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Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells.
Kim JY, Han EH, …, Lee KY, Jeong HG
Toxicol Lett 2010 Mar 15 193(2):200-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin van den Berg
Evaluated 15 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
 Control of female gamete formation by a small RNA pathway in Arabidopsis.
Olmedo-Monfil V, Durán-Figueroa N, …, Martienssen RA, Vielle-Calzada JP
Nature 2010 Mar 7 [abstract on PubMed] [related articles] [full text]
Selected by | Elizabeth Dennis
Evaluated 15 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
Tech Advance
 Pathway of ATP utilization and duplex rRNA unwinding by the DEAD-box helicase, DbpA.
Henn A, Cao W, …, Hackney DD, De La Cruz EM
Proc Natl Acad Sci U S A 2010 Mar 2 107(9):4046-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kathleen Hall
Evaluated 15 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
 The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.
Kim S, Wairkar YP, Daniels RW, Diantonio A
J Cell Biol 2010 Mar 8 188(5):717-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anne Spang
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
 Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.
Lichtenberger BM, Tan PK, …, Petzelbauer P, Sibilia M
Cell 2010 Jan 22 140(2):268-79 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arthur Mercurio
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Tech Advance
 A rapid and robust assay for detection of S-phase cell cycle progression in plant cells and tissues by using ethynyl deoxyuridine.
Kotogány E, Dudits D, Horváth GV, Ayaydin F
Plant Methods 2010 6(1):5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lieven De Veylder
Evaluated 15 Mar 2010

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F1000 Factor 3.0

New Finding
 Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells.
Greber B, Wu G, …, Tesar P, Schöler HR
Cell Stem Cell 2010 Mar 5 6(3):215-226 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patrick Tam
Evaluated 15 Mar 2010

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F1000 Factor 3.0

Hypothesis
New Finding
 Missense Mutations in the Copper Transporter Gene ATP7A Cause X-Linked Distal Hereditary Motor Neuropathy.
Kennerson ML, Nicholson GA, …, Shy ME, Garbern JY
Am J Hum Genet 2010 Mar 12 86(3):343-352 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Antonellis
Evaluated 15 Mar 2010

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F1000 Factor 6.0

Hypothesis
New Finding
 Stat3 promotes directional cell migration by regulating Rac1 activity via its activator betaPIX.
Teng TS, Lin B, …, Ng DC, Cao X
J Cell Sci 2009 Nov 15 122(Pt 22):4150-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Lockett
Evaluated 15 Mar 2010

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F1000 Factor 3.0

New Finding
Novel Drug Target
 Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.
Harmon GS, Dumlao DS, …, Dong H, Glass CK
Nat Med 2010 Mar 16(3):313-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William H Colledge
Evaluated 15 Mar 2010


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