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F1000 Factor 3.0

New Finding
Testosterone increases urinary calcium excretion and inhibits expression of renal calcium transport proteins.
Hsu YJ, Dimke H, …, Hoenderop JG, Bindels RJ
Kidney Int 2010 Apr 77(7):601-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joanna Cagnard and Dominique Eladari
Evaluated 19 Mar 2010

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F1000 Factor 6.0

New Finding
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase.
Kang T, Lindsey-Boltz LA, Reardon JT, Sancar A
Pro Nat Acad Sci 2010 107:4890-5 [full text]
Selected by | Jennifer Lee and Pengbo Zhou
Evaluated 18 Mar 2010

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F1000 Factor 3.0

New Finding
Novel Drug Target
Association of increased Visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity.
Catalán V, Gómez-Ambrosi J, …, Salvador J, Frühbeck G
Nutr Metab Cardiovasc Dis 2010 Jan 25 [abstract on PubMed] [related articles] [full text]
Selected by | David Alpers
Evaluated 17 Mar 2010

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F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression.
Mennella JA, Pepino MY, Lehmann-Castor SM, Yourshaw LM
Addiction 2010 Feb 9 [abstract on PubMed] [related articles] [full text]
Selected by | Kent Berridge
Evaluated 17 Mar 2010

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F1000 Factor 3.0

Confirmation
New Finding
Controversial
FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts.
Robinson LJ, Tourkova I, …, Zaidi M, Blair HC
Biochem Biophys Res Commun 2010 Feb 19 [abstract on PubMed] [related articles] [full text]
Selected by | Steven R King and Holly LaVoie
Evaluated 17 Mar 2010

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F1000 Factor 3.0

Hypothesis
New Finding
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle.
Cantó C, Jiang LQ, …, Zierath JR, Auwerx J
Cell Metab 2010 Mar 3 11(3):213-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Means
Evaluated 17 Mar 2010

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F1000 Factor 6.0

Hypothesis
New Finding
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.
Popp C, Dean W, …, Jacobsen SE, Reik W
Nature 2010 Feb 25 463(7284):1101-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nina Papavasiliou
Evaluated 17 Mar 2010

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F1000 Factor 3.0

Hypothesis
New Finding
PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.
Banno R, Zimmer D, …, Yang W, Bence KK
J Clin Invest 2010 Mar 1 120(3):720-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Eric Gustafson
Evaluated 16 Mar 2010

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F1000 Factor 3.0

New Finding
Drosophila timeless2 is required for chromosome stability and circadian photoreception.
Benna C, Bonaccorsi S, …, Costa R, Sandrelli F
Curr Biol 2010 Feb 23 20(4):346-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Reppert
Evaluated 16 Mar 2010

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F1000 Factor 3.0

New Finding
Enduring consequences of maternal obesity for brain inflammation and behavior of offspring.
Bilbo SD, Tsang V
FASEB J 2010 Feb 2 [abstract on PubMed] [related articles] [full text]
Selected by | Deena M Walker and Andrea Gore
Evaluated 16 Mar 2010


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