homefeedbacksupportlog on 14-Mar-2010 
  About F1000

 What is F1000?
 Key features
 How it's organized
 FAQs
 Faculties and sections
 Scope of sections
 Intl Advisory Board
 List of Faculty Members
 Associate Faculty Members
 The evaluation system
 Citing F1000
 Take a tour of the site
 Accessing fulltexts
 PubMed linkout
 How to subscribe
 Academic subscriptions
 Corporate subscriptions
 Try F1000 for free
 Who we are
 Media information
 Librarian resources
 Press releases
 In the press
 Developing countries
 F1000 Medicine
 Terms and conditions
 Privacy policy
 Contact us


Makoto Komiyama
Research Center for Advanced Science and Technology, University of Tokyo, Japan

Faculty Member: Chemical Biology > Biomimetic Chemistry [ since 29 June 2001 ]
[ Evaluations ]
to email [Help]
Evaluations

Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence.
Kuryavyi V, Patel DJ
Structure 2010 Jan 13 18(1):73-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 16 Feb 2010

In Vitro Recombination Mediated by G-Quadruplex.
Boán F, Gómez-Márquez J
Chembiochem 2009 Dec 14 [abstract on PubMed] [related articles] [full text]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 12 Jan 2010

Giardia Telomeric Sequence d(TAGGG)(4) Forms Two Intramolecular G-Quadruplexes in K(+) Solution: Effect of Loop Length and Sequence on the Folding Topology.
Hu L, Lim KW, Bouaziz S, Phan AT
J Am Chem Soc 2009 Oct 29 [abstract on PubMed] [related articles] [full text]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 6 Nov 2009

Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA.
Zheng KW, Chen Z, Hao YH, Tan Z
Nucleic Acids Res 2009 Oct 25 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 4 Nov 2009

Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands.
Palumbo SL, Ebbinghaus SW, Hurley LH
J Am Chem Soc 2009 Aug 12 131(31):10878-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 16 Sep 2009

An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae.
Cahoon LA, Seifert HS
Science 2009 Aug 7 325(5941):764-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 11 Aug 2009

G-quadruplex nucleic acids as therapeutic targets.
Balasubramanian S, Neidle S
Curr Opin Chem Biol 2009 Jun 8 [abstract on PubMed] [related articles] [full text]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 15 Jun 2009

The structures of quadruplex nucleic acids and their drug complexes.
Neidle S
Curr Opin Struct Biol 2009 May 30 [abstract on PubMed] [related articles] [full text]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 4 Jun 2009

Direct detection of abortive RNA transcripts in vivo.
Goldman SR, Ebright RH, Nickels BE
Science 2009 May 15 324(5929):927-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama / Katsu Murakami
Evaluated 19 May 2009

Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars.
Chang PV, Chen X, …, Bertozzi CR, Wu P
Angew Chem Int Ed Engl 2009 Apr 22 [abstract on PubMed] [related articles] [full text]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 1 May 2009

Local DNA topography correlates with functional noncoding regions of the human genome.
Parker SC, Hansen L, …, Tullius TD, Margulies EH
Science 2009 Apr 17 324(5925):389-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama / Megana Prasad and Andrew S McCallion / Jim Maher
Evaluated 31 Mar 2009

Self-sustained replication of an RNA enzyme.
Lincoln TA, Joyce GF
Science 2009 Feb 27 323(5918):1229-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Batey / Yan Xu and Makoto Komiyama / Andy Maule / Russ Hille
Evaluated 11 Mar 2009

Spliceosomal cleavage generates the 3' end of telomerase RNA.
Box JA, Bunch JT, Tang W, Baumann P
Nature 2008 Dec 18 456(7224):910-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama / Nick Rhind
Evaluated 2 Jan 2009

RNA toxicity is a component of ataxin-3 degeneration in Drosophila.
Li LB, Yu Z, Teng X, Bonini NM
Nature 2008 Jun 19 453(7198):1107-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 8 Dec 2008

Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates.
Paeschke K, Juranek S, …, Rhodes D, Lipps HJ
Nat Struct Mol Biol 2008 Jun 15(6):598-604 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 27 Nov 2008

G-Quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC.
Gros J, Guédin A, Mergny JL, Lacroix L
Chembiochem 2008 Sep 1 9(13):2075-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 20 Oct 2008

