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 MOST VIEWED PAPERS | Bioinformatics | calculated on 9 February 2010
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1
Exceptional
F1000 Factor 8.0

New Finding
Tech Advance
 Exome sequencing identifies the cause of a mendelian disorder.
Ng SB, Buckingham KJ, …, Shendure J, Bamshad MJ
Nat Genet 2010 Jan 42(1):30-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard F Wintle and Stephen Scherer / Steven Salzberg
First evaluation 25 Jan 2010 | Latest evaluation 3 Feb 2010

 
2
Recommended
F1000 Factor 3.0

New Finding
 The rate and molecular spectrum of spontaneous mutations in Arabidopsis thaliana.
Ossowski S, Schneeberger K, …, Weigel D, Lynch M
Science 2010 Jan 1 327(5961):92-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yukio Kurihara and Motoaki Seki
Evaluated 27 Jan 2010
 
3
Must Read
F1000 Factor 6.4

Hypothesis
Controversial
 Four stages of a scientific discipline; four types of scientist.
Shneider AM
Trends Biochem Sci 2009 May 34(5):217-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Etienne Joly / Armen Mulkidjanian and Michael Galperin
First evaluation 3 Aug 2009 | Latest evaluation 10 Aug 2009
 
4
Must Read
F1000 Factor 6.4

Confirmation
Hypothesis
New Finding
Controversial
 Horizontal gene transfer of the secretome drives the evolution of bacterial cooperation and virulence.
Nogueira T, Rankin DJ, …, Brown SP, Rocha EP
Curr Biol 2009 Nov 3 19(20):1683-91 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Bas E Dutilh and Martijn Huynen / Jeremy Van Cleve and Steven Frank
First evaluation 22 Jan 2010 | Latest evaluation 29 Jan 2010
 
5
Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
Tech Advance
 Toward a quantitative theory of intrinsically disordered proteins and their function.
Liu J, Faeder JR, Camacho CJ
Proc Natl Acad Sci U S A 2009 Nov 24 106(47):19819-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vladimir Uversky
Evaluated 26 Jan 2010
 
6
Recommended
F1000 Factor 3.0

New Finding
 A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.
Neklesa TK, Davis RW
PLoS Genet 2009 Jun 5(6):e1000515 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tao Xu and Anuj Kumar
Evaluated 28 Jan 2010
 
7
Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Controversial
 Phylogenies reveal new interpretation of speciation and the Red Queen.
Venditti C, Meade A, Pagel M
Nature 2010 Jan 21 463(7279):349-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Timothy Farkas and Patrik Nosil
Evaluated 21 Jan 2010
 
8
Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 De novo assembly of human genomes with massively parallel short read sequencing.
Li R, Zhu H, …, Wang J, Wang J
Genome Res 2009 Dec 17 [abstract on PubMed] [related articles] [full text]
Selected by | Tony Long
Evaluated 26 Jan 2010
 
9
Must Read
F1000 Factor 4.9

Confirmation
Hypothesis
New Finding
 Stepwise modification of a modular enhancer underlies adaptation in a Drosophila population.
Rebeiz M, Pool JE, …, Aquadro CF, Carroll SB
Science 2009 Dec 18 326(5960):1663-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Artyom Kopp / Stuart Macdonald / Luisa Cochella and Oliver Hobert
First evaluation 11 Jan 2010 | Latest evaluation 27 Jan 2010
 
10
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Tech Advance
 Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts.
Jensen MR, Salmon L, Nodet G, Blackledge M
J Am Chem Soc 2010 Jan 11 [abstract on PubMed] [related articles] [full text]
Selected by | Vladimir Uversky
Evaluated 26 Jan 2010

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