Murray Stewart sponsors free access to F1000 for University of the South Pacific, Suva, Fiji. Supporting F1000's initiative to make itself available to scientists in all countries, including free access to developing countries (more details).

http://www2.mrc-lmb.cam.ac.uk/SS/Stewart_M/group/

Six classes of nuclear localization signals specific to different binding grooves of importin alpha. Kosugi S, Hasebe M, …, Tomita M, Yanagawa H J Biol Chem 2008 Nov 10 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 10 Dec 2008 Improved success of sparse matrix protein crystallization screening with heterogeneous nucleating agents. Thakur AS, Robin G, …, Martin JL, Kobe B PLoS ONE 2007 2(10):e1091 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 25 Jul 2008 Conformational heterogeneity of karyopherin beta2 is segmental. Cansizoglu AE, Chook YM Structure 2007 Nov 15(11):1431-41 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 13 Dec 2007 Molecular basis for bre5 cofactor recognition by the ubp3 deubiquitylating enzyme. Li K, Ossareh-Nazari B, …, Dargemont C, Marmorstein R J Mol Biol 2007 Sep 7 372(1):194-204 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 24 Jul 2007 Efficiency, selectivity, and robustness of nucleocytoplasmic transport. Zilman A, Di Talia S, …, Rout MP, Magnasco MO PLoS Comput Biol 2007 Jul 3(7):e125 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 23 Jul 2007 The use of Co2+ for crystallization and structure determination, using a conventional monochromatic X-ray source, of flax rust avirulence protein. Guncar G, Wang CI, …, Dodds PN, Kobe B Acta Crystallograph Sect F Struct Biol Cryst Commun 2007 Mar 1 63(Pt 3):209-13 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 7 Mar 2007 Association of nuclear pore FG-repeat domains to NTF2 import and export complexes. Isgro TA, Schulten K J Mol Biol 2007 Feb 9 366(1):330-45 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 19 Jan 2007 Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo. Timney BL, Tetenbaum-Novatt J, …, Chait BT, Rout MP J Cell Biol 2006 Nov 20 175(4):579-93 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 8 Dec 2006 Rules for nuclear localization sequence recognition by karyopherin beta 2. Lee BJ, Cansizoglu AE, …, Zhang Z, Chook YM Cell 2006 Aug 11 126(3):543-58 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 24 Aug 2006 Nuclear localization signal receptor affinity correlates with in vivo localization in Saccharomyces cerevisiae. Hodel AE, Harreman MT, …, Berland KM, Corbett AH J Biol Chem 2006 Aug 18 281(33):23545-56 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 14 Jul 2006 Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport. Lim RY, Huang NP, …, Fahrenkrog B, Aebi U Proc Natl Acad Sci U S A 2006 Jun 20 103(25):9512-7 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / Yosef Gruenbaum Evaluated 19 Jun 2006 NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Ribbeck K, Groen AC, …, Hoenger A, Mattaj IW Mol Biol Cell 2006 Jun 17(6):2646-60 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 30 May 2006 Importin-beta mediates Cdc7 nuclear import by binding to the kinase insert II domain, which can be antagonized by importin-alpha. Kim BJ, Lee H J Biol Chem 2006 Apr 28 281(17):12041-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 30 May 2006 Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Kaláb P, Pralle A, …, Heald R, Weis K Nature 2006 Mar 30 440(7084):697-701 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 24 May 2006 Excluded volume effect on confined polymer translocation through a short nanochannel. Xie Y, Yang H, …, Wang X, Chen J J Chem Phys 2006 May 7 124(17):174906 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 24 May 2006 The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis. von Bergen M, Barghorn S, …, Aebi U, Mandelkow E Biochemistry 2006 May 23 45(20):6446-57 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 24 May 2006 An automatable screen for the rapid identification of proteins amenable to refolding. Cowieson NP, Wensley B, …, Kobe B, Martin JL Proteomics 2006 Mar 6(6):1750-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 24 May 2006 Protein kinases associated with the yeast phosphoproteome. Brinkworth RI, Munn AL, Kobe B BMC Bioinformatics 2006 7:47 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 7 Feb 2006 Arp2/3 complex-deficient mouse