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Karl-Peter Giese
Centre for the Cellular Basis of Behaviour, Institute of Psychiatry, King's College London, London, United Kingdom

Faculty Member: Neuroscience > Cognitive Neuroscience [ since 9 July 2001 ]
[ Homepage ] [ Evaluations ]
Home page

http://www.iop.kcl.ac.uk/departments/?locator=622&context=867

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Evaluations

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc.
Greer PL, Hanayama R, …, Steen J, Greenberg ME
Cell 2010 Mar 5 140(5):704-716 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 12 Mar 2010

Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines.
Bingol B, Wang CF, …, Peng J, Sheng M
Cell 2010 Feb 19 140(4):567-78 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Johannes Hell
Evaluated 5 Mar 2010

Amyloid beta from axons and dendrites reduces local spine number and plasticity.
Wei W, Nguyen LN, …, Sisodia S, Malinow R
Nat Neurosci 2010 Feb 13(2):190-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 8 Feb 2010


[CONFERENCE POSTER] Mechanisms of enhancement and reconsolidation of reactivated fear memory in passive avoidance task.
Fukushima H, Zhang Y, Kida S
Neuroscience 2009 Conference 2009 Oct 17–21:782.2 [order article]
Selected by | Karl-Peter Giese
Evaluated 25 Nov 2009

Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory.
Kitamura T, Saitoh Y, …, Sugiyama H, Inokuchi K
Cell 2009 Nov 13 139(4):814-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Amar Sahay and Rene Hen / Dori Derdikman and Edvard I Moser
Evaluated 18 Nov 2009

Sleep deprivation impairs cAMP signalling in the hippocampus.
Vecsey CG, Baillie GS, …, Houslay MD, Abel T
Nature 2009 Oct 22 461(7267):1122-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Fine / Karl-Peter Giese / Silvana Curci
Evaluated 3 Nov 2009

The phosphatase SHP2 regulates the spacing effect for long-term memory induction.
Pagani MR, Oishi K, Gelb BD, Zhong Y
Cell 2009 Oct 2 139(1):186-98 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Kristin Anderson and Anthony Means
Evaluated 14 Oct 2009

Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.
Roberts AC, Díez-García J, …, Philpot BD, Pérez-Otaño I
Neuron 2009 Aug 13 63(3):342-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 18 Aug 2009

Presenilins are essential for regulating neurotransmitter release.
Zhang C, Wu B, …, Südhof TC, Shen J
Nature 2009 Jul 30 460(7255):632-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Stephen Fitzjohn and Graham Collingridge / Robert Burgoyne
Evaluated 11 Aug 2009


Activation of CaMKII in single dendritic spines during long-term potentiation.
Lee SJ, Escobedo-Lozoya Y, Szatmari EM, Yasuda R
Nature 2009 Mar 19 458(7236):299-304 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Johannes Hell / Nikolai Otmakhov and John Lisman
Evaluated 25 Mar 2009

Functional MRI evidence for LTP-induced neural network reorganization.
Canals S, Beyerlein M, Merkle H, Logothetis NK
Curr Biol 2009 Mar 10 19(5):398-403 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 24 Mar 2009

Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene.
Roth TL, Lubin FD, Funk AJ, Sweatt JD
Biol Psychiatry 2009 Jan 14 [abstract on PubMed] [related articles] [full text]
Selected by | Keiko Mizuno and Karl-Peter Giese
Evaluated 10 Mar 2009


The precision of remote context memories does not require the hippocampus.
Wang SH, Teixeira CM, Wheeler AL, Frankland PW
Nat Neurosci 2009 Mar 12(3):253-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Benedetta Leuner and Elizabeth Gould / Norman White
Evaluated 20 Feb 2009

Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment.
Arai JA, Li S, Hartley DM, Feig LA
J Neurosci 2009 Feb 4 29(5):1496-502 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Mareshia Donald and John Lisman / Mark Westhusin
Evaluated 13 Feb 2009

Contribution of KCNQ2 and KCNQ3 to the medium and slow afterhyperpolarization currents.
Tzingounis AV, Nicoll RA
Proc Natl Acad Sci U S A 2008 Dec 16 105(50):19974-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 4 Feb 2009

