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Browse > Cell Biology > Membranes & Sorting
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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates.
Liu B, Larsson L, …, Grantham J, Nystrom T
Cell 2010 140:257-67 [full text]
Selected by | Andrei Fagarasanu, Fred Mast and Richard Rachubinski
Evaluated 8 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition.
Rasola A, Sciacovelli M, …, Brusilow WS, Bernardi P
Proc Natl Acad Sci U S A 2010 Jan 12 107(2):726-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mar González-Barroso and Eduardo Rial
Evaluated 5 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
 Differences in human macrophage receptor usage, lysosomal fusion kinetics and survival between logarithmic and metacyclic Leishmania infantum chagasi promastigotes.
Ueno N, Bratt CL, Rodriguez NE, Wilson ME
Cell Microbiol 2009 Dec 11(12):1827-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mary Ann McDowell
Evaluated 5 Feb 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects.
Acin-Perez R, Salazar E, …, Schon EA, Manfredi G
EMBO Mol Med 2009 Nov 1(8-9):392-406 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Eduardo Rial
Evaluated 5 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 Endocytosis Is Required for Efficient Apical Constriction during Xenopus Gastrulation.
Lee JY, Harland RM
Curr Biol 2010 Jan 20 [abstract on PubMed] [related articles] [full text]
Selected by | John Wallingford
Evaluated 4 Feb 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Transient assembly of F-actin by phagosomes delays phagosome fusion with lysosomes in cargo-overloaded macrophages.
Liebl D, Griffiths G
J Cell Sci 2009 Aug 15 122(Pt 16):2935-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mary Ann McDowell
Evaluated 4 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation.
Lidke DS, Huang F, …, Jovin TM, Lenormand P
J Biol Chem 2010 Jan 29 285:3092-102 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ivor Mason
Evaluated 3 Feb 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.
Kasai M, Tanida I, …, Ikeda T, Mizuochi T
J Immunol 2009 Dec 1 183(11):7278-85 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jan Lünemann and Christian Münz
Evaluated 3 Feb 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.
Wiersma H, Gatti A, …, Kuipers F, Tietge UJ
Hepatology 2009 Oct 50(4):1263-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bruno Stieger
Evaluated 3 Feb 2010

Exceptional
F1000 Factor 9.0

New Finding
 The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins.
Santarella-Mellwig R, Franke J, …, Mattaj IW, Devos DP
PLoS Biol 2010 8(1):e1000281 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Naomi Ward
Evaluated 2 Feb 2010


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