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Bryan Williams
Monash Institute of Medical Research, Clayton, Australia

Faculty Member: Microbiology > Virology [ since 2 February 2006 ]
[ Evaluations ]
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Evaluations

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.
Yanai H, Ban T, …, Kodama T, Taniguchi T
Nature 2009 Nov 5 462(7269):99-103 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Gantier and Bryan Williams
Evaluated 15 Jan 2010

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses.
Kortylewski M, Swiderski P, …, Jove R, Yu H
Nat Biotechnol 2009 Oct 27(10):925-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Gantier and Bryan Williams
Evaluated 11 Nov 2009

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.
Calvo SE, Pagliarini DJ, Mootha VK
Proc Natl Acad Sci U S A 2009 May 5 106(18):7507-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Devin Scannell and Michael Eisen / Michael Gantier and Bryan Williams
Evaluated 4 Sep 2009

Activation of MDA5 requires higher order RNA structures generated during virus infection.
Pichlmair A, Schulz O, …, Schiavo G, Reis E Sousa C
J Virol 2009 Aug 5 [abstract on PubMed] [related articles] [full text]
Selected by | Bryan Williams
Evaluated 13 Aug 2009

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.
Matsushita K, Takeuchi O, …, Nakamura H, Akira S
Nature 2009 Apr 30 458(7242):1185-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Jean Pieters
Evaluated 6 Apr 2009


STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Ishikawa H, Barber GN
Nature 2008 Oct 2 455(7213):674-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Michael Gale / Grant McFadden / Adolfo Garcia-Sastre
Evaluated 8 Sep 2008

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA.
Saito T, Owen DM, …, Marcotrigiano J, Gale M
Nature 2008 Jul 24 454(7203):523-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Grant McFadden
Evaluated 17 Jun 2008

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman ME, Yamada K, …, Taylor EW, Ambati J
Nature 2008 Apr 3 452(7187):591-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Murali Ramanathan / Richard Vile / Mark Boothby / Miles Wilkinson
Evaluated 1 Apr 2008


TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines.
Ishii KJ, Kawagoe T, …, Coban C, Akira S
Nature 2008 Feb 7 451(7179):725-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Jean Pieters
Evaluated 12 Feb 2008

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis.
Swann JB, Vesely MD, …, Schreiber RD, Smyth MJ
Proc Natl Acad Sci U S A 2008 Jan 15 105(2):652-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Alberto Mantovani
Evaluated 16 Jan 2008

DUBA: a deubiquitinase that regulates type I interferon production.
Kayagaki N, Phung Q, …, Arnott D, Dixit VM
Science 2007 Dec 7 318(5856):1628-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Grant McFadden / Bryan Williams
Evaluated 19 Dec 2007


Interferon modulation of cellular microRNAs as an antiviral mechanism.
Pedersen IM, Cheng G, …, Chisari FV, David M
Nature 2007 Oct 18 449(7164):919-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Richard Locksley / Robert Krug
Evaluated 22 Oct 2007

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
Roberts ZJ, Goutagny N, …, Ching LM, Vogel SN
J Exp Med 2007 Jul 9 204(7):1559-69 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams
Evaluated 23 Aug 2007

Small self-RNA generated by RNase L amplifies antiviral innate immunity.
Malathi K, Dong B, Gale M, Silverman RH
Nature 2007 Aug 16 448(7155):816-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Caetano Reis e Sousa / Bryan Williams / David Leib / Philippe Pierre / Grant McFadden
Evaluated 21 Aug 2007

Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression.
Otsuka M, Jing Q, …, Beutler B, Han J
Immunity 2007 Jul 27(1):123-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams
Evaluated 15 Aug 2007

Immunostimulatory RNA is a potent inducer of antigen-specific cytotoxic and humoral immune response in vivo.
Hamm S, Heit A, …, Wagner H, Bauer S
Int Immunol 2007 Mar 19(3):297-304 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams
Evaluated 22 Mar 2007

An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors.
Dong B, Kim S, …, Chow SA, Silverman RH
Proc Natl Acad Sci U S A 2007 Jan 30 104(5):1655-60 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joe Heitman / Bryan Williams
Evaluated 22 Mar 2007

IkappaB kinase epsilon interacts with p52 and promotes transactivation via p65.
Wietek C, Cleaver CS, …, Ray KP, O'Neill LA
J Biol Chem 2006 Nov 17 281(46):34973-81 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bryan Williams
Evaluated 16 Oct 2006

Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.
Lang KS, Georgiev P, …, Hengartner H, Zinkernagel RM
J Clin Invest 2006 Sep 116(9):2456-63 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bryan Williams
Evaluated 20 Sep 2006

Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
McGettrick AF, Brint EK, …, Fitzgerald KA, O'Neill LA
Proc Natl Acad Sci U S A 2006 Jun 13 103(24):9196-201 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bryan Williams
Evaluated 19 Jun 2006

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.
Saitoh T, Tun-Kyi A, …, Lu KP, Yamaoka S
Nat Immunol 2006 Jun 7(6):598-605 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Steve Ward / Michael Gale
Evaluated 25 May 2006

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
Kanneganti TD, Ozören N, …, Akira S, Núñez G
Nature 2006 Mar 9 440(7081):233-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams
Evaluated 8 May 2006

Role of p38 MAPK and RNA-dependent protein kinase (PKR) in hepatitis C virus core-dependent nuclear delocalization of cyclin B1.
Spaziani A, Alisi A, Sanna D, Balsano C
J Biol Chem 2006 Apr 21 281(16):10983-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bryan Williams
Evaluated 10 Mar 2006

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