fibroblasts are viable and have normal leading-edge actin structure and function. Di Nardo A, Cicchetti G, …, Stossel TP, Kwiatkowski DJ Proc Natl Acad Sci U S A 2005 Nov 8 102(45):16263-8 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / Alfred Wittinghofer Evaluated 7 Nov 2005 Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Hantschel O, Wiesner S, …, Sattler M, Superti-Furga G Mol Cell 2005 Aug 19 19(4):461-73 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Ilaria Rebay / Murray Stewart Evaluated 25 Aug 2005 Crm1 is a mitotic effector of Ran-GTP in somatic cells. Arnaoutov A, Azuma Y, …, McNally J, Dasso M Nat Cell Biol 2005 Jun 7(6):626-32 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 26 May 2005 The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding. Cook A, Fernandez E, …, Schlenstedt G, Conti E Mol Cell 2005 Apr 29 18(3):355-67 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 9 May 2005 A systems analysis of importin-{alpha}-{beta} mediated nuclear protein import. Riddick G, Macara IG J Cell Biol 2005 Mar 28 168(7):1027-38 [abstract on PubMed] [related articles] [FREE full text] Selected by | Tom Misteli / Murray Stewart Evaluated 26 Apr 2005 Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori. Terradot L, Bayliss R, …, Baron C, Waksman G Proc Natl Acad Sci U S A 2005 Mar 22 102(12):4596-601 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 30 Mar 2005 Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling. Itoh K, Brott BK, …, Ratcliffe MJ, Sokol SY J Biol 2005 4(1):3 [abstract on PubMed] [related articles] [FREE full text] Selected by | David Kimelman / Herbert Steinbeisser / Ken Irvine / Murray Stewart / Avri Ben-Ze'ev / Inke Nathke Evaluated 30 Mar 2005 Nuclear transport of single molecules: dwell times at the nuclear pore complex. Kubitscheck U, Grünwald D, …, Siebrasse JP, Peters R J Cell Biol 2005 Jan 17 168(2):233-43 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 31 Jan 2005 Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex. Berke IC, Boehmer T, Blobel G, Schwartz TU J Cell Biol 2004 Nov 22 167(4):591-7 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / Susan Wente / Elena Conti Evaluated 3 Dec 2004 The FG-repeat asymmetry of the nuclear pore complex is dispensable for bulk nucleocytoplasmic transport in vivo. Zeitler B, Weis K J Cell Biol 2004 Nov 22 167(4):583-90 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 30 Nov 2004 Regulated fast nucleocytoplasmic shuttling observed by reversible protein highlighting. Ando R, Mizuno H, Miyawaki A Science 2004 Nov 19 306(5700):1370-3 [abstract on PubMed] [related articles] [FREE full text] Selected by | Philippe I. Bastiaens / Murray Stewart / Natalie Ahn / Julian Schroeder Evaluated 30 Nov 2004 A mechanism for inhibiting the SUMO pathway. Boggio R, Colombo R, …, Draetta GF, Chiocca S Mol Cell 2004 Nov 19 16(4):549-61 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart / Robert Krug / David Wotton Evaluated 25 Nov 2004 The assembly of MreB, a prokaryotic homolog of actin. Esue O, Cordero M, Wirtz D, Tseng Y J Biol Chem 2005 Jan 28 280(4):2628-35 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 25 Nov 2004 The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Jínek M, Rehwinkel J, …, Hanover JA, Conti E Nat Struct Mol Biol 2004 Oct 11(10):1001-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 20 Sep 2004 Imaging of single-molecule translocation through nuclear pore complexes. Yang W, Gelles J, Musser SM Proc Natl Acad Sci U S A 2004 Aug 31 101(35):12887-92 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 19 Aug 2004 Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export. Zhao R, Shen J, …, MacMorris M, Blumenthal T Structure 2004 Aug 12(8):1373-81 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 19 Aug 2004 Soft Listeria: actin-based propulsion of liquid drops. Boukellal H, Campás O, …, Prost J, Sykes C Phys Rev E Stat Nonlin Soft Matter Phys 2004 Jun 69(6 Pt 1):061906 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart Evaluated 18 Aug 2004 The role of substrate curvature in actin-based pushing forces. Schwartz IM, Ehrenberg M, Bindschadler M, McGrath JL Curr Biol 2004 Jun 22 14(12):1094-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart / Ed Manser / Jonathan Scholey Evaluated 30 Jun 2004 Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Casolari JM, Brown CR, …, Hieronymus