Faculty of 1000 Biology | Faculty member: Sarah O'Connor

15-Mar-2010

	Sarah O'Connor Department of Chemistry, Massachusetts Institute of Technology, United States of America
	Faculty Member: Chemical Biology > Biocatalysis [ since 20 April 2009 ]

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Evaluations

Selected by | Sarah O'Connor
Evaluated 15 Jan 2010

RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes.
Kempe K, Higashi Y, …, Sabarna K, Kutchan TM
Phytochemistry 2009 Mar 70(5):579-89 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sarah O'Connor
Evaluated 17 Jun 2009

Functional analysis of norcoclaurine synthase in Coptis japonica.
Minami H, Dubouzet E, Iwasa K, Sato F
J Biol Chem 2007 Mar 2 282(9):6274-82 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sarah O'Connor
Evaluated 7 Feb 2007

Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells.
Rischer H, Oresic M, …, Oksman-Caldentey KM, Goossens A
Proc Natl Acad Sci U S A 2006 Apr 4 103(14):5614-9 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Sarah O'Connor
Evaluated 11 Jul 2006

Selected by | Sarah O'Connor
Evaluated 22 May 2006

Selected by | Sarah O'Connor
Evaluated 5 Apr 2006

Design and evolution of new catalytic activity with an existing protein scaffold.
Park HS, Nam SH, …, Benkovic SJ, Kim HS
Science 2006 Jan 27 311(5760):535-8 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Reinhard Sterner / Burckhard Seelig / Sarah O'Connor
Evaluated 8 Feb 2006

Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked.
Bhatt A, Stark CB, …, Staunton J, Leadlay PF
Angew Chem Int Ed Engl 2005 Nov 4 44(43):7075-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Cane / Sarah O'Connor
Evaluated 27 Oct 2005

Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases.
Siskos AP, Baerga-Ortiz A, …, Weissman KJ, Leadlay PF
Chem Biol 2005 Oct 12(10):1145-53 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sarah O'Connor
Evaluated 27 Oct 2005

Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
Kuzuyama T, Noel JP, Richard SB
Nature 2005 Jun 16 435(7044):983-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Haruo Seto / Sarah O'Connor
Evaluated 18 Aug 2005

Structure of the Bacillus subtilis quorum-sensing peptide pheromone ComX.
Okada M, Sato I, …, Dubnau D, Sakagami Y
Nat Chem Biol 2005 Jun 1(1):23-4 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sarah O'Connor / Padmanabhan Balaram
Evaluated 1 Jun 2005

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.
Zazopoulos E, Huang K, …, Shen B, Farnet CM
Nat Biotechnol 2003 Feb 21(2):187-90 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Sarah O'Connor
Evaluated 6 Apr 2005

Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei.
Piel J, Hui D, …, Fusetani N, Matsunaga S
Proc Natl Acad Sci U S A 2004 Nov 16 101(46):16222-7 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Tadeusz Molinski / Leo Eberl / Sarah O'Connor
Evaluated 6 Apr 2005