Welcome to F1000 Biology - the expert guide to the most important advances in biology

Recommended
F1000 Factor 3.2

Hypothesis
A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action.
Makarova KS, Grishin NV, ..., Wolf YI, Koonin EV
Biol Direct 2006 1:7- [abstract on PubMed] [related articles] [FREE full text] [order article]
Selected by | Richard Willson / Julian Parkhill
First evaluation 04 Jul 06 | Latest evaluation 01 Aug 06

"All archaeal and many bacterial genomes contain Clustered Regularly Interspaced Short..."

To read the rest of this authoritative evaluation by Richard Willson (University of Houston) simply sign-up for a free 3-week trial or take advantage of our special reduced-rate subscription

  • Individuals

    Login or Register to get your 3-week trial for instant access to evaluations from over 2000 of the world's top scientists.

    Get a free 3-free trial Want to continue searching for interesting papers?
    Browse F1000 Biology

  • Recommendations

    Send a recommendation to your institution's librarian or information manager to request an extended free trial for all users.

    Send a recommendation

  • Librarians & information managers

    Get an extended free trial supporting clinicians and researchers at your academic or corporate institution.

    Request a trial