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F1000 Factor 3.0

Hypothesis
Tech Advance
Characterizing hydrophobicity of interfaces by using cavity formation, solute binding, and water correlations.
Godawat R, Jamadagni SN, Garde S
Proc Natl Acad Sci U S A 2009 Sep 8 106(36):15119-24 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Qiang Cui
Evaluated 19 Mar 2010

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F1000 Factor 3.0

Hypothesis
Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch.
Bai F, Branch RW, …, Maini PK, Berry RM
Science 2010 Feb 5 327(5966):685-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laurie Betts and Matt Redinbo
Evaluated 19 Mar 2010

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F1000 Factor 6.0

Hypothesis
Tech Advance
CASD-NMR: critical assessment of automated structure determination by NMR.
Rosato A, Bagaria A, …, Vuister GW, Bonvin AM
Nat Methods 2009 Sep 6(9):625-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gottfried Otting
Evaluated 11 Mar 2010

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F1000 Factor 3.0

Hypothesis
New Finding
Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints.
Hornak V, Ahuja S, …, Reeves PJ, Smith SO
J Mol Biol 2010 Feb 26 396(3):510-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Bowie
Evaluated 10 Mar 2010

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F1000 Factor 6.0

Hypothesis
New Finding
Tech Advance
The transition state for folding of an outer membrane protein.
Huysmans GH, Baldwin SA, Brockwell DJ, Radford SE
Proc Natl Acad Sci U S A 2010 Mar 2 107(9):4099-104 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Bowie
Evaluated 10 Mar 2010

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F1000 Factor 3.0

Tech Advance
Learning rates and states from biophysical time series: a Bayesian approach to model selection and single-molecule FRET data.
Bronson JE, Fei J, …, Gonzalez RL, Wiggins CH
Biophys J 2009 Dec 16 97:3196-205 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stuart S Licht
Evaluated 8 Mar 2010

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F1000 Factor 3.0

Tech Advance
Fast screening of protein surfaces using geometric invariant fingerprints.
Yin S, Proctor EA, Lugovskoy AA, Dokholyan NV
Proc Natl Acad Sci U S A 2009 Sep 29 106(39):16622-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andras Fiser
Evaluated 5 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
The continuity of protein structure space is an intrinsic property of proteins.
Skolnick J, Arakaki AK, Lee SY, Brylinski M
Proc Natl Acad Sci U S A 2009 Sep 15 106(37):15690-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nick Grishin
Evaluated 3 Mar 2010

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F1000 Factor 3.2

Tech Advance
NMR structure determination for larger proteins using backbone-only data.
Raman S, Lange OF, …, Montelione GT, Baker D
Science 2010 Feb 19 327(5968):1014-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gira Bhabha and H Jane Dyson / Antonio Rosato
Evaluated 3 Mar 2010

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F1000 Factor 3.0

Hypothesis
Tech Advance
Organism-Scale Modeling of Early Drosophila Patterning via Bone Morphogenetic Proteins.
Umulis DM, Shimmi O, O'Connor MB, Othmer HG
Dev Cell 2010 Feb 16 18(2):260-274 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Siegfried Roth
Evaluated 2 Mar 2010


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