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F1000 Factor 6.0

New Finding
 The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity.
Neau DB, Gilbert NC, …, Brash AR, Newcomer ME
Biochemistry 2009 Aug 25 48(33):7906-15 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ivo Feussner
Evaluated 27 Nov 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Membrane proteins Bqt3 and -4 anchor telomeres to the nuclear envelope to ensure chromosomal bouquet formation.
Yuji Y, Yamane M, …, Haraguchi T, Hiraoka Y
J Cell Biol 2009 187:413-27 [full text]
Selected by | Kazunori Tomita and Julie Cooper
Evaluated 27 Nov 2009

Recommended
F1000 Factor 3.0

New Finding
 A pH-responsive riboregulator.
Nechooshtan G, Elgrably-Weiss M, …, Westhof E, Altuvia S
Genes Dev 2009 Nov 15 23(22):2650-62 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Batey
Evaluated 27 Nov 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Dynamic refolding of IFN-gamma mRNA enables it to function as PKR activator and translation template.
Cohen-Chalamish S, Hasson A, …, Osman F, Kaempfer R
Nat Chem Biol 2009 Dec 5(12):896-903 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Batey
Evaluated 27 Nov 2009

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
 Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay.
Kerényi Z, Mérai Z, …, Nagy F, Silhavy D
EMBO J 2008 Jun 4 27(11):1585-95 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laura Trinkle-Mulcahy
Evaluated 27 Nov 2009

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F1000 Factor 3.0

Hypothesis
New Finding
 Aberrant mRNA transcripts and the nonsense-mediated decay proteins UPF2 and UPF3 are enriched in the Arabidopsis nucleolus.
Kim SH, Koroleva OA, …, Shaw PJ, Brown JW
Plant Cell 2009 Jul 21(7):2045-57 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laura Trinkle-Mulcahy
Evaluated 27 Nov 2009

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F1000 Factor 3.0

New Finding
 Copy number variations in three children with sudden infant death.
Toruner GA, Kurvathi R, …, Schwalb MN, Wallerstein R
Clin Genet 2009 Jul 76(1):63-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yiping Shen and James Gusella
Evaluated 27 Nov 2009

Recommended
F1000 Factor 3.0

New Finding
 p53-dependent translational control of senescence and transformation via 4E-BPs.
Petroulakis E, Parsyan A, …, Teodoro JG, Sonenberg N
Cancer Cell 2009 Nov 6 16(5):439-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Proud
Evaluated 27 Nov 2009

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F1000 Factor 3.0

New Finding
Tech Advance
 Magnetic resonance imaging of hypoxic injury to the murine placenta.
Tomlinson TM, Garbow JR, …, Nelson DM, Sadovsky Y
Am J Physiol Regul Integr Comp Physiol 2009 Nov 18 [abstract on PubMed] [related articles] [full text]
Selected by | Nick Illsley
Evaluated 27 Nov 2009

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F1000 Factor 3.0

New Finding
 Homology of dipteran bristles and lepidopteran scales: requirement for the Bombyx mori achaete-scute homologue ASH2.
Zhou Q, Yu L, …, Yi Y, Zhang Z
Genetics 2009 Oct 183(2):619-27, 1SI-3SI [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patricia Simpson
Evaluated 26 Nov 2009


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