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Bernd Nilius
Department of Physiology, KU Leuven, Leuven, Belgium
Faculty Member: Physiology > Integrative Physiology [ since 9 March 2005 ]
[
Evaluations
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Evaluations
Cytochrome P450-Derived Epoxyeicosatrienoic Acids and Pulmonary Hypertension: Central Role of Transient Receptor Potential (TRP) C6 Channels.
Loot AE, Fleming I
J Cardiovasc Pharmacol
2010 Jun 24 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 5 Jul 2010
Molecular basis of infrared detection by snakes.
Gracheva EO, Ingolia NT, …, Weissman JS, Julius D
Nature
2010 Apr 15
464
(7291):1006-11 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Roger Hardie / Felix Viana / Andy Groves / Paul Garrity
Dissenters
| Bernd Nilius
Author Response
|
Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sanchez EE, Perez JC, Weissman JS, Julius D
Evaluated 11 Jun 2010
Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathies.
Zimon M, Baets J, …, Jordanova A, Jonghe PD
Brain
2010 May 11 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 18 May 2010
TRPC1 Is Essential for In Vivo Angiogenesis in Zebrafish.
Yu PC, Gu SY, Bu JW, Du JL
Circ Res
2010 Feb 25 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 10 Mar 2010
TRPV2 has a pivotal role in macrophage particle binding and phagocytosis.
Link TM, Park U, …, Soloski MJ, Caterina MJ
Nat Immunol
2010 Mar
11
(3):232-9 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius / Helen Goodridge and David Underhill / Aaron Neumann and Ken Jacobson / Andrew J Castiglioni and Jaime García-Añoveros
Evaluated 8 Feb 2010
Nociceptive signals induce trafficking of TRPA1 to the plasma membrane.
Schmidt M, Dubin AE, …, Earley TJ, Patapoutian A
Neuron
2009 Nov 25
64
(4):498-509 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius / Paul Garrity
Evaluated 11 Jan 2010
Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride.
Yeo M, Berglund K, Augustine G, Liedtke W
J Neurosci
2009 Nov 18
29
(46):14652-62 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius / Sven Jordt
Evaluated 24 Nov 2009
Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.
Atoyan R, Shander D, Botchkareva NV
J Invest Dermatol
2009 Sep
129
(9):2312-5 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 13 Oct 2009
Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I.
Kruse M, Schulze-Bahr E, …, Brink P, Pongs O
J Clin Invest
2009 Sep
119
(9):2737-44 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius / Jean-Sébastien Rougier and Hugues Abriel
Evaluated 9 Sep 2009
Deletion of TRPC4 and TRPC6 in Mice Impairs Smooth Muscle Contraction and Intestinal Motility In Vivo.
Tsvilovskyy VV, Zholos AV, …, Freichel M, Flockerzi V
Gastroenterology
2009 Jun 21 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 20 Jul 2009
Intracellular Ca2+ signaling and store-operated Ca2+ entry are required in Drosophila neurons for flight.
Venkiteswaran G, Hasan G
Proc Natl Acad Sci U S A
2009 Jun 10 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 18 Jun 2009
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.
Kiyonaka S, Kato K, …, Hamachi I, Mori Y
Proc Natl Acad Sci U S A
2009 Mar 31
106
(13):5400-5 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 12 May 2009
Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca2+-Activated K+ Channels.
Earley S, Gonzales AL, Crnich R
Circ Res
2009 Mar 19 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 2 Apr 2009
Impact of the Gly573Ser substitution in TRPV3 on the development of allergic and pruritic dermatitis in mice.
Yoshioka T, Imura K, …, Horikawa T, Arimura A
J Invest Dermatol
2009 Mar
129
(3):714-22 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 4 Mar 2009
Nicotine activates TRPM5-dependent and independent taste pathways.
Oliveira-Maia AJ, Stapleton-Kotloski JR, …, Nicolelis MA, Simon SA
Proc Natl Acad Sci U S A
2009 Feb 3
106
(5):1596-601 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius / Robin Dando and Stephen Roper
Evaluated 4 Feb 2009
The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells.
Barbet G, Demion M, …, Kinet JP, Launay P
Nat Immunol
2008 Oct
9
(10):1148-56 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 2 Jan 2009
Rescue of volume-regulated anion current by bestrophin mutants with altered charge selectivity.
Chien LT, Hartzell HC
J Gen Physiol
2008 Nov
132
(5):537-46 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 10 Nov 2008
TMEM16A confers receptor-activated calcium-dependent chloride conductance.
Yang YD, Cho H, …, Shin YK, Oh U
Nature
2008 Oct 30
455
(7217):1210-5 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius / David Zenisek
Evaluated 25 Sep 2008
Pore region of TRPV3 ion channel is specifically required for heat activation.
Grandl J, Hu H, …, Petrus M, Patapoutian A
Nat Neurosci
2008 Aug 10 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Paul Garrity / Bernd Nilius
Evaluated 21 Aug 2008
General anesthetics activate a nociceptive ion channel to enhance pain and inflammation.
Matta JA, Cornett PM, …, Sahibzada N, Ahern GP
Proc Natl Acad Sci U S A
2008 Jun 24
105
(25):8784-9 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Gerald Zamponi / Bernd Nilius / Jaime García-Añoveros
Evaluated 23 Jul 2008
TRPM2-mediated Ca(2+) influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.
