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Renal Biology
Renal Pharmacology
Renal, Fluid & Electrolyte Physiology

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Recommended
F1000 Factor 3.0

Confirmation
 Smooth muscle-specific deletion of nitric oxide-sensitive guanylyl cyclase is sufficient to induce hypertension in mice.
Groneberg D, König P, …, Koesling D, Friebe A
Circulation 2010 Jan 26 121(3):401-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Schwartz
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Testosterone increases urinary calcium excretion and inhibits expression of renal calcium transport proteins.
Hsu YJ, Dimke H, …, Hoenderop JG, Bindels RJ
Kidney Int 2010 Apr 77(7):601-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joanna Cagnard and Dominique Eladari
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
 Altered whole kidney blood flow autoregulation in a mouse model of reduced beta-ENaC.
Grifoni SC, Chiposi R, …, Ryan MJ, Drummond HA
Am J Physiol Renal Physiol 2010 Feb 298(2):F285-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Amit Patel and John Lorenz
Evaluated 15 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
 Angiotensin II Promotes Development of the Renal Microcirculation through AT1 Receptors.
Madsen K, Marcussen N, …, Coffman TM, Jensen BL
J Am Soc Nephrol 2010 Mar 21(3):448-459 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hayo Castrop
Evaluated 11 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport.
Wang J, Knight ZA, …, Shokat KM, Pearce D
Am J Physiol Renal Physiol 2008 Sep 295(3):F843-50 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carolyn Ecelbarger
Evaluated 4 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Kidney development in the absence of Gdnf and Spry1 requires Fgf10.
Michos O, Cebrian C, …, Martin GR, Costantini F
PLoS Genet 2010 Jan 6(1):e1000809 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gregory Dressler
Evaluated 4 Mar 2010


Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Inhibition of calcineurin phosphatase promotes exocytosis of renin from juxtaglomerular cells.
Madsen K, Friis UG, …, Skøtt O, Jensen BL
Kidney Int 2010 Jan 77(2):110-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonatan Barrera and Norma A Bobadilla
Evaluated 4 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Tech Advance
Novel Drug Target
 A selective EP4 PGE2 receptor agonist alleviates disease in a new mouse model of X-linked nephrogenic diabetes insipidus.
Li JH, Chou CL, …, Knepper MA, Wess J
J Clin Invest 2009 Oct 119(10):3115-26 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joanna Cagnard and Dominique Eladari
Evaluated 2 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation.
Lu Y, Ma X, …, Chapleau MW, Abboud FM
Neuron 2009 Dec 24 64(6):885-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Helle Prætorius
Evaluated 2 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Controversial
 Repeated inspiratory occlusions in anesthetized rats acutely increase blood coagulability as assessed by thromboelastography.
Othman M, Gordon SP, Iscoe S
Respir Physiol Neurobiol 2010 Jan 25 [abstract on PubMed] [related articles] [full text]
Selected by | James Duffin
Evaluated 1 Mar 2010


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