct 2004

The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2.
Abbate EA, Berger JM, Botchan MR
Genes Dev 2004 Aug 15 18(16):1981-96 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 17 Sep 2004

Cohesin relocation from sites of chromosomal loading to places of convergent transcription.
Lengronne A, Katou Y, …, Shirahige K, Uhlmann F
Nature 2004 Jul 29 430(6999):573-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Orna Cohen-Fix / Susan Forsburg / Stephen Kearsey / Cheng-Ming Chiang
Evaluated 23 Aug 2004

Precise nucleosome positioning and the TATA box dictate requirements for the histone H4 tail and the bromodomain factor Bdf1.
Martinez-Campa C, Politis P, …, Mellor J, Goding CR
Mol Cell 2004 Jul 2 15(1):69-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Jeffrey Hayes / Rivka Dikstein
Evaluated 29 Jul 2004

Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53.
An W, Kim J, Roeder RG
Cell 2004 Jun 11 117(6):735-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 30 Jun 2004

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.
Sato S, Tomomori-Sato C, …, Conaway JW, Conaway RC
Mol Cell 2004 Jun 4 14(5):685-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Cheng-Ming Chiang / Michael Meisterernst
Evaluated 28 Jun 2004

Molecular recognition of the nucleosomal "supergroove".
Edayathumangalam RS, Weyermann P, …, Dervan PB, Luger K
Proc Natl Acad Sci U S A 2004 May 4 101(18):6864-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Cheng-Ming Chiang
Evaluated 27 May 2004

Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes.
You J, Croyle JL, …, Ozato K, Howley PM
Cell 2004 Apr 30 117(3):349-60 [abstract on PubMed] [related articles] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 7 May 2004

From silencing to gene expression: real-time analysis in single cells.
Janicki SM, Tsukamoto T, …, Singer RH, Spector DL
Cell 2004 Mar 5 116(5):683-98 [abstract on PubMed] [related articles] [order article]
Selected by | Genevieve Almouzni / Cheng-Ming Chiang / Jonathan Sweedler
Evaluated 1 Apr 2004

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Mujtaba S, He Y, …, Ronai Z, Zhou MM
Mol Cell 2004 Jan 30 13(2):251-63 [abstract on PubMed] [related articles] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 17 Mar 2004

Selective recognition of acetylated histones by bromodomain proteins visualized in living cells.
Kanno T, Kanno Y, …, Lenardo MJ, Ozato K
Mol Cell 2004 Jan 16 13(1):33-43 [abstract on PubMed] [related articles] [order article]
Selected by | Cheng-Ming Chiang
Evaluated 5 Feb 2004

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