homefeedbacksupportlog on 21-Mar-2010 
  About F1000

 What is F1000?
 Key features
 How it's organized
 FAQs
 Faculties and sections
 Scope of sections
 Intl Advisory Board
 List of Faculty Members
 Associate Faculty Members
 The evaluation system
 Citing F1000
 Take a tour of the site
 Accessing fulltexts
 PubMed linkout
 How to subscribe
 Academic subscriptions
 Corporate subscriptions
 Try F1000 for free
 Who we are
 Media information
 Librarian resources
 Press releases
 In the press
 Developing countries
 F1000 Medicine
 Terms and conditions
 Privacy policy
 Contact us


James Duffin
Department of Physiology & Anaesthesia, University of Toronto, Toronto, Canada

Faculty Member: Physiology > Integrative Physiology [ since 15 March 2005 ]
[ Homepage ] [ Evaluations ]
Home page

http://www.utoronto.ca/neurosci/faculty/duffin.html

to email [Help]
Evaluations

Repeated inspiratory occlusions in anesthetized rats acutely increase blood coagulability as assessed by thromboelastography.
Othman M, Gordon SP, Iscoe S
Respir Physiol Neurobiol 2010 Jan 25 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 1 Mar 2010

Influence of high altitude on cerebrovascular responsiveness to CO2.
Fan JL, Burgess KR, …, Cotter JD, Ainslie PN
J Physiol 2009 Dec 21 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 27 Jan 2010

Spinal adenosine 2A receptor inhibition enhances phrenic long term facilitation following acute intermittent hypoxia.
Hoffman MS, Golder FJ, Mahamed S, Mitchell GS
J Physiol 2009 Nov 9 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 23 Dec 2009

Progressive augmentation and ventilatory long-term facilitation are enhanced in sleep apnoea patients and are mitigated by antioxidant administration.
Lee DS, Badr MS, Mateika JH
J Physiol 2009 Nov 15 587(Pt 22):5451-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 18 Nov 2009

Stabilizing immature breathing patterns of preterm infants using stochastic mechanosensory stimulation.
Bloch-Salisbury E, Indic P, Bednarek F, Paydarfar D
J Appl Physiol 2009 Oct 107(4):1017-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 21 Oct 2009

Caffeine in the neonatal period induces long-lasting changes in sleep and breathing in adult rats.
Montandon G, Horner RL, Kinkead R, Bairam A
J Physiol 2009 Sep 21 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 25 Sep 2009

Learning to breathe: A shift in the control of the inspiratory-expiratory phase transition from sensory- to centrally-dominated mechanisms during postnatal development in rats.
Dutschmann M, Moerschel M, Rybak IA, Dick TE
J Physiol 2009 Aug 24 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 27 Aug 2009

Comparison of the metabolic and ventilatory response to hypoxia and H2S in unsedated mice and rats.
Haouzi P, Bell HJ, Notet V, Bihain B
Respir Physiol Neurobiol 2009 Jul 31 167(3):316-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 13 Aug 2009

The brainstem respiratory network: An overview of a half century of research.
Bianchi AL, Gestreau C
Respir Physiol Neurobiol 2009 May 3 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 10 Jul 2009

Hypercapnic vs. hypoxic control of cardiovascular, cardiovagal, and sympathetic function.
Steinback CD, Salzer D, …, Kowalchuk J, Shoemaker JK
Am J Physiol Regul Integr Comp Physiol 2009 Feb 296(2):R402-10 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 8 Jun 2009

Opioid receptor mechanisms at the hypoglossal motor pool and effects on tongue muscle activity in vivo.
Hajiha M, Dubord MA, Liu H, Horner RL
J Physiol 2009 Jun 1 587(Pt 11):2677-2692 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 2 Jun 2009


Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness.
Dias MB, Li A, Nattie EE
J Physiol 2009 May 1 587(Pt 9):2059-67 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 5 May 2009

Long-term facilitation of upper airway muscle activity induced by episodic upper airway negative pressure and hypoxia in spontaneously breathing anaesthetised rats.
Ryan S, Nolan P
J Physiol 2009 Mar 30 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 20 Apr 2009