H, Silver PA Cell 2004 May 14 117(4):427-39 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart / Susan Wente Evaluated 8 Jun 2004 An ATP-dependent activity that releases RanGDP from NTF2. Yamada M, Mattaj IW, Yoneda Y J Biol Chem 2004 Aug 27 279(35):36228-34 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 4 Jun 2004 Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells. Lorenz M, Yamaguchi H, …, Singer RH, Condeelis J Curr Biol 2004 Apr 20 14(8):697-703 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart / Christopher Turner Evaluated 23 Apr 2004 Minimal nuclear pore complexes define FG repeat domains essential for transport. Strawn LA, Shen T, …, Goldfarb DS, Wente SR Nat Cell Biol 2004 Mar 6(3):197-206 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Ilan Davis / Murray Stewart / Karsten Weis Evaluated 1 Apr 2004 Conserved nuclear export sequences in Schizosaccharomyces pombe Mex67 and human TAP function in mRNA export by direct nuclear pore interactions. Thakurta AG, Gopal G, …, Saha T, Dhar R J Biol Chem 2004 Apr 23 279(17):17434-42 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 27 Feb 2004 Yeast nuclear pore complexes have a cytoplasmic ring and internal filaments. Kiseleva E, Allen TD, …, Wente SR, Goldberg MW J Struct Biol 2004 Mar 145(3):272-88 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 27 Feb 2004 Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery. Rodríguez-Navarro S, Fischer T, …, Reed R, Hurt E Cell 2004 Jan 9 116(1):75-86 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart / Tony Weil / Peter B. Becker / Francesc Posas Evaluated 23 Jan 2004 The structure of importin-beta bound to SREBP-2: nuclear import of a transcription factor. Lee SJ, Sekimoto T, …, Tsukihara T, Yoneda Y Science 2003 Nov 28 302(5650):1571-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / Elena Conti Evaluated 12 Dec 2003 Virtual gating and nuclear transport: the hole picture. Rout MP, Aitchison JD, Magnasco MO, Chait BT Trends Cell Biol 2003 Dec 13(12):622-8 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart Evaluated 2 Dec 2003 Conformational variability of nucleo-cytoplasmic transport factors. Fukuhara N, Fernandez E, …, Conti E, Svergun D J Biol Chem 2004 Jan 16 279(3):2176-81 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 27 Oct 2003 Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo. Galy V, Mattaj IW, Askjaer P Mol Biol Cell 2003 Dec 14(12):5104-15 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 27 Oct 2003 Optical microwell assay of membrane transport kinetics. Kiskin NI, Siebrasse JP, Peters R Biophys J 2003 Oct 85(4):2311-22 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 27 Oct 2003 The COPI complex functions in nuclear envelope breakdown and is recruited by the nucleoporin Nup153. Liu J, Prunuske AJ, Fager AM, Ullman KS Dev Cell 2003 Sep 5(3):487-98 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart / Mary Dasso Evaluated 29 Sep 2003 Nuclear import of hepatitis B virus capsids and release of the viral genome. Rabe B, Vlachou A, …, Helenius A, Kann M Proc Natl Acad Sci U S A 2003 Aug 19 100(17):9849-54 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 28 Aug 2003 Importin beta contains a COOH-terminal nucleoporin binding region important for nuclear transport. Bednenko J, Cingolani G, Gerace L J Cell Biol 2003 Aug 4 162(3):391-401 [abstract on PubMed] [related articles] [FREE full text] Selected by | Karsten Weis / Murray Stewart Evaluated 27 Aug 2003 Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15. Fribourg S, Conti E EMBO Rep 2003 Jul 4(7):699-703 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 7 Jul 2003 A novel nuclear export signal in Smad1 is essential for its signaling activity. Xiao Z, Brownawell AM, Macara IG, Lodish HF J Biol Chem 2003 Sep 5 278(36):34245-52 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 1 Jul 2003 Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex. Hase ME, Cordes VC Mol Biol Cell 2003 May 14(5):1923-40 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 25 Jun 2003 Importin beta-depending nuclear import pathways: role of the adapter proteins in the docking and releasing steps. Rollenhagen C, Mühlhäusser P, Kutay U, Panté N Mol Biol Cell 2003 May 14(5):2104-15 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 25 Jun 2003 The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. Longman