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 | I King Jordan
School of Biology, Georgia Institute of Technology, Atlanta, United States of America | | | Faculty Member: Genomics & Genetics > Bioinformatics [ since 9 December 2008 ] |
| | [ Biography ] [ Homepage ] [ Evaluations ] | Biography
I am an Associate Professor in the School of Biology at the Georgia Institute of Technology. Before coming to Georgia Tech, I received my PhD in Genetics from the University of Georgia and then worked as a Postdoctoral Fellow and Staff Scientist at the National Center for Biotechnology Information. I lead a computational biology laboratory at Georgia Tech -- the Evolutionary Systems Biology Group http://esbg.gatech.edu -- that includes undergraduate, Masters and PhD students majoring in Biology, Bioinformatics and Computer Science. Members of our laboratory investigate genomic evolution, dynamics and systems through the computational analysis of large-scale molecular data sets. The comparative emphasis of our research necessitates the analysis of data from many different species. Much of our work on genome dynamics is done on eukaryotes with an emphasis on the human genome, while our efforts in computational genomics are focused primarily on microbial genomes. We are currently working on three specific areas of research: 1) Transposable elements (TEs) -- the influence of TEs on the structure, function and evolution of eukaryotic genomes. Understanding the relationship between TEs, chromatin structure and gene expression. 2) Regulation -- the tempo and mode of evolutionary changes in patterns of gene regulation and expression as well as the evolutionary origins of regulatory RNAs. Defining changes in gene expression that distinguish normal from cancerous tissues. 3) Computational Genomics -- the development and application of computational tools for analysis of microbial genome sequences. Creation of web-enabled programs for the molecular epidemiological analysis of microbial pathogens. | Home page
http://esbg.gatech.edu/ |
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