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Browse > Cell Biology > Cell Growth & Division
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Exceptional
F1000 Factor 9.0

New Finding
 PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice.
Baudat F, Buard J, …, Coop G, de Massy B
Science 2009 Dec 31 [abstract on PubMed] [related articles] [full text]
Selected by | Laurie Stevison and Mohamed Noor
Evaluated 9 Feb 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates.
Liu B, Larsson L, …, Grantham J, Nystrom T
Cell 2010 140:257-67 [full text]
Selected by | Andrei Fagarasanu, Fred Mast and Richard Rachubinski
Evaluated 8 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition.
Rasola A, Sciacovelli M, …, Brusilow WS, Bernardi P
Proc Natl Acad Sci U S A 2010 Jan 12 107(2):726-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mar González-Barroso and Eduardo Rial
Evaluated 5 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 The nuclear experience of CPEB: implications for RNA processing and translational control.
Lin CL, Evans V, …, Xing Y, Richter JD
RNA 2010 Feb 16(2):338-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roy Long
Evaluated 5 Feb 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.
Davidson L, Maccario H, …, Downes CP, Leslie NR
Oncogene 2009 Nov 16 29 [abstract on PubMed] [related articles] [full text]
Selected by | Maria Mancini and Alex Toker
Evaluated 5 Feb 2010

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Novel Drug Target
 Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.
Qu Q, Sun G, …, Evans RM, Shi Y
Nat Cell Biol 2010 Jan 12(1):31-40; sup pp 1-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Klementina Fon Tacer and David Mangelsdorf
Evaluated 5 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
 Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Janes MR, Limon JJ, …, Rommel C, Fruman DA
Nat Med 2010 Jan 13 [abstract on PubMed] [related articles] [full text]
Selected by | Jessica L Yecies and Brendan Manning
Evaluated 5 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
 Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes.
Byun JS, Wong MM, …, Ozato K, Gardner K
Proc Natl Acad Sci U S A 2009 Nov 17 106(46):19286-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniel Reines
Evaluated 3 Feb 2010

Must Read
F1000 Factor 6.0

New Finding
 The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer.
Murchison EP, Tovar C, …, Hannon GJ, Papenfuss AT
Science 2010 Jan 1 327(5961):84-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Landay
Evaluated 3 Feb 2010

Recommended
F1000 Factor 3.0

New Finding
 Emi2 Inhibition of the APC/C Absolutely Requires Emi2 Binding via the C-terminal RL Tail.
Ohe M, Kawamura Y, …, Nakajo N, Sagata N
Mol Biol Cell 2010 Jan 20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Jackson
Evaluated 2 Feb 2010


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