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Must Read
F1000 Factor 6.4

Confirmation
Hypothesis
New Finding
Novel Drug Target
 FcRgamma activation regulates inflammation-associated squamous carcinogenesis.
Andreu P, Johansson M, …, De Palma M, Coussens LM
Cancer Cell 2010 Feb 17 17(2):121-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Xiaojing Ma / Friedemann Kiefer
Evaluated 11 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.
Traherne JA, Martin M, …, Carrington M, Trowsdale J
Hum Mol Genet 2010 Mar 1 19(5):737-51 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lutz Walter
Evaluated 9 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance.
Fu G, Chen Y, …, Wang D, Wen R
J Exp Med 2010 Feb 15 207(2):309-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Amnon Altman
Evaluated 9 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Computational identification of gene-social environment interaction at the human IL6 locus.
Cole SW, Arevalo JM, …, Sheridan JF, Seeman TE
Proc Natl Acad Sci U S A 2010 Feb 22 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Victor Reus
Evaluated 3 Mar 2010

Must Read
F1000 Factor 6.4

New Finding
 In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells.
Lee HK, Mattei LM, …, Grinstein S, Iwasaki A
Immunity 2010 Feb 26 32(2):227-239 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kiyoshi Takeda / John Kyriakis
First evaluation 3 Mar 2010 | Latest evaluation 10 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.
International Schizophrenia Consortium, Purcell SM, …, Sullivan PF, Sklar P
Nature 2009 Aug 6 460:748-52 [abstract on PubMed] [related articles] [order article]
Selected by | Robert Sapolsky
Evaluated 1 Mar 2010


Recommended
F1000 Factor 3.0

New Finding
 Common variants on chromosome 6p22.1 are associated with schizophrenia.
Shi J, Levinson DF, …, Freedman R, Gejman PV
Nature 2009 Aug 6 460(7256):753-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Sapolsky
Evaluated 1 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Common variants conferring risk of schizophrenia.
Stefansson H, Ophoff RA, …, Stefansson K, Collier DA
Nature 2009 Aug 6 460(7256):744-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Sapolsky
Evaluated 1 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Regulation of the p53 transcriptional response by structurally diverse core promoters.
Morachis JM, Murawsky CM, Emerson BM
Genes Dev 2010 Jan 15 24(2):135-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dinah Singer
Evaluated 19 Feb 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease.
McCarroll SA, Bradner JE, …, Palotie A, Altshuler D
Nat Genet 2009 Dec 41(12):1341-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ulf Pettersson
Evaluated 19 Feb 2010


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