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Top 10 / All time Top 10 / Most viewed / Hidden jewels		Page 1 of 282. Select Page: 1 2 3 4 5 6 7 8 9 10 >>
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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Novel Drug Target
 Vitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation.
Fu M, Sato Y, …, Napoli JL, Heuckeroth RO
Development 2010 Feb 137(4):631-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Judith S Eisen
Evaluated 9 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Energized outer membrane and spatial separation of metabolic processes in the hyperthermophilic Archaeon Ignicoccus hospitalis.
Küper U, Meyer C, …, Rachel R, Huber H
Proc Natl Acad Sci U S A 2010 Feb 1 [abstract on PubMed] [related articles] [full text]
Selected by | Roy Gross
Evaluated 9 Feb 2010

Must Read
F1000 Factor 6.0

Confirmation
New Finding
 Control of heart rate by cAMP sensitivity of HCN channels.
Alig J, Marger L, …, Mangoni ME, Isbrandt D
Proc Natl Acad Sci U S A 2009 Jul 21 106(29):12189-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mohammad Shariq Imtiaz and Dirk van Helden
Evaluated 9 Feb 2010

Exceptional
F1000 Factor 9.0

New Finding
 PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice.
Baudat F, Buard J, …, Coop G, de Massy B
Science 2009 Dec 31 [abstract on PubMed] [related articles] [full text]
Selected by | Laurie Stevison and Mohamed Noor
Evaluated 9 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Annotation error in public databases: misannotation of molecular function in enzyme superfamilies.
Schnoes AM, Brown SD, Dodevski I, Babbitt PC
PLoS Comput Biol 2009 Dec 5(12):e1000605 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew Hahn
Evaluated 9 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
 Origins and functional impact of copy number variation in the human genome.
Conrad DF, Pinto D, …, Scherer SW, Hurles ME
Nature 2009 Oct 7 [abstract on PubMed] [related articles] [full text]
Selected by | R Frank Kooy
Evaluated 9 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I.
Puel A, Döffinger R, …, Lilic D, Casanova JL
J Exp Med 2010 Feb 1 [abstract on PubMed] [related articles] [full text]
Selected by | Caetano Reis e Sousa
Evaluated 8 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines.
Kisand K, Bøe Wolff AS, …, Willcox N, Meager A
J Exp Med 2010 Feb 1 [abstract on PubMed] [related articles] [full text]
Selected by | Caetano Reis e Sousa
Evaluated 8 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Vinculin regulates cell-surface E-cadherin expression by binding to {beta}-catenin.
Peng X, Cuff LE, Lawton CD, Demali KA
J Cell Sci 2010 Jan 19 [abstract on PubMed] [related articles] [full text]
Selected by | Ronen Zaidel-Bar
Evaluated 8 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis.
Wang Q, Uhlirova M, Bohmann D
Dev Cell 2010 18:157-64 [full text]
Selected by | Talila Volk
Evaluated 8 Feb 2010


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