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Kim Hughes
Department of Biological Science, Florida State University, United States of America

Faculty Member: Genomics & Genetics > Evolutionary/Comparative Genetics [ since 27 February 2004 ]
[ Evaluations ]
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Evaluations

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.
Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K
Cancer Res 2009 Oct 1 69(19):7507-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rose M Reynolds and Kim Hughes
Evaluated 20 Oct 2009

The genetic and environmental basis of adaptive differences in shoaling behaviour among populations of Trinidadian guppies, Poecilia reticulata.
Huizinga M, Ghalambor CK, Reznick DN
J Evol Biol 2009 Sep 22(9):1860-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rose M. Reynolds and Kim Hughes
Evaluated 19 Oct 2009

Immunogenic males: a genome-wide analysis of reproduction and the cost of mating in Drosophila melanogaster females.
Innocenti P, Morrow EH
J Evol Biol 2009 May 22(5):964-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Silvia Remolina and Kim Hughes
Evaluated 21 Aug 2009

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.
Pawlikowska L, Hu D, …, Ziv E, Study of Osteoporotic Fractures
Aging Cell 2009 Aug 8(4):460-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rose M. Reynolds and Kim Hughes
Evaluated 19 Aug 2009

Plasticity versus environmental canalization: population differences in thermal responses along a latitudinal gradient in Drosophila serrata.
Liefting M, Hoffmann AA, Ellers J
Evolution 2009 Aug 63(8):1954-63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rose M. Reynolds and Kim Hughes
Evaluated 19 Aug 2009

Adaptation to an extraordinary environment by evolution of phenotypic plasticity and genetic assimilation.
Lande R
J Evol Biol 2009 Jul 22(7):1435-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rose M. Reynolds and Kim Hughes
Evaluated 8 Jul 2009

Lifespan extension by dietary restriction is not linked to protection against somatic DNA damage in Drosophila melanogaster
Edman U, Garcia AM, Kapahi P, Vijg J
Aging Cell 2009 8:331-338 [full text]
Selected by | Rose M. Reynolds and Kim Hughes
Evaluated 8 Jul 2009

Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans.
Greer EL, Brunet A
Aging Cell 2009 Apr 8(2):113-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rose M. Reynolds and Kim Hughes
Evaluated 30 Apr 2009

Association of FOXO3A variation with human longevity confirmed in German centenarians.
Flachsbart F, Caliebe A, …, Schreiber S, Nebel A
Proc Natl Acad Sci U S A 2009 Feb 24 106(8):2700-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michele Ramsay / Rose M. Reynolds and Kim Hughes
Evaluated 30 Apr 2009

Systems genetics of complex traits in Drosophila melanogaster.
Ayroles JF, Carbone MA, …, Anholt RR, Mackay TF
Nat Genet 2009 Mar 41(3):299-307 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes / Andy Groves / David Rand
Evaluated 5 Mar 2009

Functional significance of allelic variation at methuselah, an aging gene in Drosophila.
Paaby AB, Schmidt PS
PLoS ONE 2008 3(4):e1987 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Hughes
Evaluated 1 May 2008

Lifespan and reproduction in Drosophila: New insights from nutritional geometry.
Lee KP, Simpson SJ, …, Soran N, Raubenheimer D
Proc Natl Acad Sci U S A 2008 Feb 19 105(7):2498-503 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes / Anthony Zera
Evaluated 5 Mar 2008


No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects.
Toivonen JM, Walker GA, …, Gems D, Partridge L
PLoS Genet 2007 Jun 3(6):e95 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurent Keller / Kim Hughes
Evaluated 28 Aug 2007

Regulation of Drosophila life span by olfaction and food-derived odors.
Libert S, Zwiener J, …, Roman G, Pletcher SD
Science 2007 Feb 23 315(5815):1133-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes / Thomas Nystrom
Evaluated 30 Mar 2007

Quantitative genomics of aggressive behavior in Drosophila melanogaster.
Edwards AC, Rollmann SM, Morgan TJ, Mackay TF
PLoS Genet 2006 Sep 15 2(9):e154 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Hughes
Evaluated 26 Oct 2006

Reproductive social behavior: cooperative games to replace sexual selection.
Roughgarden J, Oishi M, Akçay E
Science 2006 Feb 17 311(5763):965-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes / Priyanga Amarasekare
Evaluated 7 Mar 2006

Optimality and evolutionary tuning of the expression level of a protein.
Dekel E, Alon U
Nature 2005 Jul 28 436(7050):588-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes / Rebecca Kilner
Evaluated 15 Aug 2005

Premating, not postmating, barriers drive genetic dynamics in experimental hybrid populations of the endangered Sonoran topminnow.
Hurt CR, Farzin M, Hedrick PW
Genetics 2005 Oct 171(2):655-62 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Hughes
Evaluated 12 Aug 2005

The transcriptional consequences of mutation and natural selection in Caenorhabditis elegans.
Denver DR, Morris K, …, Lynch M, Thomas WK
Nat Genet 2005 May 37(5):544-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes / Magnus Nordborg
Evaluated 1 Jun 2005

The landscape of genetic complexity across 5,700 gene expression traits in yeast.
Brem RB, Kruglyak L
Proc Natl Acad Sci U S A 2005 Feb 1 102(5):1572-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Hughes / Thomas Mitchell-Olds / Joshua Plotkin
Evaluated 17 Mar 2005

Effect of extrinsic mortality on the evolution of senescence in guppies.
Reznick DN, Bryant MJ, …, Ghalambor CK, Ghalambor DE
Nature 2004 Oct 28 431(7012):1095-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laurent Keller / Kim Hughes
Evaluated 16 Mar 2005

High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome.
Denver DR, Morris K, Lynch M, Thomas WK
Nature 2004 Aug 5 430(7000):679-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes
Evaluated 8 Sep 2004

Mixed-model reanalysis of primate data suggests tissue and species biases in oligonucleotide-based gene expression profiles.
Hsieh WP, Chu TM, Wolfinger RD, Gibson G
Genetics 2003 Oct 165(2):747-57 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Hughes
Evaluated 16 Jul 2004

Quantitative trait loci affecting natural variation in Drosophila longevity.
Geiger-Thornsberry GL, Mackay TF
Mech Ageing Dev 2004 Mar 125(3):179-89 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Hughes
Evaluated 15 Jul 2004

Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan.
Parker JD, Parker KM, …, Sohal RS, Keller L
Proc Natl Acad Sci U S A 2004 Mar 9 101(10):3486-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Hughes
Evaluated 15 Apr 2004

Dopa decarboxylase (Ddc) affects variation in Drosophila longevity.
De Luca M, Roshina NV, …, Pasyukova EG, Mackay TF
Nat Genet 2003 Aug 34(4):429-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ralph Greenspan / Thomas Mitchell-Olds / Kim Hughes
Evaluated 8 Apr 2004

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