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Ian Dunham
European Bioinformatics Institute (EBI), Hinxton, United Kingdom

Faculty Member: Genomics & Genetics > Genomics [ since 6 July 2001 ]
[ Evaluations ]
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Evaluations

Nucleosome organization in the Drosophila genome.
Mavrich TN, Jiang C, …, Albert I, Pugh BF
Nature 2008 May 15 453(7193):358-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tony Weil / Ian Dunham
Evaluated 5 Dec 2008

Combinatorial patterns of histone acetylations and methylations in the human genome.
Wang Z, Zang C, …, Zhang MQ, Zhao K
Nat Genet 2008 Jul 40(7):897-903 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Isaac Kohane / Ian Dunham
Evaluated 18 Jul 2008

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions.
Guelen L, Pagie L, …, de Laat W, van Steensel B
Nature 2008 Jun 12 453(7197):948-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rob White / Brad Bernstein / Ian Dunham / Mark Caddick / Susan Mango
Evaluated 13 Jun 2008

Genome analysis of the platypus reveals unique signatures of evolution.
Warren WC, Hillier LW, …, Mardis ER, Wilson RK
Nature 2008 May 8 453(7192):175-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham
Evaluated 14 May 2008

Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21.
Lyle R, Prandini P, …, Reymond A, Antonarakis SE
Genome Res 2007 Nov 17(11):1690-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham
Evaluated 14 Apr 2008

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
Mikkelsen TS, Ku M, …, Lander ES, Bernstein BE
Nature 2007 Aug 2 448(7153):553-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hans de Jong / Ian Dunham
Evaluated 7 Mar 2008

Closing gaps in the human genome with fosmid resources generated from multiple individuals.
Bovee D, Zhou Y, …, Eichler EE, Kaul R
Nat Genet 2008 Jan 40(1):96-101 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham / Hans de Jong
Evaluated 28 Jan 2008

Polycomb complexes repress developmental regulators in murine embryonic stem cells.
Boyer LA, Plath K, …, Young RA, Jaenisch R
Nature 2006 May 18 441(7091):349-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham
Evaluated 12 Jun 2006

A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
Bernstein BE, Mikkelsen TS, …, Schreiber SL, Lander ES
Cell 2006 Apr 21 125(2):315-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham
Evaluated 9 Jun 2006

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans.
Aitman TJ, Dong R, …, Pusey CD, Cook HT
Nature 2006 Feb 16 439(7078):851-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Manuel Serrano / Gerardo Gamba / Ian Dunham / Sue Malcolm
Evaluated 14 Mar 2006


Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1.
Gabellini D, D'Antona G, …, Green MR, Tupler R
Nature 2006 Feb 23 439(7079):973-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Elizabeth McNally / Pamela Geyer / Peter Scambler / Ian Dunham
Evaluated 13 Mar 2006

Single-nucleosome mapping of histone modifications in S. cerevisiae.
Liu CL, Kaplan T, …, Friedman N, Rando OJ
PLoS Biol 2005 Oct 3(10):e328 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham
Evaluated 17 Nov 2005

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease.
Loots GG, Kneissel M, …, Plajzer-Frick I, Rubin EM
Genome Res 2005 Jul 15(7):928-35 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham / Veronica van Heyningen
Evaluated 23 Aug 2005


Comprehensive identification and characterization of diallelic insertion-deletion polymorphisms in 330 human candidate genes.
Bhangale TR, Rieder MJ, Livingston RJ, Nickerson DA
Hum Mol Genet 2005 Jan 1 14(1):59-69 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham
Evaluated 1 Feb 2005

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division.
Kittler R, Putz G, …, Pisabarro MT, Buchholz F
Nature 2004 Dec 23 432(7020):1036-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham
Evaluated 28 Jan 2005

Recombination rate and reproductive success in humans.
Kong A, Barnard J, …, Gulcher JR, Stefansson K
Nat Genet 2004 Nov 36(11):1203-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham / Carmen Sapienza
Evaluated 1 Nov 2004

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote.
Schübeler D, MacAlpine DM, …, Bell SP, Groudine M
Genes Dev 2004 Jun 1 18(11):1263-71 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Yasushi Okazaki / Ian Dunham / Thomas Jenuwein
Evaluated 14 Oct 2004

Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
Yen L, Svendsen J, …, D'Amato RJ, Mulligan RC
Nature 2004 Sep 23 431(7007):471-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham / Fritz Eckstein
Evaluated 1 Oct 2004

Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes.
Han JS, Szak ST, Boeke JD
Nature 2004 May 20 429(6989):268-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lucio Comai / Ian Dunham / Ulf Pettersson
Evaluated 11 Jun 2004

Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs.
Cawley S, Bekiranov S, …, Struhl K, Gingeras TR
Cell 2004 Feb 20 116(4):499-509 [abstract on PubMed] [related articles] [order article]
Selected by | Ian Dunham / Carlos F Barbas / Andrew D Sharrocks
Evaluated 8 Mar 2004

A tiling resolution DNA microarray with complete coverage of the human genome.
Ishkanian AS, Malloff CA, …, MacAulay C, Lam WL
Nat Genet 2004 Mar 36(3):299-303 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham / Jeff Woessner
Evaluated 5 Mar 2004

Distribution of NF-kappaB-binding sites across human chromosome 22.
Martone R, Euskirchen G, …, Weissman S, Snyder M
Proc Natl Acad Sci U S A 2003 Oct 14 100(21):12247-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham
Evaluated 13 Nov 2003

Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication.
Azuara V, Brown KE, …, Merkenschlager M, Fisher AG
Nat Cell Biol 2003 Jul 5(7):668-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Pierre Ferrier / Rudolf Grosschedl / Ian Dunham
Evaluated 13 Oct 2003

Sequencing and comparison of yeast species to identify genes and regulatory elements.
Kellis M, Patterson N, …, Birren B, Lander ES
Nature 2003 May 15 423(6937):241-54 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D Sharrocks / Ian Dunham / Motoaki Seki
Evaluated 16 Jun 2003

Initial sequencing and comparative analysis of the mouse genome.
Waterston RH, Lindblad-Toh K, …, Lander ES, Mouse Genome Sequencing Consortium
Nature 2002 Dec 5 420(6915):520-62 [abstract on PubMed] [related articles] [order article]
Selected by | Ian Dunham
Evaluated 19 May 2003

Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing.
Schübeler D, Scalzo D, …, Delrow J, Groudine M
Nat Genet 2002 Nov 32(3):438-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wendy Bickmore / Ian Dunham
Evaluated 12 Dec 2002

Allelic variation in human gene expression.
Yan H, Yuan W, …, Vogelstein B, Kinzler KW
Science 2002 Aug 16 297(5584):1143 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham / Michael O'Donovan
Evaluated 5 Sep 2002

Human-specific duplication and mosaic transcripts: the recent paralogous structure of chromosome 22.
Bailey JA, Yavor AM, …, Rocchi M, Eichler EE
Am J Hum Genet 2002 Jan 70(1):83-100 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham
Evaluated 23 May 2002

Identification of novel genes coding for small expressed RNAs.
Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T
Science 2001 Oct 26 294(5543):853-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Sarnow / Oliver Weichenrieder / David Tollervey / Ian Dunham
Evaluated 16 May 2002

Direct measurement of the male recombination fraction in the human beta-globin hot spot.
Schneider JA, Peto TE, …, Boyce AJ, Clegg JB
Hum Mol Genet 2002 Feb 1 11(3):207-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham
Evaluated 26 Mar 2002

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.
Elbashir SM, Harborth J, …, Weber K, Tuschl T
Nature 2001 May 24 411(6836):494-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean Schwarzbauer / Andrew Belmont / Brenda Bass / Mariann Bienz / Ian Dunham
Evaluated 25 Mar 2002

Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21.
Patil N, Berno AJ, …, Fodor SP, Cox DR
Science 2001 Nov 23 294(5547):1719-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham / Karin Schmitt / Magnus Nordborg
Evaluated 7 Dec 2001

Population genetic structure of variable drug response.
Wilson JF, Weale ME, …, Bradman N, Goldstein DB
Nat Genet 2001 Nov 29(3):265-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham / Greg Gibson
Evaluated 3 Dec 2001

Haplotype tagging for the identification of common disease genes.
Johnson GC, Esposito L, …, Clayton DG, Todd JA
Nat Genet 2001 Oct 29(2):233-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jurg Ott / Ian Dunham
Evaluated 24 Oct 2001

Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex.
Jeffreys AJ, Kauppi L, Neumann R
Nat Genet 2001 Oct 29(2):217-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ian Dunham / Anna Di Rienzo / Magnus Nordborg / Andrew Wilkie / Mary Carrington / David Altshuler
Evaluated 24 Oct 2001

Evolutionarily conserved sequences on human chromosome 21.
Frazer KA, Sheehan JB, …, Cox DR, Patil N
Genome Res 2001 Oct 11(10):1651-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ian Dunham / Karin Schmitt
Evaluated 23 Oct 2001

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