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Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Tech Advance
Loss of Aip1 reveals a role in maintaining the actin monomer pool and an in vivo oligomer assembly pathway.
Okreglak V, Drubin DG
J Cell Biol 2010 Mar 15 [abstract on PubMed] [related articles] [full text]
Selected by | Pekka Lappalainen
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Regulation of Cytokinesis by the Formin cdc12p.
Yonetani A, Chang F
Curr Biol 2010 Mar 10 [abstract on PubMed] [related articles] [full text]
Selected by | Mohan Balasubramanian
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB.
Min J, Zaslavsky A, …, Loda M, Cichowski K
Nat Med 2010 Mar 16(3):286-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ilaria Esposito and Filippo Giancotti
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase.
Liu D, Vleugel M, …, Cheeseman IM, Lampson MA
J Cell Biol 2010 Mar 15 [abstract on PubMed] [related articles] [full text]
Selected by | Vincent Vanoosthuyse and Kevin Hardwick
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase.
Beck H, Nähse V, …, Syljuåsen RG, Sørensen CS
J Cell Biol 2010 Mar 8 188(5):629-38 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Etienne Schwob
Evaluated 18 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression.
Yamaguchi T, Cubizolles F, …, Seiser C, Matthias P
Genes Dev 2010 Mar 1 24(5):455-69 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Chaya Kalcheim
Evaluated 16 Mar 2010

Must Read
F1000 Factor 4.8

New Finding
Plakophilin 1 stimulates translation by promoting eIF4A1 activity.
Wolf A, Krause-Gruszczynska M, …, Hüttelmaier S, Hatzfeld M
J Cell Biol 2010 Feb 22 188(4):463-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Meryem Bektas and David Rubenstein / Robert Carnahan and Albert Reynolds
Evaluated 16 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development.
Lichtenberger BM, Tan PK, …, Petzelbauer P, Sibilia M
Cell 2010 Jan 22 140(2):268-79 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arthur Mercurio
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
The interaction of angiocidin with tissue transglutaminase.
L'Heureux DZ, Rothman VL, Tuszynski GP
Exp Mol Pathol 2010 Feb 88(1):15-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alexey Belkin
Evaluated 15 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Spatial control of EGF receptor activation by reversible dimerization on living cells.
Chung I, Akita R, …, Schlessinger J, Mellman I
Nature 2010 Mar 7 [abstract on PubMed] [related articles] [full text]
Selected by | Kermit Carraway
Evaluated 15 Mar 2010


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