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F1000 Factor 3.0

New Finding
 Metabolic Autocrine Regulation of Neurons Involves Cooperation among Pannexin Hemichannels, Adenosine Receptors, and KATP Channels.
Kawamura M, Ruskin DN, Masino SA
J Neurosci 2010 Mar 17 30(11):3886-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Eric Nestler
Evaluated 22 Mar 2010

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F1000 Factor 3.0

New Finding
 Testosterone increases urinary calcium excretion and inhibits expression of renal calcium transport proteins.
Hsu YJ, Dimke H, …, Hoenderop JG, Bindels RJ
Kidney Int 2010 Apr 77(7):601-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joanna Cagnard and Dominique Eladari
Evaluated 19 Mar 2010

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F1000 Factor 3.0

Confirmation
New Finding
Controversial
 FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts.
Robinson LJ, Tourkova I, …, Zaidi M, Blair HC
Biochem Biophys Res Commun 2010 Feb 19 [abstract on PubMed] [related articles] [full text]
Selected by | Steven R King and Holly LaVoie
Evaluated 17 Mar 2010

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F1000 Factor 3.0

New Finding
 SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Hirschey MD, Shimazu T, …, Kahn CR, Verdin E
Nature 2010 Mar 4 464(7285):121-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anthony Means
Evaluated 17 Mar 2010

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F1000 Factor 3.0

Hypothesis
New Finding
 PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.
Banno R, Zimmer D, …, Yang W, Bence KK
J Clin Invest 2010 Mar 1 120(3):720-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Eric Gustafson
Evaluated 16 Mar 2010

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F1000 Factor 3.0

New Finding
 Enduring consequences of maternal obesity for brain inflammation and behavior of offspring.
Bilbo SD, Tsang V
FASEB J 2010 Feb 2 [abstract on PubMed] [related articles] [full text]
Selected by | Deena M Walker and Andrea Gore
Evaluated 16 Mar 2010

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F1000 Factor 3.0

Confirmation
New Finding
 Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells.
Kim JY, Han EH, …, Lee KY, Jeong HG
Toxicol Lett 2010 Mar 15 193(2):200-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin van den Berg
Evaluated 15 Mar 2010

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F1000 Factor 6.0

New Finding
 Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.
Wakabayashi Y, Nakada T, …, Steiner RA, Okamura H
J Neurosci 2010 Feb 24 30(8):3124-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tony Plant
Evaluated 12 Mar 2010

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F1000 Factor 6.0

New Finding
 FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice.
Rached MT, Kode A, …, Karsenty G, Kousteni S
J Clin Invest 2010 Jan 120(1):357-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joshua J Park and Y Peng Loh
Evaluated 11 Mar 2010

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F1000 Factor 3.0

New Finding
 Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis.
Garin I, Edghill EL, …, Perez de Nanclares G, Hattersley AT
Proc Natl Acad Sci U S A 2010 Feb 16 107(7):3105-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dorothy Kakoola and Ivan Gerling
Evaluated 10 Mar 2010


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