D, Johnstone IL, Cáceres JF RNA 2003 Jul 9(7):881-91 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 24 Jun 2003 A novel mode of RBD-protein recognition in the Y14-Mago complex. Fribourg S, Gatfield D, Izaurralde E, Conti E Nat Struct Biol 2003 Jun 10(6):433-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart / Oliver Weichenrieder Evaluated 23 Jun 2003 In vitro analysis of nuclear mRNA export using molecular beacons for target detection. Kehlenbach RH Nucleic Acids Res 2003 Jun 1 31(11):e64 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 23 Jun 2003 The Ran GTPase cycle is required for yeast nuclear pore complex assembly. Ryan KJ, McCaffery JM, Wente SR J Cell Biol 2003 Mar 31 160(7):1041-53 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 23 Jun 2003 Genome-wide analysis of nuclear mRNA export pathways in Drosophila. Herold A, Teixeira L, Izaurralde E EMBO J 2003 May 15 22(10):2472-83 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 20 May 2003 The strategy for coupling the RanGTP gradient to nuclear protein export. Becskei A, Mattaj IW Proc Natl Acad Sci U S A 2003 Feb 18 100(4):1717-22 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 7 Apr 2003 Comparison of three commercial sparse-matrix crystallization screens. Wooh JW, Kidd RD, Martin JL, Kobe B Acta Crystallogr D Biol Crystallogr 2003 Apr 59(Pt 4):769-72 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart Evaluated 7 Apr 2003 Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. Görlich D, Seewald MJ, Ribbeck K EMBO J 2003 Mar 3 22(5):1088-100 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 5 Mar 2003 The nuclear pore complex mystery and anomalous diffusion in reversible gels. Bickel T, Bruinsma R Biophys J 2002 Dec 83(6):3079-87 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 21 Feb 2003 Structural basis and prediction of substrate specificity in protein serine/threonine kinases. Brinkworth RI, Breinl RA, Kobe B Proc Natl Acad Sci U S A 2003 Jan 7 100(1):74-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Rolf Apweiler / Murray Stewart Evaluated 17 Jan 2003 Binding dynamics of structural nucleoporins govern nuclear pore complex permeability and may mediate channel gating. Shulga N, Goldfarb DS Mol Cell Biol 2003 Jan 23(2):534-42 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 17 Jan 2003 NLSdb: database of nuclear localization signals. Nair R, Carter P, Rost B Nucleic Acids Res 2003 Jan 1 31(1):397-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 17 Jan 2003 Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta. Cingolani G, Bednenko J, Gillespie MT, Gerace L Mol Cell 2002 Dec 10(6):1345-53 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart / Caroline Hill / Elena Conti Evaluated 17 Jan 2003 Crp79p, like Mex67p, is an auxiliary mRNA export factor in Schizosaccharomyces pombe. Thakurta AG, Whalen WA, …, Hanover JA, Dhar R Mol Biol Cell 2002 Aug 13(8):2571-84 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 28 Aug 2002 Pure F-actin networks are distorted and branched by steps in the critical-point drying method. Resch GP, Goldie KN, Hoenger A, Small JV J Struct Biol 2002 Mar 137(3):305-12 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart Evaluated 28 Aug 2002 Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Lindsay ME, Plafker K, …, Clurman BE, Macara IG Cell 2002 Aug 9 110(3):349-60 [abstract on PubMed] [related articles] [order article] Selected by | Murray Stewart Evaluated 28 Aug 2002 The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. Ribbeck K, Görlich D EMBO J 2002 Jun 3 21(11):2664-71 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart Evaluated 14 Jun 2002 The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form. Nilsson J, Weis K, Kjems J J Mol Biol 2002 Apr 26 318(2):583-93 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart Evaluated 14 Jun 2002 TREX is a conserved complex coupling transcription with messenger RNA export. Strässer K, Masuda S, …, Reed R, Hurt E Nature 2002 May 16 417(6886):304-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Murray Stewart / Daniel Reines Evaluated 10 May 2002 Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Kalab P, Weis K, Heald R Science 2002 Mar 29 295(5564):2452-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Murray Stewart / David Morgan Evaluated 1 May 2002

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