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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Somatic sex identity is cell autonomous in the chicken.
Zhao D, McBride D, …, Sang HM, Clinton M
Nature 2010 Mar 11 464(7286):237-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Craig Smith and Andrew Sinclair
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
 Smooth muscle-specific deletion of nitric oxide-sensitive guanylyl cyclase is sufficient to induce hypertension in mice.
Groneberg D, König P, …, Koesling D, Friebe A
Circulation 2010 Jan 26 121(3):401-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Schwartz
Evaluated 19 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 An essential role for XBP-1 in host protection against immune activation in C. elegans.
Richardson CE, Kooistra T, Kim DH
Nature 2010 Feb 25 463(7284):1092-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Maria Markaki and Nektarios Tavernarakis
Evaluated 18 Mar 2010

Must Read
F1000 Factor 6.0

Tech Advance
Refutation
 Preferential ethanol consumption in Drosophila models features of addiction.
Devineni AV, Heberlein U
Curr Biol 2009 Dec 29 19(24):2126-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rainer Spanagel
Evaluated 18 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
 Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance.
Tischfield MA, Baris HN, …, Pellman D, Engle EC
Cell 2010 Jan 8 140(1):74-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stuart Feinstein
Evaluated 17 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli.
Wiles TJ, Bower JM, Redd MJ, Mulvey MA
PLoS Pathog 2009 Dec 5(12):e1000697 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Laurent Boyer and Emmanuel Lemichez
Evaluated 17 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Tech Advance
 Genetic dissection of the function of hindbrain axonal commissures.
Renier N, Schonewille M, …, De Zeeuw CI, Chedotal A
Plos Biol 2010 8:e1000325 [FREE full text]
Selected by | Gilles Fortin
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Lack of CXC Chemokine Receptor 3 Signaling Leads to Hypertrophic and Hypercellular Scarring.
Yates CC, Krishna P, …, Turner T, Wells A
Am J Pathol 2010 Mar 4 [abstract on PubMed] [related articles] [full text]
Selected by | Giulio Gabbiani
Evaluated 16 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Drosophila timeless2 is required for chromosome stability and circadian photoreception.
Benna C, Bonaccorsi S, …, Costa R, Sandrelli F
Curr Biol 2010 Feb 23 20(4):346-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Reppert
Evaluated 16 Mar 2010

Must Read
F1000 Factor 4.8

New Finding
Novel Drug Target
 Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.
Harmon GS, Dumlao DS, …, Dong H, Glass CK
Nat Med 2010 Mar 16(3):313-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | William H Colledge / Hugo De Jonge
First evaluation 15 Mar 2010 | Latest evaluation 18 Mar 2010


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