Effect of O6-methylguanine on the stability of G-quadruplex DNA.
Mekmaysy CS, Petraccone L, …, Trent JO, Chaires JB
J Am Chem Soc 2008 May 28 130(21):6710-1 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yan Xu and Makoto Komiyama
Evaluated 15 Jul 2008

Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.
Schoeftner S, Blasco MA
Nat Cell Biol 2008 Feb 10(2):228-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 29 Apr 2008

An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.
Kumari S, Bugaut A, Huppert JL, Balasubramanian S
Nat Chem Biol 2007 Apr 3(4):218-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ben Davis / Eric Westhof / Sabine Müller / Makoto Komiyama
Evaluated 29 Apr 2008

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Azzalin CM, Reichenbach P, …, Giulotto E, Lingner J
Science 2007 Nov 2 318(5851):798-801 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 18 Mar 2008

Positioning scission of single DNA molecules with nonspecific endonuclease based on nanomanipulation.
Li B, Zhang Y, …, Li MQ, Hu J
J Am Chem Soc 2007 May 30 129(21):6668-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 31 Aug 2007

The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution.
Xu Y, Noguchi Y, Sugiyama H
Bioorg Med Chem 2006 Aug 15 14(16):5584-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 23 Apr 2007

Cationic oligonucleotide-peptide conjugates with aggregating properties enter efficiently into cells while maintaining hybridization properties and enzymatic recognition.
Fraley AW, Pons B, …, Behr JP, Zuber G
J Am Chem Soc 2006 Aug 23 128(33):10763-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 6 Sep 2006

Sequencing genomes from single cells by polymerase cloning.
Zhang K, Martiny AC, …, Chisholm SW, Church GM
Nat Biotechnol 2006 Jun 24(6):680-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 20 Jun 2006

A mismatch-selective bifunctional rhodium-Oregon Green conjugate: a fluorescent probe for mismatched DNA.
Zeglis BM, Barton JK
J Am Chem Soc 2006 May 3 128(17):5654-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 12 Jun 2006

Template-directed DNA photoligation in rapid and selective detection of RNA point mutations.
Yoshimura Y, Noguchi Y, Sato H, Fujimoto K
Chembiochem 2006 Apr 7(4):598-601 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 19 Apr 2006

The incorporation of a photoisomerizable amino acid into proteins in E. coli.
Bose M, Groff D, …, Brustad E, Schultz PG
J Am Chem Soc 2006 Jan 18 128(2):388-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 18 Jan 2006

Cell-free cloning using phi29 DNA polymerase.
Hutchison CA, Smith HO, Pfannkoch C, Venter JC
Proc Natl Acad Sci U S A 2005 Nov 29 102(48):17332-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Makoto Komiyama
Evaluated 5 Dec 2005

Methyltransferase-directed DNA strand scission.
Comstock LR, Rajski SR
J Am Chem Soc 2005 Oct 19 127(41):14136-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 7 Nov 2005

DNA sequence-enabled reassembly of the green fluorescent protein.
Stains CI, Porter JR, …, Segal DJ, Ghosh I
J Am Chem Soc 2005 Aug 10 127(31):10782-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama / Larry McLaughlin
Evaluated 10 Aug 2005

Highly efficient endogenous human gene correction using designed zinc-finger nucleases.
Urnov FD, Miller JC, …, Gregory PD, Holmes MC
Nature 2005 Jun 2 435(7042):646-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barry Stoddard / John Cambier / Makoto Komiyama / Daniel Reines / Charles Coutelle
Evaluated 10 Jun 2005

Helix-forming properties of size-expanded DNA, an alternative four-base genetic form.
Liu H, Gao J, Kool ET
J Am Chem Soc 2005 Feb 9 127(5):1396-402 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 2 Mar 2005

Site-selective RNA cleavage by DNA bearing a base pair-mimic nucleoside.
Nakano S, Uotani Y, …, Fujii M, Sugimoto N
J Am Chem Soc 2005 Jan 19 127(2):518-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 20 Jan 2005

Sequence-selective and hydrolytic cleavage of DNA by zinc finger mutants.
Nomura A, Sugiura Y
J Am Chem Soc 2004 Dec 1 126(47):15374-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 2 Dec 2004

