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Recommended
F1000 Factor 3.0

New Finding
Salicylic acid stimulates secretion of the normally symplastic enzyme mannitol dehydrogenase: a possible defense against mannitol-secreting fungal pathogens.
Cheng FY, Zamski E, …, Pharr DM, Williamson JD
Planta 2009 Nov 230(6):1093-103 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Huber
Evaluated 19 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux.
Wang Q, Zhang Y, …, Zhao S, Zhao GP
Science 2010 Feb 19 327(5968):1004-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Adrian Mehlitz and Roy Gross
Evaluated 19 Mar 2010

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Tech Advance
Loss of Aip1 reveals a role in maintaining the actin monomer pool and an in vivo oligomer assembly pathway.
Okreglak V, Drubin DG
J Cell Biol 2010 Mar 15 [abstract on PubMed] [related articles] [full text]
Selected by | Pekka Lappalainen
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Tech Advance
Characterization of a Novel LysM Domain from Lactobacillus fermentum Bacteriophage Endolysin and Its Use as an Anchor to Display Heterologous Proteins on the Surface of Lactic Acid Bacteria.
Hu S, Kong J, …, Guo T, Ji M
Appl Environ Microbiol 2010 Feb 19 [abstract on PubMed] [related articles] [full text]
Selected by | Aidan Coffey
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
Controversial
Male circumcision for the prevention of acquisition and transmission of sexually transmitted infections: the case for neonatal circumcision.
Tobian AA, Gray RH, Quinn TC
Arch Pediatr Adolesc Med 2010 Jan 164(1):78-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jacqueline Upcroft
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Regulation of Cytokinesis by the Formin cdc12p.
Yonetani A, Chang F
Curr Biol 2010 Mar 10 [abstract on PubMed] [related articles] [full text]
Selected by | Mohan Balasubramanian
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch.
Bai F, Branch RW, …, Maini PK, Berry RM
Science 2010 Feb 5 327(5966):685-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laurie Betts and Matt Redinbo
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Chemotactic activation of Dictyostelium AGC-family kinases AKT and PKBR1 requires separate but coordinated functions of PDK1 and TORC2.
Liao XH, Buggey J, Kimmel AR
J Cell Sci 2010 Mar 15 123(Pt 6):983-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jeffrey Williams
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
Compounds of the upper gastrointestinal tract induce rapid and efficient excystation of Entamoeba invadens.
Mitra BN, Pradel G, Frevert U, Eichinger D
Int J Parasitol 2009 Dec 14 [abstract on PubMed] [related articles] [full text]
Selected by | Upinder Singh
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
A new nuclear function of the Entamoeba histolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity.
Tovy A, Siman Tov R, …, Helm M, Ankri S
PLoS Pathog 2010 6(2):e1000775 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Upinder Singh
Evaluated 18 Mar 2010


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