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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Transferrin therapy ameliorates disease in beta-thalassemic mice.
Li H, Rybicki AC, …, Fabry ME, Ginzburg YZ
Nat Med 2010 Feb 16(2):177-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas W von Geldern
Evaluated 8 Sep 2010

Must Read
F1000 Factor 6.0

New Finding
Structural basis for negative cooperativity in growth factor binding to an EGF receptor.
Alvarado D, Klein DE, Lemmon MA
Cell 2010 Aug 20 142(4):568-79 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arthur Christopoulos
Evaluated 8 Sep 2010

Recommended
F1000 Factor 3.0

New Finding
The association of olanzapine-induced weight gain with peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism in patients with schizophrenia.
Herken H, Erdal M, …, Barlas O, Akin F
DNA Cell Biol 2009 Oct 28(10):515-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Julia Stäker and Werner Steimer
Evaluated 8 Sep 2010

Must Read
F1000 Factor 6.0

New Finding
Myosin II contributes to cell-scale actin network treadmilling through network disassembly.
Wilson CA, Tsuchida MA, …, Danuser G, Theriot JA
Nature 2010 May 20 465(7296):373-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Frank Nelson and Kevin Conley
Evaluated 8 Sep 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Human mucosal associated invariant T cells detect bacterially infected cells.
Gold MC, Cerri S, …, Hansen TH, Lewinsohn DM
PLoS Biol 2010 8(6):e1000407 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Annemieke de Jong and David Branch Moody
Evaluated 8 Sep 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Condensins promote chromosome recoiling during early anaphase to complete sister chromatid separation.
Renshaw MJ, Ward JJ, …, Nédélec FJ, Tanaka TU
Dev Cell 2010 Aug 17 19(2):232-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kerry Bloom
Evaluated 8 Sep 2010

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.
Wada T, Ishiwata K, …, Watanabe N, Karasuyama H
J Clin Invest 2010 Aug 2 120(8):2867-75 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Shinsuke Taki
Evaluated 8 Sep 2010

Recommended
F1000 Factor 3.0

New Finding
TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability.
Mieulet V, Yan L, …, Moinard C, Lamb RF
Sci Signal 2010 Aug 3(135):ra61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Tsichlis
Evaluated 8 Sep 2010

Recommended
F1000 Factor 3.0

Confirmation
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia.
Niemeyer CM, Kang MW, …, Flotho C, Loh ML
Nat Genet 2010 Sep 42(9):794-800 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giovanni Neri
Evaluated 8 Sep 2010

Must Read
F1000 Factor 6.0

New Finding
CaMKII control of spine size and synaptic strength: role of phosphorylation states and nonenzymatic action.
Pi HJ, Otmakhov N, …, De Koninck P, Lisman J
Proc Natl Acad Sci U S A 2010 Aug 10 107(32):14437-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Johannes Hell
Evaluated 8 Sep 2010


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