Faculty of 1000 Biology | Current Top 10 > Immunology

28-Nov-2009

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Immunology

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Allergy & Hypersensitivity

Antigen Processing & Recognition

Autoimmunity

Genetics of the Immune System

Immune Response

Immunity to Infections

Immunomodulation

Innate Immunity

Leukocyte Activation

Leukocyte Development

Leukocyte Signalling & Gene Expression

Related Sections

Cellular Microbiology & Pathogenesis

Immunopharmacology & Hematologic Pharmacology

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1

	Exceptional
F1000 Factor 9.9

Hypothesis

New Finding

Controversial

Novel Drug Target

Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome.
Lombardi VC, Ruscetti FW, …, Silverman RH, Mikovits JA
Science 2009 Oct 23 326(5952):585-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Ulf Pettersson / Alan Landay / Brigitte Huber / Adriano Boasso and Gene Shearer
Dissenters | Masahiro Shuda and Patrick S. Moore
First evaluation 13 Nov 2009 | Latest evaluation 18 Nov 2009

2

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria.
Ivanov II, Atarashi K, …, Honda K, Littman DR
Cell 2009 Oct 14 [abstract on PubMed] [related articles] [full text]

Selected by | Dale Umetsu / David Alpers
First evaluation 27 Oct 2009 | Latest evaluation 5 Nov 2009

3

	Must Read
F1000 Factor 6.6

Confirmation

Hypothesis

New Finding

Novel Drug Target

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Ishikawa H, Ma Z, Barber GN
Nature 2009 Oct 8 461(7265):788-92 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Blossom Damania / Alina Peterson and Adolfo Garcia-Sastre / Taro Kawai and Shizuo Akira
First evaluation 23 Oct 2009 | Latest evaluation 9 Nov 2009

4

	Must Read
F1000 Factor 6.5

Hypothesis

New Finding

Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation.
Marks BR, Nowyhed HN, …, Flavell RA, Craft J
Nat Immunol 2009 Oct 10(10):1125-32 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Kranz / Paul Gleeson / Thomas Hunig
First evaluation 5 Oct 2009 | Latest evaluation 9 Nov 2009

5

	Must Read
F1000 Factor 6.4

Hypothesis

New Finding

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Bröske AM, Vockentanz L, …, Jacobsen SE, Rosenbauer F
Nat Genet 2009 Nov 41(11):1207-15 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Claudia Waskow / R Katherine Hyde and Paul Liu

First evaluation 23 Oct 2009 | Latest evaluation 25 Nov 2009

6

	Must Read
F1000 Factor 6.4

Confirmation

Hypothesis

New Finding

CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner.
Chaudhry A, Rudra D, …, Kas A, Rudensky AY
Science 2009 Oct 1 [abstract on PubMed] [related articles] [full text]

Selected by | Scott Lieberman and Laurence Turka / Christian Engwerda
First evaluation 3 Nov 2009 | Latest evaluation 19 Nov 2009

7

	Must Read
F1000 Factor 4.8

Confirmation

New Finding

Novel Drug Target

Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels.
Jha MK, Badou A, …, Flockerzi V, Flavell RA
Nat Immunol 2009 Dec 10(12):1275-82 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | I-Cheng Ho / Steve Ward

First evaluation 5 Nov 2009 | Latest evaluation 24 Nov 2009

8

	Must Read
F1000 Factor 4.8

Hypothesis

New Finding

Mast cell-derived particles deliver peripheral signals to remote lymph nodes.
Kunder CA, St John AL, …, Staats HF, Abraham SN
J Exp Med 2009 Oct 26 206(11):2455-67 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Eric Denkers / Charlotte Weller and Jonathan Lamb
First evaluation 26 Oct 2009 | Latest evaluation 6 Nov 2009

9

	Recommended
F1000 Factor 3.2

Hypothesis

New Finding

Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands.
Barbalat R, Lau L, Locksley RM, Barton GM
Nat Immunol 2009 Nov 10(11):1200-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Clifford Harding / Wolfgang Kastenmuller, Naeha Subramanian and Ronald Germain
First evaluation 28 Oct 2009 | Latest evaluation 4 Nov 2009

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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