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Must Read
F1000 Factor 6.0

New Finding
 Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.
Niakan KK, Ji H, …, McMahon AP, Eggan K
Genes Dev 2010 Feb 1 24(3):312-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mathias Francois and Peter Koopman
Evaluated 18 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.
Popp C, Dean W, …, Jacobsen SE, Reik W
Nature 2010 Feb 25 463(7284):1101-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nina Papavasiliou
Evaluated 17 Mar 2010

Must Read
F1000 Factor 6.0

New Finding
 Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.
Snippert HJ, Haegebarth A, …, Toftgård R, Clevers H
Science 2010 Mar 12 327(5971):1385-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yukiko Yamashita
Evaluated 17 Mar 2010

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle.
Uezumi A, Fukada S, …, Takeda S, Tsuchida K
Nat Cell Biol 2010 Feb 12(2):143-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Denis Guttridge
Evaluated 16 Mar 2010


Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.
Matsui T, Leung D, …, Lorincz MC, Shinkai Y
Nature 2010 Feb 17 [abstract on PubMed] [related articles] [full text]
Selected by | Andrea Schorn and Robert Martienssen
Evaluated 16 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells.
Greber B, Wu G, …, Tesar P, Schöler HR
Cell Stem Cell 2010 Mar 5 6(3):215-226 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patrick Tam
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Yap is a novel regulator of C2C12 myogenesis.
Watt KI, Judson R, …, Bari CD, Wackerhage H
Biochem Biophys Res Commun 2010 Feb 10 [abstract on PubMed] [related articles] [full text]
Selected by | Dannel McCollum
Evaluated 15 Mar 2010

Exceptional
F1000 Factor 9.0

New Finding
 Reprogramming towards pluripotency requires AID-dependent DNA demethylation.
Bhutani N, Brady JJ, …, Corbel SY, Blau HM
Nature 2010 Feb 25 463(7284):1042-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Naga Rama Kothapalli and Sebastian Fugmann
Evaluated 15 Mar 2010

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice.
Cui YF, Hargus G, …, Schachner M, Bernreuther C
Brain 2010 Jan 133(Pt 1):189-204 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wei-Li Kuan and Roger Barker
Evaluated 11 Mar 2010

Recommended
F1000 Factor 3.0

New Finding
 Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration.
Shea KL, Xiang W, …, Basson MA, Brack AS
Cell Stem Cell 2010 Feb 5 6(2):117-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Keren Bismuth and David Sassoon
Evaluated 11 Mar 2010


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