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  Sections Covered
Biomacromolecule-Ligand Interactions
Cell Signalling & Trafficking Structures
Experimental Biophysical Methods
Macromolecular Assemblies & Machines
Membrane Proteins & Energy Transduction
Protein Folding
Structural Genomics
Structure: RNA
Structure: Replication & Repair
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Theory & Simulation
Related Sections
Biocatalysis
Protein Chemistry & Proteomics


 MOST VIEWED PAPERS | Structural Biology | calculated on 9 February 2010
 browse faculty | show Most Viewed Papers in

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1
Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
Tech Advance
 Toward a quantitative theory of intrinsically disordered proteins and their function.
Liu J, Faeder JR, Camacho CJ
Proc Natl Acad Sci U S A 2009 Nov 24 106(47):19819-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Vladimir Uversky
Evaluated 26 Jan 2010
 
2
Exceptional
F1000 Factor 9.0

Confirmation
New Finding
Tech Advance
 Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts.
Jensen MR, Salmon L, Nodet G, Blackledge M
J Am Chem Soc 2010 Jan 11 [abstract on PubMed] [related articles] [full text]
Selected by | Vladimir Uversky
Evaluated 26 Jan 2010
 
3
Recommended
F1000 Factor 3.0

Tech Advance
 Infrared laser-mediated gene induction in targeted single cells in vivo.
Kamei Y, Suzuki M, …, Funatsu T, Yuba S
Nat Methods 2009 Jan 6(1):79-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Simon Ebbinghaus and Martin Gruebele
Evaluated 25 Jan 2010
 
4
Recommended
F1000 Factor 3.0

Tech Advance
 The Negatome database: a reference set of non-interacting protein pairs.
Smialowski P, Pagel P, …, Frishman D, Ruepp A
Nucleic Acids Res 2010 Jan 38:D540-4 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Richard Willson
Evaluated 2 Feb 2010
 
5
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
Tech Advance
 A minimal sequence code for switching protein structure and function.
Alexander PA, He Y, …, Orban J, Bryan PN
Proc Natl Acad Sci U S A 2009 Dec 15 106(50):21149-54 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Alina Peterson and Adolfo Garcia-Sastre / Gira Bhabha and H Jane Dyson
First evaluation 6 Jan 2010 | Latest evaluation 12 Jan 2010
 
6
Recommended
F1000 Factor 3.0

New Finding
 Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography.
Fernández-Busnadiego R, Zuber B, …, Baumeister W, Lucic V
J Cell Biol 2010 Jan 11 188(1):145-56 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Castle and Lukas Tamm
Evaluated 27 Jan 2010
 
7
Must Read
F1000 Factor 6.6

Hypothesis
New Finding
Tech Advance
Controversial
 Hidden alternative structures of proline isomerase essential for catalysis.
Fraser JS, Clarkson MW, …, Kern D, Alber T
Nature 2009 Dec 3 462(7273):669-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fred Dyda / Gira Bhabha and H Jane Dyson / David Cowburn
First evaluation 23 Dec 2009 | Latest evaluation 20 Jan 2010
 
8
Exceptional
F1000 Factor 12.8

Hypothesis
New Finding
 Control of gene expression by a natural metabolite-responsive ribozyme.
Winkler WC, Nahvi A, …, Collins JA, Breaker RR
Nature 2004 Mar 18 428(6980):281-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David M.J. Lilley / Richard Maraia / Samuel Butcher / Eric Westhof / Peter Unrau / Scott K Silverman / Fritz Eckstein / Burckhard Seelig / Andrew D Sharrocks / Janet Morrow / Andres Jaschke / John Burke / Reinhard Luehrmann
First evaluation 18 Mar 2004 | Latest evaluation 17 May 2004
 
9
Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Modulation of protein properties in living cells using nanobodies.
Kirchhofer A, Helma J, …, Hopfner KP, Rothbauer U
Nat Struct Mol Biol 2010 Jan 17(1):133-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Sundstrom
Evaluated 15 Jan 2010
 
10
Recommended
F1000 Factor 3.0

Tech Advance
 Hexahistidine-tag-specific optical probes for analyses of proteins and their interactions.
Zhao C, Hellman LM, …, Whiteheart SW, Fried MG
Anal Biochem 2009 Dec 28 [abstract on PubMed] [related articles] [full text]
Selected by | Huaying Zhao and Peter Schuck
Evaluated 5 Feb 2010

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