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Must Read
F1000 Factor 6.0

New Finding
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux.
Wang Q, Zhang Y, …, Zhao S, Zhao GP
Science 2010 Feb 19 327(5968):1004-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Adrian Mehlitz and Roy Gross
Evaluated 19 Mar 2010

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Tech Advance
Loss of Aip1 reveals a role in maintaining the actin monomer pool and an in vivo oligomer assembly pathway.
Okreglak V, Drubin DG
J Cell Biol 2010 Mar 15 [abstract on PubMed] [related articles] [full text]
Selected by | Pekka Lappalainen
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Regulation of Cytokinesis by the Formin cdc12p.
Yonetani A, Chang F
Curr Biol 2010 Mar 10 [abstract on PubMed] [related articles] [full text]
Selected by | Mohan Balasubramanian
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase.
Liu D, Vleugel M, …, Cheeseman IM, Lampson MA
J Cell Biol 2010 Mar 15 [abstract on PubMed] [related articles] [full text]
Selected by | Vincent Vanoosthuyse and Kevin Hardwick
Evaluated 18 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis.
Wier AM, Nyholm SV, …, Ruby EG, McFall-Ngai MJ
Proc Natl Acad Sci U S A 2010 Feb 2 107(5):2259-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jyl Matson and Victor DiRita
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
Manganese import is a key element of the OxyR response to hydrogen peroxide in Escherichia coli.
Anjem A, Varghese S, Imlay JA
Mol Microbiol 2009 May 72(4):844-58 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Chris Kristich and John Kirby
Evaluated 17 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
A multi-step pathway for the establishment of sister chromatid cohesion.
Milutinovich M, Unal E, …, Skibbens RV, Koshland D
PLoS Genet 2007 Jan 19 3(1):e12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Dawson
Evaluated 12 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
Epigenetic inheritance of an inducibly nucleosome-depleted promoter and its associated transcriptional state in the apparent absence of transcriptional activators.
Ohsawa R, Adkins M, Tyler JK
Epigenetics Chromatin 2009 2(1):11 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Fyodor Urnov
Evaluated 12 Mar 2010

Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin.
Kawashima SA, Yamagishi Y, …, Ishiguro K, Watanabe Y
Science 2010 Jan 8 327(5962):172-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gerben Vader and Rene Medema
Evaluated 11 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway.
Krantz M, Ahmadpour D, …, Hohmann S, Kitano H
Mol Syst Biol 2009 5:281 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stanley Brul
Evaluated 11 Mar 2010


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