Inducible and selective erasure of memories in the mouse brain via chemical-genetic manipulation.
Cao X, Wang H, …, Wang LP, Tsien JZ
Neuron 2008 Oct 23 60(2):353-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Dori Derdikman and Edvard I. Moser
Evaluated 7 Nov 2008


Memory reconsolidation mediates the strengthening of memories by additional learning.
Lee JL
Nat Neurosci 2008 Nov 11(11):1264-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 30 Oct 2008

Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging.
Fukushima H, Maeda R, …, Zhuo M, Kida S
J Neurosci 2008 Oct 1 28(40):9910-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 15 Oct 2008

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
Shankar GM, Li S, …, Sabatini BL, Selkoe DJ
Nat Med 2008 Aug 14(8):837-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jane Sullivan / Keiko Mizuno and Karl-Peter Giese
Evaluated 24 Sep 2008


Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory.
Bolduc FV, Bell K, …, Broadie KS, Tully T
Nat Neurosci 2008 Sep 7 [abstract on PubMed] [related articles] [full text]
Selected by | Karl-Peter Giese
Evaluated 23 Sep 2008

Persistent sodium current is a nonsynaptic substrate for long-term associative memory.
Nikitin ES, Vavoulis DV, …, Benjamin PR, Kemenes G
Curr Biol 2008 Aug 26 18(16):1221-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Randolf Menzel / Karl-Peter Giese
Evaluated 23 Sep 2008

A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.
Dreses-Werringloer U, Lambert JC, …, Campagne F, Marambaud P
Cell 2008 Jun 27 133(7):1149-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Keiko Mizuno and Karl-Peter Giese
Evaluated 11 Jul 2008


White matter in learning, cognition and psychiatric disorders.
Fields RD
Trends Neurosci 2008 Jul 31(7):361-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 3 Jul 2008

Activation of LVGCCs and CB1 receptors required for destabilization of reactivated contextual fear memories.
Suzuki A, Mukawa T, …, Frankland PW, Kida S
Learn Mem 2008 15(6):426-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 3 Jul 2008

Critical role of TRPC6 channels in the formation of excitatory synapses.
Zhou J, Du W, …, Ding Y, Wang Y
Nat Neurosci 2008 Jul 11(7):741-743 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Keiko Mizuno and Karl-Peter Giese
Evaluated 27 Jun 2008

Reversal of learning deficits in a Tsc2(+/-) mouse model of tuberous sclerosis.
Ehninger D, Han S, …, Ramesh V, Silva AJ
Nat Med 2008 Jun 22 [abstract on PubMed] [related articles] [full text]
Selected by | Karl-Peter Giese
Evaluated 27 Jun 2008


Inducible cAMP early repressor acts as a negative regulator for kindling epileptogenesis and long-term fear memory.
Kojima N, Borlikova G, …, Niki H, Endo S
J Neurosci 2008 Jun 18 28(25):6459-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Keiko Mizuno and Karl-Peter Giese
Evaluated 26 Jun 2008

Synaptic protein degradation underlies destabilization of retrieved fear memory.
Lee SH, Choi JH, …, Kim H, Kaang BK
Science 2008 Feb 29 319(5867):1253-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Angus Nairn / Michael Ehlers / Karl-Peter Giese / Jean-Antoine Girault
Evaluated 10 Mar 2008

Spine-type-specific recruitment of newly synthesized AMPA receptors with learning.
Matsuo N, Reijmers L, Mayford M
Science 2008 Feb 22 319(5866):1104-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David P. Wolfer / Karl-Peter Giese / Marina Picciotto / Thomas Biederer / Michael Ehlers / Elizabeth Gould / Edvard I. Moser
Evaluated 29 Feb 2008

Qualitatively different hippocampal subfield engagement emerges with mastery of a spatial memory task by rats.
Poirier GL, Amin E, Aggleton JP
J Neurosci 2008 Jan 30 28(5):1034-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 20 Feb 2008

Activity-Dependent Synaptogenesis: Regulation by a CaM-Kinase Kinase/CaM-Kinase I/betaPIX Signaling Complex.
Saneyoshi T, Wayman G, …, Natsume T, Soderling TR
Neuron 2008 Jan 10 57(1):94-107 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 18 Jan 2008

Ongoing in vivo experience triggers synaptic metaplasticity in the neocortex.
Clem RL, Celikel T, Barth AL
Science 2008 Jan 4 319(5859):101-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yadin Dudai / Johannes Hell / Karl-Peter Giese
Evaluated 18 Jan 2008