Yamamoto S, Shimizu S, …, Takeshima H, Mori Y
Nat Med
2008 Jun 8 [
abstract on PubMed
] [
related articles
] [
full text
]
Selected by
| Bernd Nilius
Evaluated 20 Jun 2008
A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating.
Myers BR, Bohlen CJ, Julius D
Neuron
2008 May 8
58
(3):362-73 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 23 May 2008
Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber).
Park TJ, Lu Y, …, Wilson SP, Lewin GR
PLoS Biol
2008 Jan
6
(1):e13 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius
Evaluated 25 Feb 2008
STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels.
Brandman O, Liou J, Park WS, Meyer T
Cell
2007 Dec 28
131
(7):1327-39 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Silvana Curci / Anjana Rao / Bernd Nilius / Anthony Means / Yuval Yarkoni and John Cambier
Evaluated 11 Jan 2008
Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels.
Leuner K, Kazanski V, …, Harteneck C, Müller WE
FASEB J
2007 Dec
21
(14):4101-11 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 12 Dec 2007
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Binshtok AM, Bean BP, Woolf CJ
Nature
2007 Oct 4
449
(7162):607-10 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius / Ian Hall / Michael Andresen / David Triggle / Gavril Pasternak / Emery Brown / Jaime García-Añoveros
Evaluated 12 Oct 2007
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani M, Siemens J, …, Julius D, Geppetti P
Proc Natl Acad Sci U S A
2007 Aug 14
104
(33):13519-24 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 17 Aug 2007
Requirement of a soluble intracellular factor for activation of transient receptor potential A1 by pungent chemicals: role of inorganic polyphosphates.
Kim D, Cavanaugh EJ
J Neurosci
2007 Jun 13
27
(24):6500-9 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 19 Jun 2007
Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease.
Leuenroth SJ, Okuhara D, …, Somlo S, Crews CM
Proc Natl Acad Sci U S A
2007 Mar 13
104
(11):4389-94 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius
Evaluated 27 Apr 2007
TRPC-like conductance mediates restoration of intracellular Ca2+ in cochlear outer hair cells in the guinea pig and rat.
Raybould NP, Jagger DJ, …, Cannell MB, Housley GD
J Physiol
2007 Feb 15
579
(Pt 1):101-13 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 21 Feb 2007
TRP channel activation by reversible covalent modification.
Hinman A, Chuang HH, Bautista DM, Julius D
Proc Natl Acad Sci U S A
2006 Dec 19
103
(51):19564-8 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius
Evaluated 23 Jan 2007
The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release.
Krapivinsky G, Mochida S, …, Cibulsky SM, Clapham DE
Neuron
2006 Nov 9
52
(3):485-96 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 21 Nov 2006
Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality.
Ciura S, Bourque CW
J Neurosci
2006 Aug 30
26
(35):9069-75 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius / Alastair Ferguson
Evaluated 3 Oct 2006
A voltage-gated proton-selective channel lacking the pore domain.
Ramsey IS, Moran MM, Chong JA, Clapham DE
Nature
2006 Apr 27
440
(7088):1213-6 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Michael Blatt / Bernd Nilius
Evaluated 6 Jun 2006
Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke.
Simard JM, Chen M, …, West GA, Gerzanich V
Nat Med
2006 Apr
12
(4):433-40 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 12 Apr 2006
Upregulated TRPC1 channel in vascular injury in vivo and its role in human neointimal hyperplasia.
Kumar B, Dreja K, …, Hellstrand P, Beech DJ
Circ Res
2006 Mar 3
98
(4):557-63 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius
Evaluated 10 Mar 2006
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.
Zhang SL, Yu Y, …, Stauderman KA, Cahalan MD
Nature
2005 Oct 6
437
(7060):902-5 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Annette Dolphin / Colin Taylor / Anjana Rao / Bernd Nilius
Evaluated 2 Feb 2006
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.
Chang Q, Hoefs S, …, Bindels RJ, Hoenderop JG
Science
2005 Oct 21
310
(5747):490-3 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Kermit Carraway / Bernd Nilius / Linda C. Hsieh-Wilson / Jens Leipziger
Evaluated 15 Dec 2005
A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.
Hermosura MC, Nayakanti H, …, Haymer DS, Garruto RM
Proc Natl Acad Sci U S A
2005 Aug 9
102
(32):11510-5 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius
Evaluated 17 Nov 2005
A possible unifying principle for mechanosensation.
Kung C
Nature
2005 Aug 4
436
(7051):647-54 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Bernd Nilius
Evaluated 29 Sep 2005
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor.
Murata Y, Iwasaki H, …, Inaba K, Okamura Y
Nature
2005 Jun 30
435
(7046):1239-43 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Annette Dolphin / Diane Papazian / Bernd Nilius / Angus Nairn / Dirk van Helden
Evaluated 18 Jul 2005
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain.
Rohács T, Lopes CM, Michailidis I, Logothetis DE
Nat Neurosci
2005 May
8
(5):626-34 [
abstract on PubMed
] [
related articles
] [
full text
] [
order article
]
Selected by
| Roger Hardie / Bernd Nilius
Evaluated 8 Jun 2005
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.
Moqrich A, Hwang SW, …, Story GM, Patapoutian A
Science
2005 Mar 4
307
(5714):1468-72 [
abstract on PubMed
] [
related articles
] [
FREE full text
]
Selected by
| Bernd Nilius
Evaluated 15 Apr 2005
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