Contribution of the Carotid Body Chemoreceptors to Eupneic Ventilation in the Intact, Unanesthetized Dog.
Blain GM, Smith CA, Henderson KS, Dempsey JA
J Appl Physiol 2009 Feb 26 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 17 Mar 2009

Intermittent hypoxia and respiratory plasticity in humans and other animals: does exposure to intermittent hypoxia promote or mitigate sleep apnoea?
Mateika JH, Narwani G
Exp Physiol 2009 Mar 94(3):279-96 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 5 Mar 2009

Lateral parabrachial nucleus mediates shortening of expiration and increase of inspiratory drive during hypercapnia.
Song G, Poon CS
Respir Physiol Neurobiol 2009 Jan 1 165(1):9-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 3 Feb 2009

A negative interaction between brainstem and peripheral respiratory chemoreceptors modulates peripheral chemoreflex magnitude.
Day TA, Wilson RJ
J Physiol 2008 Dec 22 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 7 Jan 2009

Cardiorespiratory and cerebrovascular responses to hyperoxic and hypoxic rebreathing: effects of acclimatization to high altitude.
Ainslie PN, Burgess KR
Respir Physiol Neurobiol 2008 Apr 30 161(2):201-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 24 Nov 2008

Reconfiguration of respiratory-related population activity in a rostrally tilted transversal slice preparation following blockade of inhibitory neurotransmission in neonatal rats.
Funke F, Müller M, Dutschmann M
Pflugers Arch 2008 Oct 457(1):185-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 24 Nov 2008

Harvey Cushing and the regulation of blood pressure in giraffe, rats and man: introducing Cushing's mechanism.
Paton JF, Dickinson CJ, Mitchell G
Exp Physiol 2008 Sep 26 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 14 Oct 2008

Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway.
Gourine AV, Dale N, …, Huckstepp R, Spyer KM
J Physiol 2008 Aug 15 586(16):3963-78 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin / Yves Jammes
Evaluated 22 Aug 2008

Altered gravity highlights Central Pattern Generator mechanisms.
White O, Bleyenheuft Y, …, Thonnard JL, Lefevre P
J Neurophysiol 2008 Jul 23 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 6 Aug 2008

Adaptation and mal-adaptation to ambient hypoxia; Andean, Ethiopian and Himalayan patterns.
Xing G, Qualls C, …, Verma A, Appenzeller O
PLoS ONE 2008 3(6):e2342 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 11 Jun 2008

Spatiotemporal organization of frog respiratory neurons visualized on the ventral medullary surface.
Oku Y, Kimura N, Masumiya H, Okada Y
Respir Physiol Neurobiol 2008 May 31 161(3):281-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 20 May 2008

Selective Reduction of Blood Flow to White Matter During Hypercapnia Corresponds With Leukoaraiosis.
Mandell DM, Han JS, …, Fisher JA, Mikulis DJ
Stroke 2008 May 1 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 13 May 2008

Cerebrovascular responses to hypoxia and hypocapnia in Ethiopian high altitude dwellers.
Claydon VE, Gulli G, …, Gebremedhin A, Hainsworth R
Stroke 2008 Feb 39(2):336-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 8 May 2008

Comparing the lactate and EMG thresholds of recreational cyclists during incremental pedaling exercise.
Candotti CT, Loss JF, …, de Oliveira JL, de Oliveira LP
Can J Physiol Pharmacol 2008 May 86(5):272-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 28 Apr 2008

Eupnea of in situ rats persists following blockers of in vitro pacemaker burster activities.
St-John WM
Respir Physiol Neurobiol 2008 Feb 29 160(3):353-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 5 Mar 2008

Breathing frequency changes at the onset of stepping in human infants.
Noah JA, Boliek CA, Lam T, Yang JF
J Neurophysiol 2008 Jan 9 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 18 Feb 2008

COMPARATIVE ANALYSIS OF NEONATAL AND ADULT RAT CAROTID BODY RESPONSES TO CHRONIC INTERMITTENT HYPOXIA.
Pawar A, Peng YJ, Jacono FJ, Prabhakar NR
J Appl Physiol 2008 Jan 10 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 16 Jan 2008


