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Browse > Pharmacology & Drug Discovery > Toxicology
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Must Read
F1000 Factor 6.0

New Finding
 Bisphenol A and estradiol are equipotent in antagonizing cisplatin-induced cytotoxicity in breast cancer cells.
Lapensee EW, Lapensee CR, …, Afton S, Ben-Jonathan N
Cancer Lett 2010 Apr 28 290(2):167-173 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin van den Berg
Evaluated 16 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells.
Kim JY, Han EH, …, Lee KY, Jeong HG
Toxicol Lett 2010 Mar 15 193(2):200-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin van den Berg
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
 Use of spermatozoal mRNA profiles to study gene-environment interactions in human germ cells.
Linschooten JO, Van Schooten FJ, …, Anderson D, Godschalk RW
Mutat Res 2009 Jul 10 667(1-2):70-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bhaskar Gollapudi
Evaluated 9 Mar 2010

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
 Lipophilicity in drug discovery.
Waring MJ
Expert Opin Drug Discov 2010 5:235-48 [full text]
Selected by | Peter Grootenhuis
Evaluated 9 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
Tech Advance
 Effects of ultrafine TiO2 particles on gene expression profile in human keratinocytes without illumination: involvement of extracellular matrix and cell adhesion.
Fujita K, Horie M, …, Iwahashi H, Nakanishi J
Toxicol Lett 2009 Dec 15 191(2-3):109-17 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Burcham
Evaluated 8 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
 Combinatorial control of suicide gene expression by tissue-specific promoter and microRNA regulation for cancer therapy.
Wu C, Lin J, …, Zeng J, Wang S
Mol Ther 2009 Dec 17(12):2058-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Gantier and Bryan Williams
Evaluated 5 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Maternal bisphenol a exposure promotes the development of experimental asthma in mouse pups.
Midoro-Horiuti T, Tiwari R, Watson CS, Goldblum RM
Environ Health Perspect 2010 Feb 118(2):273-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Joan Ruderman
Evaluated 4 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir.
Beck-Engeser GB, Eilat D, …, Jäck HM, Wabl M
Proc Natl Acad Sci U S A 2009 Nov 18 106 [abstract on PubMed] [related articles] [full text]
Selected by | Kevin Sweder
Evaluated 3 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker.
Wu MN, Joiner WJ, …, Sehgal A, Koh K
Nat Neurosci 2010 Jan 13(1):69-75 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jan Melom and J Troy Littleton
Evaluated 2 Feb 2010

Recommended
F1000 Factor 3.0

Confirmation
 An adenosine nucleoside inhibitor of dengue virus.
Yin Z, Chen YL, …, Keller TH, Shi PY
Proc Natl Acad Sci U S A 2009 Dec 1 106(48):20435-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kai Dallmeier and Johan Neyts
Evaluated 28 Jan 2010


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