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Browse > Cell Biology > Nuclear Structure & Function
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Must Read
F1000 Factor 6.0

New Finding
 Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells.
Peng JC, Valouev A, …, Sidow A, Wysocka J
Cell 2009 Dec 24 139:1290-302 [abstract on PubMed] [related articles] [order article]
Selected by | Andreas Wodarz
Evaluated 5 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 Extrachromosomal histone H2B mediates innate antiviral immune responses induced by intracellular double-stranded DNA.
Kobiyama K, Takeshita F, …, Okuda K, Suzuki K
J Virol 2010 Jan 84(2):822-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Diana Elizabeth Koch and Nancy Sawtell
Evaluated 4 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
Tech Advance
 Protein phosphatase 1 regulates the histone code for long-term memory.
Koshibu K, Gräff J, …, Bollen M, Mansuy IM
J Neurosci 2009 Oct 14 29(41):13079-89 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laura Trinkle-Mulcahy
Evaluated 3 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin.
Miotto B, Struhl K
Mol Cell 2010 37:57-66 [full text]
Selected by | Jessica Downs
Evaluated 3 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression.
Omberg L, Meyerson JR, …, Diffley JF, Alter O
Mol Syst Biol 2009 5:312 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Marcel Mechali
Evaluated 2 Feb 2010

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
 BubR1- and Polo-Coated DNA Tethers Facilitate Poleward Segregation of Acentric Chromatids
Royou A, Gagou ME, Karess R, Sullivan W
Cell 2010 140:235-245 [full text]
Selected by | Beat Suter
Evaluated 29 Jan 2010

Recommended
F1000 Factor 3.0

New Finding
 Segregation distortion and the evolution of sex-determining mechanisms.
Kozielska M, Weissing FJ, Beukeboom LW, Pen I
Heredity 2010 Jan 104(1):100-12 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Deborah Charlesworth
Evaluated 29 Jan 2010

Recommended
F1000 Factor 3.2

New Finding
Tech Advance
Novel Drug Target
 The transcriptional network for mesenchymal transformation of brain tumours.
Carro MS, Lim WK, …, Califano A, Iavarone A
Nature 2010 Jan 21 463(7279):318-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Zhihua Li and Bino John / Andrew D Sharrocks
First evaluation 29 Jan 2010 | Latest evaluation 4 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements in the ciliate Paramecium tetraurelia.
Baudry C, Malinsky S, …, Meyer E, Bétermier M
Genes Dev 2009 Nov 1 23(21):2478-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kathy Collins
Evaluated 29 Jan 2010

Exceptional
F1000 Factor 9.6

Confirmation
Hypothesis
New Finding
 Aire's partners in the molecular control of immunological tolerance.
Abramson J, Giraud M, Benoist C, Mathis D
Cell 2010 Jan 8 140(1):123-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Shiv Pillai / Bruno Kyewski
First evaluation 28 Jan 2010 | Latest evaluation 3 Feb 2010


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