Ventilatory long-term facilitation in mice can be observed both during sleep and wake periods and depends on orexin.
Terada J, Nakamura A, …, Fukuda Y, Kuwaki T
J Appl Physiol 2007 Nov 21 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 10 Dec 2007

Spatial and functional architecture of the Mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms.
Smith JC, Abdala AP, …, Rybak IA, Paton JF
J Neurophysiol 2007 Dec 98(6):3370-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 22 Oct 2007

Postnatal developmental changes in activation profiles of the respiratory neuronal network in the rat ventral medulla.
Oku Y, Masumiya H, Okada Y
J Physiol 2007 Nov 15 585(Pt 1):175-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 28 Sep 2007

Peripheral oxygen-sensing cells directly modulate the output of an identified respiratory central pattern generating neuron.
Bell HJ, Inoue T, …, Luk C, Syed NI
Eur J Neurosci 2007 Jun 25(12):3537-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 31 Aug 2007

Human cerebrovascular and ventilatory CO2 reactivity to end-tidal, arterial and internal jugular vein PCO2.
Peebles K, Celi L, …, Thomas K, Ainslie PN
J Physiol 2007 Oct 1 584(Pt 1):347-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 28 Aug 2007

The effects of hypo- and hyperglycaemia on the hypoxic ventilatory response in humans.
Ward DS, Voter WA, Karan S
J Physiol 2007 Jul 15 582(Pt 2):859-69 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 19 Jul 2007


Is there a link between intermittent hypoxia-induced respiratory plasticity and obstructive sleep apnoea?
Mahamed S, Mitchell GS
Exp Physiol 2007 Jan 92(1):27-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 14 Jun 2007

Cardiorespiratory failure in rat induced by severe inspiratory resistive loading.
Simpson JA, Iscoe S
J Appl Physiol 2007 Apr 102(4):1556-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 12 Apr 2007

Carotid body chemosensory activity and ventilatory chemoreflexes in cats persist after combined cholinergic-purinergic block.
Reyes EP, Fernández R, Larraín C, Zapata P
Respir Physiol Neurobiol 2007 Apr 16 156(1):23-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 14 Mar 2007

The influence of inspiratory and expiratory muscle training upon rowing performance.
Griffiths LA, McConnell AK
Eur J Appl Physiol 2007 Mar 99(5):457-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 16 Jan 2007

Identifying cardiorespiratory neurocircuitry involved in central command during exercise in humans.
Green AL, Wang S, …, Aziz TZ, Paterson DJ
J Physiol 2007 Jan 15 578(Pt 2):605-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 4 Dec 2006

Optical imaging of medullary ventral respiratory network during eupnea and gasping in situ.
Potts JT, Paton JF
Eur J Neurosci 2006-06-01 23(11):3025-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 30 Oct 2006

Influence of cerebrovascular function on the hypercapnic ventilatory response in healthy humans.
Xie A, Skatrud JB, …, Lin J, Dempsey JA
J Physiol 2006 Nov 15 577(Pt 1):319-29 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 1 Sep 2006

Nonassociative learning as gated neural integrator and differentiator in stimulus-response pathways.
Poon CS, Young DL
Behav Brain Funct 2006 2:29 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 1 Sep 2006

Simultaneous inhibition of caudal medullary raphe and retrotrapezoid nucleus decreases breathing and the CO2 response in conscious rats.
Li A, Zhou S, Nattie E
J Physiol 2006 Nov 15 577(Pt 1):307-18 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 13 Jul 2006

Changes in respiratory-modulated neural activities, consistent with obstructive and central apnea, during fictive seizures in an in situ anaesthetized rat preparation.
St-John WM, Rudkin AH, Homes GL, Leiter JC
Epilepsy Res 2006 Aug 70(2-3):218-28 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 4 Jul 2006

Neurosteroid modulation of respiratory rhythm in rats during the perinatal period.
Ren J, Greer JJ
J Physiol 2006 Jul 15 574(Pt 2):535-46 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 19 Jun 2006

