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F1000 Factor 3.0

New Finding
Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration.
Garza-Garcia A, Harris R, …, Gates PB, Driscoll PC
PLoS One 2009 4(9):e7123 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Malcolm Maden
Evaluated 28 Sep 2009

Must Read
F1000 Factor 6.0

Tech Advance
Protein-protein docking with backbone flexibility.
Wang C, Bradley P, Baker D
J Mol Biol 2007 Oct 19 373(2):503-19 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stewart Moughon and Ram Samudrala
Evaluated 24 Sep 2009

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F1000 Factor 3.2

New Finding
Tech Advance
In vitro mutasynthesis of lantibiotic analogues containing nonproteinogenic amino acids.
Levengood MR, Knerr PJ, Oman TJ, van der Donk WA
J Am Chem Soc 2009 Sep 2 131(34):12024-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jan Grunewald / Des Field and Paul Cotter
First evaluation 24 Sep 2009 | Latest evaluation 26 Oct 2009

Must Read
F1000 Factor 6.0

Tech Advance
Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics.
Picotti P, Bodenmiller B, …, Domon B, Aebersold R
Cell 2009 Aug 21 138(4):795-806 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paolo Rossi
Evaluated 18 Sep 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
Merithew E, Hatherly S, …, Heller-Harrison R, Lambright DG
J Biol Chem 2001 Apr 27 276(17):13982-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ruth Collins
Evaluated 17 Sep 2009

Recommended
F1000 Factor 3.2

Hypothesis
Tech Advance
Protein occupancy landscape of a bacterial genome.
Vora T, Hottes AK, Tavazoie S
Mol Cell 2009 Jul 31 35(2):247-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Hu / Charles J. Dorman
First evaluation 17 Sep 2009 | Latest evaluation 23 Sep 2009

Must Read
F1000 Factor 6.0

New Finding
Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
Tubbs JL, Latypov V, …, Pegg AE, Tainer JA
Nature 2009 Jun 11 459(7248):808-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Aramini
Evaluated 9 Sep 2009

Must Read
F1000 Factor 6.0

New Finding
A Vertebrate Polycomb Response Element Governs Segmentation of the Posterior Hindbrain.
Sing A, Pannell D, …, Lipshitz HD, Cordes SP
Cell 2009 138:885-897 [full text]
Selected by | Filippo Rijli
Evaluated 7 Sep 2009

Must Read
F1000 Factor 6.0

New Finding
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair.
Cordeddu V, Di Schiavi E, …, Gelb BD, Tartaglia M
Nat Genet 2009 Sep 41(9):1022-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Melissa M McKay and Deborah Morrison
Evaluated 4 Sep 2009

Must Read
F1000 Factor 6.0

Tech Advance
Correlation of RNA secondary structure statistics with thermodynamic stability and applications to folding.
Wu JC, Gardner DP, …, Gutell RR, Ren P
J Mol Biol 2009 Aug 28 391(4):769-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marcelo Marucho and Nathan Baker
Evaluated 3 Sep 2009


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