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F1000 Factor 3.0

Tech Advance
Characterization of a Novel LysM Domain from Lactobacillus fermentum Bacteriophage Endolysin and Its Use as an Anchor to Display Heterologous Proteins on the Surface of Lactic Acid Bacteria.
Hu S, Kong J, …, Guo T, Ji M
Appl Environ Microbiol 2010 Feb 19 [abstract on PubMed] [related articles] [full text]
Selected by | Aidan Coffey
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
Controversial
Male circumcision for the prevention of acquisition and transmission of sexually transmitted infections: the case for neonatal circumcision.
Tobian AA, Gray RH, Quinn TC
Arch Pediatr Adolesc Med 2010 Jan 164(1):78-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jacqueline Upcroft
Evaluated 19 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
An essential role for XBP-1 in host protection against immune activation in C. elegans.
Richardson CE, Kooistra T, Kim DH
Nature 2010 Feb 25 463(7284):1092-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Maria Markaki and Nektarios Tavernarakis
Evaluated 18 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis.
Wier AM, Nyholm SV, …, Ruby EG, McFall-Ngai MJ
Proc Natl Acad Sci U S A 2010 Feb 2 107(5):2259-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jyl Matson and Victor DiRita
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli.
Wiles TJ, Bower JM, Redd MJ, Mulvey MA
PLoS Pathog 2009 Dec 5(12):e1000697 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurent Boyer and Emmanuel Lemichez
Evaluated 17 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.
Popp C, Dean W, …, Jacobsen SE, Reik W
Nature 2010 Feb 25 463(7284):1101-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nina Papavasiliou
Evaluated 17 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Resilience to bacterial infection: difference between species could be due to proteins in serum.
Warren HS, Fitting C, …, Hayden D, Cavaillon JM
J Infect Dis 2010 Jan 15 201(2):223-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Oberdan Leo and Muriel Moser
Evaluated 17 Mar 2010


Recommended
F1000 Factor 3.0

New Finding
A novel high-affinity sucrose transporter is required for virulence of the plant pathogen Ustilago maydis.
Wahl R, Wippel K, …, Kämper J, Sauer N
PLoS Biol 2010 8(2):e1000303 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anke Reinders and John Ward
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Lack of CXC Chemokine Receptor 3 Signaling Leads to Hypertrophic and Hypercellular Scarring.
Yates CC, Krishna P, …, Turner T, Wells A
Am J Pathol 2010 Mar 4 [abstract on PubMed] [related articles] [full text]
Selected by | Giulio Gabbiani
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Rapid beta-lactam-induced lysis requires successful assembly of the cell division machinery.
Chung HS, Yao Z, …, Beckwith J, Kahne D
Proc Natl Acad Sci U S A 2009 Dec 22 106(51):21872-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Will Stubbings and Harald Labischinski
Evaluated 16 Mar 2010


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