Effects of femoral vascular occlusion on ventilatory responses during recovery from exercise in human.
Fukuba Y, Kitano A, …, Endo MY, Miura A
Respir Physiol Neurobiol 2007 Jan 15 155(1):29-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 12 Jun 2006

Long-term facilitation of ventilation and genioglossus muscle activity is evident in the presence of elevated levels of carbon dioxide in awake humans.
Harris DP, Balasubramaniam A, Badr MS, Mateika JH
Am J Physiol Regul Integr Comp Physiol 2006 Oct 291(4):R1111-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 25 May 2006

Development and pH sensitivity of the respiratory rhythm of fetal mice in vitro.
Eugenín J, von Bernhardi R, Muller KJ, Llona I
Neuroscience 2006 Aug 11 141(1):223-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 17 May 2006

Gasping activity in vitro: a rhythm dependent on 5-HT2A receptors.
Tryba AK, Peña F, Ramirez JM
J Neurosci 2006 Mar 8 26(10):2623-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 26 Apr 2006

Dynamic changes in glottal resistance during exposure to severe hypoxia in neonatal rats in situ.
Dutschmann M, Paton JF
Pediatr Res 2005 Aug 58(2):193-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 10 Feb 2006

Effects of electrical stimulation of the medullary raphe nuclei on respiratory movement in rats.
Cao Y, Fujito Y, Matsuyama K, Aoki M
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2006 May 192(5):497-505 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 10 Feb 2006

Optical recording from respiratory pattern generator of fetal mouse brainstem reveals a distributed network.
Eugenin J, Nicholls JG, Cohen LB, Muller KJ
Neuroscience 2006 137(4):1221-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 5 Jan 2006

Sympathetic neural outflow and chemoreflex sensitivity are related to spontaneous breathing rate in normal men.
Narkiewicz K, van de Borne P, …, Kara T, Somers VK
Hypertension 2006 Jan 47(1):51-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 5 Jan 2006

Characterisation of c-Fos expression in the central nervous system of mice following right atrial injections of the 5-HT3 receptor agonist phenylbiguanide.
de Vries A, Paton JF, Lightman SL, Lowry CA
Auton Neurosci 2005 Dec 30 123(1-2):62-75 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 5 Dec 2005

Specific carotid body chemostimulation is sufficient to elicit phrenic poststimulus frequency decline in a novel in situ dual-perfused rat preparation.
Day TA, Wilson RJ
Am J Physiol Regul Integr Comp Physiol 2005 Aug 289(2):R532-R544 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 17 Nov 2005

The ventilatory response to carbon dioxide and sustained hypoxia is enhanced after episodic hypoxia in OSA patients.
Khodadadeh B, Badr MS, Mateika JH
Respir Physiol Neurobiol 2006 Feb 28 150(2-3):122-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 19 Aug 2005

Fluorescent tagging of rhythmically active respiratory neurons within the pre-Bötzinger complex of rat medullary slice preparations.
Pagliardini S, Adachi T, …, Funk GD, Greer JJ
J Neurosci 2005 Mar 9 25(10):2591-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 2 Aug 2005

Kv1.1 deletion augments the afferent hypoxic chemosensory pathway and respiration.
Kline DD, Buniel MC, …, Prabhakar NR, Kunze DL
J Neurosci 2005 Mar 30 25(13):3389-99 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 2 Jun 2005

Ancient gill and lung oscillators may generate the respiratory rhythm of frogs and rats.
Vasilakos K, Wilson RJ, Kimura N, Remmers JE
J Neurobiol 2005 Feb 15 62(3):369-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Duffin
Evaluated 29 Apr 2005

Arterial pulse modulated activity is expressed in respiratory neural output.
Dick TE, Shannon R, …, Baekey DM, Morris KF
J Appl Physiol 2005 Aug 99(2):691-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Duffin
Evaluated 24 Mar 2005

^Top  Back to Faculty Members


© 1999-2010 Faculty of 1000 Ltd unless otherwise stated. < info@f1000.com >   Terms and conditions   Legal info