Astroglial nuclear factor-kappaB regulates learning and memory and synaptic plasticity in female mice.
Bracchi-Ricard V, Brambilla R, …, Green EJ, Bethea JR
J Neurochem 2008 Feb 104(3):611-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 29 Oct 2007

Emotion enhances learning via norepinephrine regulation of AMPA-receptor trafficking.
Hu H, Real E, …, Huganir RL, Malinow R
Cell 2007 Oct 5 131(1):160-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Johannes Hell / Karl-Peter Giese / Marina Picciotto
Evaluated 29 Oct 2007

Localization of a stable neural correlate of associative memory.
Reijmers LG, Perkins BL, Matsuo N, Mayford M
Science 2007 Aug 31 317(5842):1230-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Edvard I Moser / Matteo Carandini
Evaluated 21 Sep 2007

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.
Hawasli AH, Benavides DR, …, Cooper DC, Bibb JA
Nat Neurosci 2007 Jul 10(7):880-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 23 Jul 2007

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.
Ring S, Weyer SW, …, Wolfer DP, Müller UC
J Neurosci 2007 Jul 18 27(29):7817-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 23 Jul 2007

Recovery of learning and memory is associated with chromatin remodelling.
Fischer A, Sananbenesi F, …, Dobbin M, Tsai LH
Nature 2007 May 10 447(7141):178-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Edvard I Moser
Evaluated 14 May 2007


Neuronal competition and selection during memory formation.
Han JH, Kushner SA, …, Silva AJ, Josselyn SA
Science 2007 Apr 20 316(5823):457-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Michael Kiebler
Evaluated 1 May 2007

Covalent modification of DNA regulates memory formation.
Miller CA, Sweatt JD
Neuron 2007 Mar 15 53(6):857-69 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Ted Abel / Michael Kiebler / Jerry Buccafusco
Evaluated 17 Apr 2007

Schemas and memory consolidation.
Tse D, Langston RF, …, Witter MP, Morris RG
Science 2007 Apr 6 316(5821):76-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Howard Eichenbaum / Karl-Peter Giese / David P Wolfer
Evaluated 17 Apr 2007

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus.
Niewoehner B, Single FN, …, Sprengel R, Bannerman DM
Eur J Neurosci 2007 Feb 25(3):837-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 27 Feb 2007

Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation.
van Woerden GM, Harris KD, …, Elgersma Y, Weeber EJ
Nat Neurosci 2007 Mar 10(3):280-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Michael Ehlers
Evaluated 9 Feb 2007

Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior.
Chen ZY, Jing D, …, Hempstead BL, Lee FS
Science 2006 Oct 6 314(5796):140-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Detlef Weigel / Rene Hen
Evaluated 19 Oct 2006

Storage of spatial information by the maintenance mechanism of LTP.
Pastalkova E, Serrano P, …, Fenton AA, Sacktor TC
Science 2006 Aug 25 313(5790):1141-4 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Edvard I Moser / John Lisman / Yadin Dudai
Evaluated 4 Sep 2006

Learning induces long-term potentiation in the hippocampus.
Whitlock JR, Heynen AJ, Shuler MG, Bear MF
Science 2006 Aug 25 313(5790):1093-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Edvard I Moser / David P Wolfer / Marcos Milla
Evaluated 4 Sep 2006

Retraction of synapses and dendritic spines induced by off-target effects of RNA interference.
Alvarez VA, Ridenour DA, Sabatini BL
J Neurosci 2006 Jul 26 26(30):7820-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gina Turrigiano / Michael Kiebler / Karl-Peter Giese / Hilmar Bading
Evaluated 8 Aug 2006

Involvement of the anterior cingulate cortex in the expression of remote spatial memory.
Teixeira CM, Pomedli SR, …, Kee N, Frankland PW
J Neurosci 2006 Jul 19 26(29):7555-64 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 2 Aug 2006

NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.
Nakazawa T, Komai S, …, Yamamoto T, Manabe T
EMBO J 2006 Jun 21 25(12):2867-77 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 1 Jun 2006

The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.
Schulte U, Thumfart JO, …, Knaus HG, Fakler B
Neuron 2006 Mar 2 49(5):697-706 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Susumu Tomita
Evaluated 6 Mar 2006

Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.
Li S, Tian X, Hartley DM, Feig LA
J Neurosci 2006 Feb 8 26(6):1721-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Leonard Maler
Evaluated 14 Feb 2006

A brain-specific microRNA regulates dendritic spine development.
Schratt GM, Tuebing F, …, Kiebler M, Greenberg ME
Nature 2006 Jan 19 439(7074):283-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Harukazu Nakamura / Allan Tobin / Fritz Eckstein / Alain Prochiantz
Evaluated 23 Jan 2006

Neuronal activity regulates diffusion across the neck of dendritic spines.
Bloodgood BL, Sabatini BL
Science 2005 Nov 4 310(5749):866-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 22 Nov 2005

Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway.
Kushner SA, Elgersma Y, …, Pozzo-Miller L, Silva AJ
J Neurosci 2005 Oct 19 25(42):9721-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 31 Oct 2005

Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms.
Tronel S, Milekic MH, Alberini CM
PLoS Biol 2005 Sep 3(9):e293 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Randolf Menzel
Evaluated 12 Sep 2005

Tau suppression in a neurodegenerative mouse model improves memory function.
Santacruz K, Lewis J, …, Hutton M, Ashe KH
Science 2005 Jul 15 309(5733):476-81 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / M Flint Beal
Evaluated 22 Jul 2005

PI3 kinase signaling is required for retrieval and extinction of contextual memory.
Chen X, Garelick MG, …, Athos J, Storm DR
Nat Neurosci 2005 Jul 8(7):925-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 28 Jun 2005

Reduced sleep in Drosophila Shaker mutants.
Cirelli C, Bushey D, …, Ganetzky B, Tononi G
Nature 2005 Apr 28 434(7037):1087-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carl Thummel / Karl-Peter Giese
Evaluated 17 May 2005

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.
Lazarov O, Robinson J, …, Mirnics K, Sisodia SS
Cell 2005 Mar 11 120(5):701-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Claudia Bagni / Mark Fortini
Evaluated 18 Mar 2005

Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons.
Xu J, Kang N, …, Nedergaard M, Kang J
J Neurosci 2005 Feb 16 25(7):1750-60 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 25 Feb 2005

A role for adult neurogenesis in spatial long-term memory.
Snyder JS, Hong NS, McDonald RJ, Wojtowicz JM
Neuroscience 2005 130(4):843-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 4 Feb 2005

Nuclear calcium/calmodulin regulates memory consolidation.
Limbäck-Stokin K, Korzus E, Nagaoka-Yasuda R, Mayford M
J Neurosci 2004 Dec 1 24(48):10858-67 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 7 Dec 2004

The role of cAMP response element-binding protein in Drosophila long-term memory.
Perazzona B, Isabel G, Preat T, Davis RL
J Neurosci 2004 Oct 6 24(40):8823-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 22 Nov 2004

Role for a cortical input to hippocampal area CA1 in the consolidation of a long-term memory.
Remondes M, Schuman EM
Nature 2004 Oct 7 431(7009):699-703 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Howard Eichenbaum / Randolf Menzel / Karl-Peter Giese / David P Wolfer
Evaluated 11 Oct 2004

VEGF links hippocampal activity with neurogenesis, learning and memory.
Cao L, Jiao X, …, Young D, During MJ
Nat Genet 2004 Aug 36(8):827-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wolfgang Wurst / Karl-Peter Giese / Alain Prochiantz
Evaluated 7 Sep 2004

Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.
Middei S, Geracitano R, …, Mercuri N, Ammassari-Teule M
Learn Mem 2004 Jul-Aug 11(4):447-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 16 Aug 2004

Drosophila long-term memory formation involves regulation of cathepsin activity.
Comas D, Petit F, Preat T
Nature 2004 Jul 22 430(6998):460-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 28 Jul 2004

The involvement of the anterior cingulate cortex in remote contextual fear memory.
Frankland PW, Bontempi B, …, Kaczmarek L, Silva AJ
Science 2004 May 7 304(5672):881-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Edvard I Moser / Howard Eichenbaum
Evaluated 20 May 2004

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.
Cui Z, Wang H, …, Zhang S, Tsien JZ
Neuron 2004 Mar 4 41(5):781-93 [abstract on PubMed] [related articles] [order article]
Selected by | Wendy Suzuki / Jonathan Flint / David P Wolfer / Karl-Peter Giese
Evaluated 14 Apr 2004

Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.
Saura CA, Choi SY, …, Kirkwood A, Shen J
Neuron 2004 Apr 8 42(1):23-36 [abstract on PubMed] [related articles] [order article]
Selected by | Peter Sonderegger / Karl-Peter Giese / Mark Fortini
Evaluated 14 Apr 2004

A role for prefrontal cortex in memory storage for trace fear conditioning.
Runyan JD, Moore AN, Dash PK
J Neurosci 2004 Feb 11 24(6):1288-95 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 19 Feb 2004

Spatiotemporal rescue of memory dysfunction in Drosophila.
McGuire SE, Le PT, …, Matsumoto K, Davis RL
Science 2003 Dec 5 302(5651):1765-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 16 Dec 2003

A requirement for the immediate early gene zif268 in reconsolidation of recognition memory after retrieval.
Bozon B, Davis S, Laroche S
Neuron 2003 Nov 13 40(4):695-701 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese
Evaluated 3 Dec 2003

Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity.
Deller T, Korte M, …, Frotscher M, Mundel P
Proc Natl Acad Sci U S A 2003 Sep 2 100(18):10494-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 5 Sep 2003

A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4.
Bourtchouladze R, Lidge R, …, Scott R, Tully T
Proc Natl Acad Sci U S A 2003 Sep 2 100(18):10518-22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese / Ted Abel
Evaluated 2 Sep 2003

Small-conductance, Ca2+-activated K+ channel SK3 generates age-related memory and LTP deficits.
Blank T, Nijholt I, …, Radulovic J, Spiess J
Nat Neurosci 2003 Sep 6(9):911-2 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 14 Aug 2003

Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression.
Chung HJ, Steinberg JP, Huganir RL, Linden DJ
Science 2003 Jun 13 300(5626):1751-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 8 Jul 2003

Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty.
Li S, Cullen WK, Anwyl R, Rowan MJ
Nat Neurosci 2003 May 6(5):526-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Yadin Dudai
Evaluated 21 May 2003

Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory.
Lee HK, Takamiya K, …, Gallagher M, Huganir RL
Cell 2003 Mar 7 112(5):631-43 [abstract on PubMed] [related articles] [order article]
Selected by | Robert Malenka / Angus Nairn / Karl-Peter Giese
Evaluated 23 Apr 2003

The staufen/pumilio pathway is involved in Drosophila long-term memory.
Dubnau J, Chiang AS, …, Broger C, Tully T
Curr Biol 2003 Feb 18 13(4):286-96 [abstract on PubMed] [related articles] [order article]
Selected by | Ted Abel / Karl-Peter Giese / Ralph Greenspan
Evaluated 11 Mar 2003

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
Egan MF, Kojima M, …, Lu B, Weinberger DR
Cell 2003 Jan 24 112(2):257-69 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Robert Sapolsky / Rene Hen
Evaluated 11 Mar 2003

Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear.
Shumyatsky GP, Tsvetkov E, …, Kandel ER, Bolshakov VY
Cell 2002 Dec 13 111(6):905-18 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Joseph LeDoux
Evaluated 27 Jan 2003

A developmental switch in the signaling cascades for LTP induction.
Yasuda H, Barth AL, Stellwagen D, Malenka RC
Nat Neurosci 2003 Jan 6(1):15-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 20 Dec 2002

Cellular and systems reconsolidation in the hippocampus.
Debiec J, LeDoux JE, Nader K
Neuron 2002 Oct 24 36(3):527-38 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Wendy Suzuki
Evaluated 12 Nov 2002

Hippocampal CRE-mediated gene expression is required for contextual memory formation.
Athos J, Impey S, …, Chen X, Storm DR
Nat Neurosci 2002 Nov 5(11):1119-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 24 Oct 2002

Protein phosphatase 1 is a molecular constraint on learning and memory.
Genoux D, Haditsch U, …, Storm D, Mansuy IM
Nature 2002 Aug 29 418(6901):970-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Alcino Silva / Angus Nairn
Evaluated 6 Sep 2002

Spatial memory dissociations in mice lacking GluR1.
Reisel D, Bannerman DM, …, Seeburg PH, Rawlins JN
Nat Neurosci 2002 Sep 5(9):868-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Howard Eichenbaum
Evaluated 5 Sep 2002

