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Must Read
F1000 Factor 6.0

New Finding
Basal forebrain activation enhances cortical coding of natural scenes.
Goard M, Dan Y
Nat Neurosci 2009 Nov 12(11):1444-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tim Kietzmann and Peter König
Evaluated 20 Nov 2009

Recommended
F1000 Factor 3.0

Confirmation
Assessment of the effects of physical training in patients with chronic heart failure: the utility of effort-independent exercise variables.
Kemps HM, de Vries WR, …, Thijssen EJ, Schep G
Eur J Appl Physiol 2009 Oct 16 [abstract on PubMed] [related articles] [full text]
Selected by | Yves Jammes
Evaluated 20 Nov 2009

Must Read
F1000 Factor 6.0

New Finding
CLIP-170-dependent capture of membrane organelles by microtubules initiates minus-end directed transport.
Lomakin AJ, Semenova I, …, Akhmanova A, Rodionov V
Dev Cell 2009 Sep 17(3):323-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jeffrey Axelrod
Evaluated 20 Nov 2009

Recommended
F1000 Factor 3.0

New Finding
Novel Drug Target
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6.
Fiesel FC, Voigt A, …, Schulz JB, Kahle PJ
EMBO J 2009 Nov 12 [abstract on PubMed] [related articles] [full text]
Selected by | Orly Reiner
Evaluated 20 Nov 2009

Must Read
F1000 Factor 6.0

New Finding
Autophagy induction by the pathogen receptor CD46.
Joubert PE, Meiffren G, …, Rabourdin-Combe C, Faure M
Cell Host Microbe 2009 Oct 22 6(4):354-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carolyn Coyne
Evaluated 20 Nov 2009

Must Read
F1000 Factor 6.0

Hypothesis
Controversial
Reactome array: forging a link between metabolome and genome.
Beloqui A, Guazzaroni ME, …, Golyshin PN, Ferrer M
Science 2009 Oct 9 326(5950):252-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ben Davis
Evaluated 20 Nov 2009

Must Read
F1000 Factor 6.0

Controversial
Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus.
McGuire HM, Vogelzang A, …, Sprent J, King C
Proc Natl Acad Sci U S A 2009 Oct 30 [abstract on PubMed] [related articles] [full text]
Selected by | Pablo Silveira and Antony Basten
Evaluated 20 Nov 2009

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.
Tang BC, Dawson M, …, Fu J, Hanes J
Proc Natl Acad Sci U S A 2009 Nov 9 106 [abstract on PubMed] [related articles] [full text]
Selected by | William H Colledge
Evaluated 20 Nov 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Tech Advance
Profiling translatomes of discrete cell populations resolves altered cellular priorities during hypoxia in Arabidopsis.
Mustroph A, Zanetti ME, …, Girke T, Bailey-Serres J
Proc Natl Acad Sci U S A 2009 Nov 3 106(44):18843-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mikael Brosché and Christiaan van der Schoot
Evaluated 20 Nov 2009

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins.
Schrank TP, Bolen DW, Hilser VJ
Proc Natl Acad Sci U S A 2009 Oct 6 106(40):16984-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Van Doren
Evaluated 20 Nov 2009


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