22-Mar-2010
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Must Read
F1000 Factor
6.0
Tech Advance
A human gut microbial gene catalogue established by metagenomic sequencing.
Qin J, Li R, …, Ehrlich SD, Wang J
Nature
2010 Mar 4
464
(7285):59-65 [
abstract on PubMed
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Selected by
| Andrew Anforra and Scott Lesley
Evaluated 22 Mar 2010
Recommended
F1000 Factor
3.0
New Finding
Metabolic Autocrine Regulation of Neurons Involves Cooperation among Pannexin Hemichannels, Adenosine Receptors, and KATP Channels.
Kawamura M, Ruskin DN, Masino SA
J Neurosci
2010 Mar 17
30
(11):3886-95 [
abstract on PubMed
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Selected by
| Eric Nestler
Evaluated 22 Mar 2010
Must Read
F1000 Factor
6.0
Hypothesis
New Finding
Novel Drug Target
CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site.
Letellier E, Kumar S, …, Karray S, Martin-Villalba A
Immunity
2010 Feb 26
32
(2):240-52 [
abstract on PubMed
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Selected by
| Juan Rivera
Evaluated 22 Mar 2010
Recommended
F1000 Factor
3.0
Confirmation
New Finding
Novel Drug Target
Regulation of leukocyte recruitment by the long pentraxin PTX3.
Deban L, Russo RC, …, Bottazzi B, Mantovani A
Nat Immunol
2010 Apr
11
(4):328-34 [
abstract on PubMed
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Selected by
| Xingfeng Bao and Minoru Fukuda
Evaluated 22 Mar 2010
Must Read
F1000 Factor
6.0
New Finding
Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex.
Burgos PV, Mardones GA, …, Hurley JH, Bonifacino JS
Dev Cell
2010 Mar 16
18
(3):425-436 [
abstract on PubMed
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Selected by
| Peter Mayinger
Evaluated 22 Mar 2010
Exceptional
F1000 Factor
9.0
Hypothesis
New Finding
Kinetochores generate microtubules with distal plus ends: their roles and limited lifetime in mitosis.
Kitamura E, Tanaka K, …, Antony C, Tanaka TU
Dev Cell
2010 Feb 16
18
(2):248-59 [
abstract on PubMed
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Selected by
| Mary Dasso
Evaluated 22 Mar 2010
Recommended
F1000 Factor
3.0
New Finding
The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy.
Yen WL, Shintani T, …, Baba M, Klionsky DJ
J Cell Biol
2010 Jan 11
188
(1):101-14 [
abstract on PubMed
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Selected by
| Fulvio Reggiori and Judith Klumperman
Evaluated 22 Mar 2010
Exceptional
F1000 Factor
9.0
New Finding
A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.
Ashida H, Kim M, …, Ogawa M, Sasakawa C
Nat Cell Biol
2010 Jan
12
(1):66-73; sup pp 1-9 [
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Selected by
| Mélanie Hamon and Pascale Cossart
Evaluated 22 Mar 2010
Must Read
F1000 Factor
6.0
New Finding
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.
Lee JH, Budanov AV, …, Bier E, Karin M
Science
2010 Mar 5
327
(5970):1223-8 [
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Selected by
| Heinz Osiewacz
Evaluated 19 Mar 2010
Must Read
F1000 Factor
6.0
Confirmation
Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons.
Dubreuil V, Thoby-Brisson M, …, Fortin G, Goridis C
J Neurosci
2009 Nov 25
29
(47):14836-46 [
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Selected by
| Donald McCrimmon
Evaluated 19 Mar 2010
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