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F1000 Factor 3.0

New Finding
Spontaneous assembly and active disassembly balance adherens junction homeostasis.
Hong S, Troyanovsky RB, Troyanovsky SM
Proc Natl Acad Sci U S A 2010 Feb 23 107(8):3528-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christine Chiasson and Andrew Kowalczyk
Evaluated 19 Mar 2010

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F1000 Factor 3.0

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Novel Drug Target
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Steele BM, Harper MT, …, Fitzgerald DJ, Maguire PB
Proc Natl Acad Sci U S A 2009 Nov 24 106(47):19836-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kelly A O’Brien and Xiaoping Du
Evaluated 18 Mar 2010

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F1000 Factor 3.0

Hypothesis
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JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.
Li JP, Fu YN, Chen YR, Tan TH
J Biol Chem 2010 Feb 19 285(8):5472-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony J Baucum II and Brian Wadzinski
Evaluated 17 Mar 2010

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F1000 Factor 4.8

New Finding
Plakophilin 1 stimulates translation by promoting eIF4A1 activity.
Wolf A, Krause-Gruszczynska M, …, Hüttelmaier S, Hatzfeld M
J Cell Biol 2010 Feb 22 188(4):463-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Meryem Bektas and David Rubenstein / Robert Carnahan and Albert Reynolds
Evaluated 16 Mar 2010

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F1000 Factor 6.0

Hypothesis
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Stat3 promotes directional cell migration by regulating Rac1 activity via its activator betaPIX.
Teng TS, Lin B, …, Ng DC, Cao X
J Cell Sci 2009 Nov 15 122(Pt 22):4150-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Lockett
Evaluated 15 Mar 2010

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F1000 Factor 3.0

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The interaction of angiocidin with tissue transglutaminase.
L'Heureux DZ, Rothman VL, Tuszynski GP
Exp Mol Pathol 2010 Feb 88(1):15-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alexey Belkin
Evaluated 15 Mar 2010

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F1000 Factor 3.0

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Quantitative differences in tissue surface tension influence zebrafish germ layer positioning.
Schötz EM, Burdine RD, …, Heisenberg CP, Foty RA
HFSP J 2008 Feb 2(1):42-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mariana Benítez Keinrad and Elena Alvarez-Buylla
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F1000 Factor 3.0

Confirmation
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Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice.
Cui YF, Hargus G, …, Schachner M, Bernreuther C
Brain 2010 Jan 133(Pt 1):189-204 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wei-Li Kuan and Roger Barker
Evaluated 11 Mar 2010

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F1000 Factor 3.0

Confirmation
New Finding
AnkyrinG is required to maintain axo-dendritic polarity in vivo.
Sobotzik JM, Sie JM, …, Deller T, Schultz C
Proc Natl Acad Sci U S A 2009 Oct 13 106(41):17564-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Julien Courchet and Franck Polleux
Evaluated 9 Mar 2010

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F1000 Factor 3.0

New Finding
Adherens junctions connect stress fibers between adjacent endothelial cells.
Millan J, Cain RJ, …, Correas I, Ridley AJ
BMC Biol 2010 Feb 2 8(1):11 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Christopher Stipp
Evaluated 9 Mar 2010


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