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F1000 Factor 6.7

Hypothesis
New Finding
An mRNA m7G cap binding-like motif within human Ago2 represses translation.
Kiriakidou M, Tan GS, ..., Nelson PT, Mourelatos Z
Cell 2007 Jun 15 129 (6):1141-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bino John / Michael Kiebler / Michael Cole / Nektarios Tavernarakis
First evaluation 30 May 07 | Latest evaluation 28 Aug 07

"The results suggest a molecular mechanism for microRNA-mediated regulation of mRNAs,..."

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