Faculty of 1000 Biology | Current Top 10

18-Mar-2010

Top 10s

Genomics & Genetics

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Animal Genetics

Bioinformatics

Evolutionary/Comparative Genetics

Genomics

Medical Genetics

Related Sections

Cell Growth & Division

Control of Gene Expression

Genetics of the Immune System

Microbial Evolution & Genomics

Nuclear Structure & Function

Pharmacogenomics

Physiogenomics

Plant Genetics & Gene Expression

Plant Genomes & Evolution

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	Exceptional
F1000 Factor 9.6

Hypothesis

New Finding

Abundance of ribosomal RNA gene copies maintains genome integrity.
Ide S, Miyazaki T, Maki H, Kobayashi T
Science 2010 Feb 5 327(5966):693-6 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Joachim Messing / Anna Chambers and Jessica Downs
Evaluated 18 Feb 2010

	Exceptional
F1000 Factor 8.0

Confirmation

Hypothesis

New Finding

Tech Advance

Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells.
Schoenfelder S, Sexton T, …, Bieker JJ, Fraser P
Nat Genet 2010 Jan 42(1):53-61 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Dean Jackson / Vicky Zhou, Alon Goren and Brad Bernstein
First evaluation 14 Jan 2010 | Latest evaluation 4 Mar 2010

	Exceptional
F1000 Factor 8.0

New Finding

Tech Advance

A role for the elongator complex in zygotic paternal genome demethylation.
Okada Y, Yamagata K, …, Wakayama T, Zhang Y
Nature 2010 Jan 28 463(7280):554-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kevin Huang and Guoping Fan / Pamela Geyer
First evaluation 19 Feb 2010 | Latest evaluation 25 Feb 2010

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm.
Kalverda B, Pickersgill H, Shloma VV, Fornerod M
Cell 2010 Feb 5 140(3):360-71 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Pamela Geyer / Lucio Comai
First evaluation 16 Feb 2010 | Latest evaluation 22 Feb 2010

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes.
Capelson M, Liang Y, …, Wagner U, Hetzer MW
Cell 2010 Feb 5 140(3):372-83 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Pamela Geyer / Lucio Comai
First evaluation 17 Feb 2010 | Latest evaluation 22 Feb 2010

	Must Read
F1000 Factor 6.7

Confirmation

New Finding

Tech Advance

The genetic landscape of a cell.
Costanzo M, Baryshnikova A, …, Andrews BJ, Boone C
Science 2010 Jan 22 327(5964):425-31 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Eulalia de Nadal and Francesc Posas / Jurg Bahler / Nicholas P Tatonetti and Russ Altman / Jamie Snider and Igor Stagljar
First evaluation 2 Feb 2010 | Latest evaluation 16 Feb 2010

	Must Read
F1000 Factor 6.5

Hypothesis

New Finding

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells.
Melton C, Judson RL, Blelloch R
Nature 2010 Feb 4 463(7281):621-6 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Wenqian Hu and Jeff Coller / Amar Singh and Stephen Dalton / Martine Roussel
First evaluation 9 Feb 2010 | Latest evaluation 4 Mar 2010

	Must Read
F1000 Factor 6.4

Confirmation

Hypothesis

New Finding

Tech Advance

Whole-Genome Sequencing in a Patient with Charcot-Marie-Tooth Neuropathy.
Lupski JR, Reid JG, …, Muzny DM, Gibbs RA
N Engl J Med 2010 Mar 10 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Sue Malcolm

/ Anthony Antonellis

Evaluated 15 Mar 2010

	Must Read
F1000 Factor 6.4

New Finding

Control of iron homeostasis by an iron-regulated ubiquitin ligase.
Vashisht AA, Zumbrennen KB, …, Leibold EA, Wohlschlegel JA
Science 2009 Oct 30 326(5953):718-21 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Caroline Philpott / Antonio Sarikas and Zhen-Qiang Pan

First evaluation 2 Feb 2010 | Latest evaluation 15 Mar 2010

	Recommended
F1000 Factor 3.2

Confirmation

Tech Advance

Controversial

A galaxy of folds.
Alva V, Remmert M, …, Lupas AN, Söding J
Protein Sci 2010 Jan 19(1):124-30 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Yuri Wolf / Yuanpeng Janet Huang
First evaluation 17 Feb 2010 | Latest evaluation 10 Mar 2010

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.