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Browse > Cell Biology > Cell Signalling
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F1000 Factor 3.0

Hypothesis
New Finding
 eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.
Jiang Z, Belforte JE, …, Lu B, Nakazawa K
J Neurosci 2010 Feb 17 30(7):2582-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Shari Wiseman and Angus Nairn
Evaluated 16 Mar 2010

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F1000 Factor 6.0

Hypothesis
New Finding
 Lack of CXC Chemokine Receptor 3 Signaling Leads to Hypertrophic and Hypercellular Scarring.
Yates CC, Krishna P, …, Turner T, Wells A
Am J Pathol 2010 Mar 4 [abstract on PubMed] [related articles] [full text]
Selected by | Giulio Gabbiani
Evaluated 16 Mar 2010

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F1000 Factor 4.8

New Finding
 Plakophilin 1 stimulates translation by promoting eIF4A1 activity.
Wolf A, Krause-Gruszczynska M, …, Hüttelmaier S, Hatzfeld M
J Cell Biol 2010 Feb 22 188(4):463-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Meryem Bektas and David Rubenstein / Robert Carnahan and Albert Reynolds
Evaluated 16 Mar 2010

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F1000 Factor 3.0

Confirmation
Hypothesis
 Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.
Lichtenberger BM, Tan PK, …, Petzelbauer P, Sibilia M
Cell 2010 Jan 22 140(2):268-79 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arthur Mercurio
Evaluated 15 Mar 2010

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F1000 Factor 3.0

New Finding
 Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells.
Greber B, Wu G, …, Tesar P, Schöler HR
Cell Stem Cell 2010 Mar 5 6(3):215-226 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patrick Tam
Evaluated 15 Mar 2010

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F1000 Factor 6.0

Hypothesis
New Finding
 Stat3 promotes directional cell migration by regulating Rac1 activity via its activator betaPIX.
Teng TS, Lin B, …, Ng DC, Cao X
J Cell Sci 2009 Nov 15 122(Pt 22):4150-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Lockett
Evaluated 15 Mar 2010

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F1000 Factor 3.0

New Finding
Novel Drug Target
 Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.
Harmon GS, Dumlao DS, …, Dong H, Glass CK
Nat Med 2010 Mar 16(3):313-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William H Colledge
Evaluated 15 Mar 2010

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F1000 Factor 6.0

New Finding
 Spatial control of EGF receptor activation by reversible dimerization on living cells.
Chung I, Akita R, …, Schlessinger J, Mellman I
Nature 2010 Mar 7 [abstract on PubMed] [related articles] [full text]
Selected by | Kermit Carraway
Evaluated 15 Mar 2010

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F1000 Factor 3.0

Hypothesis
New Finding
 Yap is a novel regulator of C2C12 myogenesis.
Watt KI, Judson R, …, Bari CD, Wackerhage H
Biochem Biophys Res Commun 2010 Feb 10 [abstract on PubMed] [related articles] [full text]
Selected by | Dannel McCollum
Evaluated 15 Mar 2010

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F1000 Factor 3.0

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Szilard RK, Jacques PE, …, Robert F, Durocher D
Nat Struct Mol Biol 2010 Mar 17(3):299-305 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Lee and Michael B Yaffe
Evaluated 15 Mar 2010


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