Requirement for hippocampal CA3 NMDA receptors in associative memory recall.
Nakazawa K, Quirk MC, …, Wilson MA, Tonegawa S
Science 2002 Jul 12 297(5579):211-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Michael E. Hasselmo / Karl-Peter Giese / Alcino Silva
Evaluated 25 Jul 2002

Transgenic calmodulin-dependent protein kinase II activation: dose-dependent effects on synaptic plasticity, learning, and memory.
Bejar R, Yasuda R, …, Hood K, Mayford M
J Neurosci 2002 Jul 1 22(13):5719-26 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 23 Jul 2002

Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory.
Mazzucchelli C, Vantaggiato C, …, Pouysségur J, Brambilla R
Neuron 2002 May 30 34(5):807-20 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese
Evaluated 1 Jul 2002

Cyclin-dependent kinase 5 is required for associative learning.
Fischer A, Sananbenesi F, …, Spiess J, Radulovic J
J Neurosci 2002 May 1 22(9):3700-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 5 Jun 2002

Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.
Pittenger C, Huang YY, …, Vronskaya S, Kandel ER
Neuron 2002 Apr 25 34(3):447-62 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Alcino Silva
Evaluated 16 May 2002

CREB required for the stability of new and reactivated fear memories.
Kida S, Josselyn SA, …, Masushige S, Silva AJ
Nat Neurosci 2002 Apr 5(4):348-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wendy Suzuki / Karl-Peter Giese
Evaluated 3 Apr 2002

Somatic action potentials are sufficient for late-phase LTP-related cell signaling.
Dudek SM, Fields RD
Proc Natl Acad Sci U S A 2002 Mar 19 99(6):3962-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 22 Mar 2002

Functional neurogenesis in the adult hippocampus.
van Praag H, Schinder AF, …, Palmer TD, Gage FH
Nature 2002 Feb 28 415(6875):1030-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Eric Nestler
Evaluated 6 Mar 2002

NMDA receptor antagonists sustain LTP and spatial memory: active processes mediate LTP decay.
Villarreal DM, Do V, Haddad E, Derrick BE
Nat Neurosci 2002 Jan 5(1):48-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas S. Collett / Karl-Peter Giese / Randolf Menzel
Evaluated 24 Jan 2002

LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1.
Grosshans DR, Clayton DA, Coultrap SJ, Browning MD
Nat Neurosci 2002 Jan 5(1):27-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese / Gary Aston-Jones
Evaluated 21 Jan 2002

Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory.
Zeng H, Chattarji S, …, Bear MF, Tonegawa S
Cell 2001 Nov 30 107(5):617-29 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese
Evaluated 18 Dec 2001

Inducible, pharmacogenetic approaches to the study of learning and memory.
Ohno M, Frankland PW, …, Costa RM, Silva AJ
Nat Neurosci 2001 Dec 4(12):1238-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Karl-Peter Giese
Evaluated 28 Nov 2001

Regulation of NMDA receptors by cyclin-dependent kinase-5.
Li BS, Sun MK, …, Brady RO, Pant HC
Proc Natl Acad Sci U S A 2001 Oct 23 98(22):12742-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Karl-Peter Giese
Evaluated 2 Nov 2001

Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase.
Patterson SL, Pittenger C, …, Drake C, Kandel ER
Neuron 2001 Oct 11 32(1):123-40 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Ruediger Klein / Randolf Menzel
Evaluated 25 Oct 2001

APP processing and synaptic plasticity in presenilin-1 conditional knockout mice.
Yu H, Saura CA, …, Kirkwood A, Shen J
Neuron 2001 Sep 13 31(5):713-26 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese
Evaluated 25 Oct 2001

A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala.
Lin CH, Yeh SH, …, Chang WC, Gean PW
Neuron 2001 Sep 13 31(5):841-51 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Alcino Silva
Evaluated 19 Oct 2001

An important role of neural activity-dependent CaMKIV signaling in the consolidation of long-term memory.
Kang H, Sun LD, …, Wilson MA, Tonegawa S
Cell 2001 Sep 21 106(6):771-83 [abstract on PubMed] [related articles] [order article]
Selected by | Karl-Peter Giese / Alcino Silva
Evaluated 19 Oct 2001

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