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Recommended
F1000 Factor 3.0

New Finding
 Regulation of Cytokinesis by the Formin cdc12p.
Yonetani A, Chang F
Curr Biol 2010 Mar 10 [abstract on PubMed] [related articles] [full text]
Selected by | Mohan Balasubramanian
Evaluated 19 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes.
Figueiredo LM, Cross GA
Eukaryot Cell 2010 Jan 9(1):148-54 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Myler
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes.
Stanne TM, Rudenko G
Eukaryot Cell 2010 Jan 9(1):136-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Myler
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Network analyses structure genetic diversity in independent genetic worlds.
Halary S, Leigh JW, …, Lopez P, Bapteste E
Proc Natl Acad Sci U S A 2010 Jan 5 107(1):127-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Camilla Nesbo
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX.
Szilard RK, Jacques PE, …, Robert F, Durocher D
Nat Struct Mol Biol 2010 Mar 17(3):299-305 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Lee and Michael B Yaffe
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
 Epigenetic inheritance of an inducibly nucleosome-depleted promoter and its associated transcriptional state in the apparent absence of transcriptional activators.
Ohsawa R, Adkins M, Tyler JK
Epigenetics Chromatin 2009 2(1):11 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Fyodor Urnov
Evaluated 12 Mar 2010

Exceptional
F1000 Factor 9.0

Confirmation
New Finding
 Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin.
Kawashima SA, Yamagishi Y, …, Ishiguro K, Watanabe Y
Science 2010 Jan 8 327(5962):172-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gerben Vader and Rene Medema
Evaluated 11 Mar 2010

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F1000 Factor 3.0

New Finding
 RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex.
Hale CR, Zhao P, …, Terns RM, Terns MP
Cell 2009 Nov 25 139(5):945-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Melinda Capes and Shiladitya DasSarma
Evaluated 10 Mar 2010

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F1000 Factor 3.0

New Finding
 On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos.
Krief S, Escalante AA, …, Rénia L, Snounou G
PLoS Pathog 2010 6(2):e1000765 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Constance Finney and Kevin Kain
Evaluated 10 Mar 2010

Recommended
F1000 Factor 3.0

Tech Advance
 Engineering of Bacillus lipase by directed evolution for enhanced thermal stability: effect of isoleucine to threonine mutation at protein surface.
Khurana J, Singh R, Kaur J
Mol Biol Rep 2010 Feb 3 [abstract on PubMed] [related articles] [full text]
Selected by | Alexander Krichevsky and Vitaly Citovsky
Evaluated 10 Mar 2010


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