The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.
Xie J, Wang L, …, Spraggon G, Schultz PG
Nat Biotechnol 2004 Oct 22(10):1297-301 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fred Dyda / David Waugh / Makoto Komiyama / Mark Nelson
Evaluated 25 Nov 2004

5'-end SAGE for the analysis of transcriptional start sites.
Hashimoto S, Suzuki Y, …, Sugano S, Matsushima K
Nat Biotechnol 2004 Sep 22(9):1146-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John McPherson / Makoto Komiyama
Evaluated 17 Sep 2004

Circle-to-circle amplification for precise and sensitive DNA analysis.
Dahl F, Banér J, …, Landegren U, Nilsson M
Proc Natl Acad Sci U S A 2004 Mar 15 [abstract on PubMed] [related articles]
Selected by | Makoto Komiyama
Evaluated 2 Apr 2004

Sequence selective hydrolysis of linear DNA using conjugates of Zr(IV) complexes and peptide nucleic acids.
Zelder FH, Mokhir AA, Krämer R
Inorg Chem 2003 Dec 29 42(26):8618-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 23 Feb 2004

LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage.
Vester B, Lundberg LB, …, Douthwaite S, Wengel J
J Am Chem Soc 2002 Nov 20 124(46):13682-3 [abstract on PubMed] [related articles] [order article]
Selected by | Makoto Komiyama
Evaluated 23 Jan 2003

A continuous kinetic assay for RNA-cleaving deoxyribozymes, exploiting ethidium bromide as an extrinsic fluorescent probe.
Ferrari D, Peracchi A
Nucleic Acids Res 2002 Oct 15 30(20):e112 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Makoto Komiyama
Evaluated 2 Jan 2003

A monomeric red fluorescent protein.
Campbell RE, Tour O, …, Zacharias DA, Tsien RY
Proc Natl Acad Sci U S A 2002 Jun 11 99(12):7877-82 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ed Manser / Suresh Subramani / Atsushi Miyawaki / Makoto Komiyama
Evaluated 9 Oct 2002

Amplification of screening sensitivity through selective destruction: theory and screening of a library of carbonic anhydrase inhibitors.
Cheeseman JD, Corbett AD, …, Gleason JL, Kazlauskas RJ
J Am Chem Soc 2002 May 22 124(20):5692-701 [abstract on PubMed] [related articles] [order article]
Selected by | Morten Meldal / Makoto Komiyama / Dennis Hall / Anthony Czarnik
Evaluated 25 Jun 2002

Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase.
Xia G, Chen L, …, Schultz PG, Romesberg FE
Proc Natl Acad Sci U S A 2002 May 14 99(10):6597-602 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Makoto Komiyama / Niles Lehman
Evaluated 31 May 2002

Characterization of an RNA active site: interactions between a Diels-Alderase ribozyme and its substrates and products.
Stuhlmann F, Jäschke A
J Am Chem Soc 2002 Apr 3 124(13):3238-44 [abstract on PubMed] [related articles] [order article]
Selected by | Makoto Komiyama
Evaluated 13 May 2002

Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules.
Han M, Gao X, Su JZ, Nie S
Nat Biotechnol 2001 Jul 19(7):631-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Makoto Komiyama
Evaluated 19 Apr 2002

Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells.
Kuwabara T, Warashina M, …, Nakayama K, Taira K
Nucleic Acids Res 2001 Jul 1 29(13):2780-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Makoto Komiyama
Evaluated 7 Jan 2002

Single-molecule observation of protein-protein interactions in the chaperonin system.
Taguchi H, Ueno T, …, Yoshida M, Funatsu T
Nat Biotechnol 2001 Sep 19(9):861-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | W. E. Moerner / Makoto Komiyama / Kunihiro Kuwajima
Evaluated 19 Oct 2001

Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5' flanking region.
Xu XS, Glazer PM, Wang G
Gene 2000 Jan 25 242(1-2):219-28 [abstract on PubMed] [related articles] [order article]
Selected by | Makoto Komiyama
Evaluated 19 Oct 2001

^Top  Back to Faculty Members



© 1999-2010 Faculty of 1000 Ltd unless otherwise stated. < info@f1000.com >   Terms and conditions   Legal info