17-Mar-2010
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Recommended
F1000 Factor
3.0
Hypothesis
New Finding
eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.
Jiang Z, Belforte JE, …, Lu B, Nakazawa K
J Neurosci
2010 Feb 17
30
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Selected by
| Shari Wiseman and Angus Nairn
Evaluated 16 Mar 2010
Must Read
F1000 Factor
6.0
Hypothesis
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Lack of CXC Chemokine Receptor 3 Signaling Leads to Hypertrophic and Hypercellular Scarring.
Yates CC, Krishna P, …, Turner T, Wells A
Am J Pathol
2010 Mar 4 [
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| Giulio Gabbiani
Evaluated 16 Mar 2010
Must Read
F1000 Factor
4.8
New Finding
Plakophilin 1 stimulates translation by promoting eIF4A1 activity.
Wolf A, Krause-Gruszczynska M, …, Hüttelmaier S, Hatzfeld M
J Cell Biol
2010 Feb 22
188
(4):463-71 [
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Selected by
| Meryem Bektas and David Rubenstein
/ Robert Carnahan and Albert Reynolds
Evaluated 16 Mar 2010
Recommended
F1000 Factor
3.0
Confirmation
Hypothesis
Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.
Lichtenberger BM, Tan PK, …, Petzelbauer P, Sibilia M
Cell
2010 Jan 22
140
(2):268-79 [
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Selected by
| Arthur Mercurio
Evaluated 15 Mar 2010
Recommended
F1000 Factor
3.0
New Finding
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Greber B, Wu G, …, Tesar P, Schöler HR
Cell Stem Cell
2010 Mar 5
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(3):215-226 [
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Selected by
| Patrick Tam
Evaluated 15 Mar 2010
Must Read
F1000 Factor
6.0
Hypothesis
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J Cell Sci
2009 Nov 15
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(Pt 22):4150-9 [
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Selected by
| Stephen Lockett
Evaluated 15 Mar 2010
Recommended
F1000 Factor
3.0
New Finding
Novel Drug Target
Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.
Harmon GS, Dumlao DS, …, Dong H, Glass CK
Nat Med
2010 Mar
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(3):313-8 [
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Selected by
| William H Colledge
Evaluated 15 Mar 2010
Must Read
F1000 Factor
6.0
New Finding
Spatial control of EGF receptor activation by reversible dimerization on living cells.
Chung I, Akita R, …, Schlessinger J, Mellman I
Nature
2010 Mar 7 [
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Selected by
| Kermit Carraway
Evaluated 15 Mar 2010
Recommended
F1000 Factor
3.0
Hypothesis
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Yap is a novel regulator of C2C12 myogenesis.
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Biochem Biophys Res Commun
2010 Feb 10 [
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Selected by
| Dannel McCollum
Evaluated 15 Mar 2010
Recommended
F1000 Factor
3.0
Hypothesis
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Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX.
Szilard RK, Jacques PE, …, Robert F, Durocher D
Nat Struct Mol Biol
2010 Mar
17
(3):299-305 [
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Selected by
| Michael Lee and Michael B Yaffe
Evaluated 15 Mar 2010
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