Faculty of 1000 Biology | Current Top 10

16-Mar-2010

Top 10s

Structural Biology

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Biomacromolecule-Ligand Interactions

Cell Signalling & Trafficking Structures

Experimental Biophysical Methods

Macromolecular Assemblies & Machines

Membrane Proteins & Energy Transduction

Protein Folding

Structural Genomics

Structure: RNA

Structure: Replication & Repair

Structure: Transcription & Translation

Theory & Simulation

Related Sections

Biocatalysis

Protein Chemistry & Proteomics

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	Exceptional
F1000 Factor 8.0

New Finding

Tech Advance

Active site remodelling accompanies thioester bond formation in the SUMO E1.
Olsen SK, Capili AD, …, Tan DS, Lima CD
Nature 2010 Feb 18 463(7283):906-12 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Walter Chazin

/ Michael Rape

First evaluation 9 Mar 2010 | Latest evaluation 15 Mar 2010

	Must Read
F1000 Factor 6.4

Confirmation

Hypothesis

New Finding

The structure of the peripheral stalk of Thermus thermophilus H+-ATPase/synthase.
Lee LK, Stewart AG, …, Bernal RA, Stock D
Nat Struct Mol Biol 2010 Mar 17(3):373-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Stephan Wilkens

/ Michael Galperin

First evaluation 12 Mar 2010 | Latest evaluation 15 Mar 2010

	Must Read
F1000 Factor 6.4

Hypothesis

New Finding

Regulation of alternative splicing by histone modifications.
Luco RF, Pan Q, …, Pereira-Smith OM, Misteli T
Science 2010 Feb 19 327(5968):996-1000 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Andrea Mattevi / Leonie Ringrose
First evaluation 17 Feb 2010 | Latest evaluation 2 Mar 2010

	Must Read
F1000 Factor 6.4

Hypothesis

New Finding

Novel Drug Target

Kinesin-1/Hsc70-dependent mechanism of slow axonal transport and its relation to fast axonal transport.
Terada S, Kinjo M, …, Takei Y, Hirokawa N
EMBO J 2010 Jan 28 [abstract on PubMed] [related articles] [full text]

Selected by | Linda Amos / Orly Reiner
First evaluation 12 Feb 2010 | Latest evaluation 17 Feb 2010

	Must Read
F1000 Factor 6.4

Hypothesis

New Finding

Tech Advance

Mechanism of folding chamber closure in a group II chaperonin.
Zhang J, Baker ML, …, Frydman J, Chiu W
Nature 2010 Jan 21 463(7279):379-83 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Jose Valpuesta / James Conway
First evaluation 5 Feb 2010 | Latest evaluation 15 Feb 2010

	Must Read
F1000 Factor 4.9

New Finding

PDR-type ABC transporter mediates cellular uptake of the phytohormone abscisic acid.
Kang J, Hwang JU, …, Martinoia E, Lee Y
Proc Natl Acad Sci U S A 2010 Feb 2 107(5):2355-60 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Martin Robert McAinsh / Simon Gilroy / Michael Gjedde Palmgren
First evaluation 15 Feb 2010 | Latest evaluation 8 Mar 2010

	Recommended
F1000 Factor 3.2

Confirmation

Tech Advance

Controversial

A galaxy of folds.
Alva V, Remmert M, …, Lupas AN, Söding J
Protein Sci 2010 Jan 19(1):124-30 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Yuri Wolf / Yuanpeng Janet Huang

First evaluation 17 Feb 2010 | Latest evaluation 10 Mar 2010

	Recommended
F1000 Factor 3.2

Tech Advance

NMR structure determination for larger proteins using backbone-only data.
Raman S, Lange OF, …, Montelione GT, Baker D
Science 2010 Feb 19 327(5968):1014-8 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Gira Bhabha and H Jane Dyson / Antonio Rosato
Evaluated 3 Mar 2010

	Recommended
F1000 Factor 3.2

New Finding

Tech Advance

Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography.
Fernández-Busnadiego R, Zuber B, …, Baumeister W, Lucic V
J Cell Biol 2010 Jan 11 188(1):145-56 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Castle and Lukas Tamm / Martina Serlachius and Pekka Lappalainen
First evaluation 27 Jan 2010 | Latest evaluation 3 Mar 2010

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.