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Cardiovascular Physiology/Circulation
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Behavioural Neuroscience
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 MOST VIEWED PAPERS | Physiology | calculated on 18 March 2010
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1
Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.
Ziemann AE, Allen JE, …, Welsh MJ, Wemmie JA
Cell 2009 Nov 25 139(5):1012-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Antoine Adamantidis and Luis de Lecea
Evaluated 9 Mar 2010
 
2
Exceptional
F1000 Factor 9.0

New Finding
Novel Drug Target
 Rfx6 directs islet formation and insulin production in mice and humans.
Smith SB, Qu HQ, …, Polychronakos C, German MS
Nature 2010 Feb 11 463(7282):775-80 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Qingchun Tong and Perry Bickel
Evaluated 2 Mar 2010
 
3
Must Read
F1000 Factor 6.0

New Finding
 Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro.
Yagita K, Horie K, …, Takeda J, Uchiyama Y
Proc Natl Acad Sci U S A 2010 Feb 23 107(8):3846-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jennifer A Mohawk and Michael Menaker
Evaluated 1 Mar 2010
 
4
Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
 TRPC1 Is Essential for In Vivo Angiogenesis in Zebrafish.
Yu PC, Gu SY, Bu JW, Du JL
Circ Res 2010 Feb 25 [abstract on PubMed] [related articles] [full text]
Selected by | Bernd Nilius
Evaluated 10 Mar 2010
 
5
Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
 A genome-wide RNAi screen for modifiers of the circadian clock in human cells.
Zhang EE, Liu AC, …, Hogenesch JB, Kay SA
Cell 2009 Oct 2 139(1):199-210 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Pasquale Innominato and Jean Clairambault
Evaluated 19 Feb 2010
 
6
Recommended
F1000 Factor 3.0

Hypothesis
 Structural brain differences and cognitive functioning related to body mass index in older females.
Walther K, Birdsill AC, Glisky EL, Ryan L
Hum Brain Mapp 2009 Dec 8 [abstract on PubMed] [related articles] [full text]
Selected by | Britta Hitze and Achim Peters
Evaluated 2 Mar 2010
 
7
Must Read
F1000 Factor 6.0

New Finding
 FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice.
Rached MT, Kode A, …, Karsenty G, Kousteni S
J Clin Invest 2010 Jan 120(1):357-68 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joshua J Park and Y Peng Loh
Evaluated 11 Mar 2010
 
8
Exceptional
F1000 Factor 9.6

New Finding
Novel Drug Target
 TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.
Kato M, Putta S, …, Rossi JJ, Natarajan R
Nat Cell Biol 2009 Jul 11(7):881-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Chadjichristos Christos and Christos Chatziantoniou / Kent Riemondy and Dominique Eladari
First evaluation 4 Aug 2009 | Latest evaluation 21 Sep 2009
 
9
Exceptional
F1000 Factor 11.1

Hypothesis
New Finding
Tech Advance
 Matrix elasticity directs stem cell lineage specification.
Engler AJ, Sen S, Sweeney HL, Discher DE
Cell 2006 Aug 25 126(4):677-89 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kenneth Yamada / Ray Rodgers / Carol Otey / Paul Bornstein / Avri Ben-Ze'ev / Michel Labouesse / Thomas Egelhoff / Deborah Andrew / Amy Wagers
First evaluation 30 Aug 2006 | Latest evaluation 3 Sep 2007

 
10
Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Novel Drug Target
 Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice.
Sundaresan NR, Gupta M, …, Isbatan A, Gupta MP
J Clin Invest 2009 Sep 119(9):2758-71 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lisa Schwartz Longacre
Evaluated 1 Mar 2010

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