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Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.
Cong Y, Baker ML, …, Frydman J, Chiu W
Proc Natl Acad Sci U S A 2010 Mar 1 [abstract on PubMed] [related articles] [full text]
Selected by | Linda Amos
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
 Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch.
Bai F, Branch RW, …, Maini PK, Berry RM
Science 2010 Feb 5 327(5966):685-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Laurie Betts and Matt Redinbo
Evaluated 19 Mar 2010

Recommended
F1000 Factor 3.0

Tech Advance
 Photoreversible DNA end capping for the formation of hairpin structures.
Yoshimura Y, Okada H, Fujimoto K
Org Biomol Chem 2010 8:1523-26 [full text]
Selected by | Scott K Silverman
Evaluated 18 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24.
Martin-Tumasz S, Reiter NJ, Brow DA, Butcher SE
RNA 2010 Feb 24 [abstract on PubMed] [related articles] [full text]
Selected by | Kathleen Hall
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
New Finding
 RNA polymerase II and TAFs undergo a slow isomerization after the polymerase is recruited to promoter-bound TFIID.
Yakovchuk P, Gilman B, Goodrich JA, Kugel JF
J Mol Biol 2010 Mar 19 397(1):57-68 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tony Weil
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes.
Figueiredo LM, Cross GA
Eukaryot Cell 2010 Jan 9(1):148-54 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Myler
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes.
Stanne TM, Rudenko G
Eukaryot Cell 2010 Jan 9(1):136-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Myler
Evaluated 16 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
Tech Advance
 Pathway of ATP utilization and duplex rRNA unwinding by the DEAD-box helicase, DbpA.
Henn A, Cao W, …, Hackney DD, De La Cruz EM
Proc Natl Acad Sci U S A 2010 Mar 2 107(9):4046-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kathleen Hall
Evaluated 15 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
 The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.
Kim S, Wairkar YP, Daniels RW, Diantonio A
J Cell Biol 2010 Mar 8 188(5):717-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anne Spang
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 The interaction of angiocidin with tissue transglutaminase.
L'Heureux DZ, Rothman VL, Tuszynski GP
Exp Mol Pathol 2010 Feb 88(1):15-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alexey Belkin
Evaluated 15 Mar 2010


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